RU 59063
(CID
197655
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
4
)
Unspecified(1)
Top Targets:
NR LBD AR(
1
)
BioAssay Types:
Literature(
5
)
BioActivity Types:
Ki(
2
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 5 Data Row: 5 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
103337296
]
Active
Ki
0.00223
Inhibition of rat prostate cytosolic androgen receptor [AID
238931
, Type: Literature]
View
X
Row No.
1
Structure
Substance
SID
103337296
CID
197655
Outcome
Active
Ki
0.00223 [uM]
BioAssay
Inhibition of rat prostate cytosolic androgen receptor
AID
238931
BioAssay type
Literature
Target
PubMed
15454212
Data Table
2
[SID
103337296
]
Active
Ki
0.00223
Inhibitory constant against rat prostate cytosol androgen receptor using [3H]mibolerone [AID
39296
, Type: Literature]
Androgen receptor [gi:
113832
]
View
X
Row No.
2
Structure
Substance
SID
103337296
CID
197655
Outcome
Active
Ki
0.00223 [uM]
BioAssay
Inhibitory constant against rat prostate cytosol androgen receptor using [3H]mibolerone
AID
39296
BioAssay type
Literature
Target
Androgen receptor [gi:
113832
]
PubMed
10966753
Data Table
3
[SID
103337296
]
Active
Ki
0.00223
Inhibitory constant against rat prostate cytosol androgen receptor using [3H]mibolerone [AID
39296
, Type: Literature]
Androgen receptor [gi:
113832
]
View
X
Row No.
3
Structure
Substance
SID
103337296
CID
197655
Outcome
Active
Ki
0.00223 [uM]
BioAssay
Inhibitory constant against rat prostate cytosol androgen receptor using [3H]mibolerone
AID
39296
BioAssay type
Literature
Target
Androgen receptor [gi:
113832
]
PubMed
10966753
Data Table
4
[SID
103337296
]
Active
Inhibition of prostate specific antigen expression in human LNCAP cells at 1.25 to 10 uM in presence of fetal bovine serum [AID
482787
, Type: Literature]
View
X
Row No.
4
Structure
Substance
SID
103337296
CID
197655
Outcome
Active
BioAssay
Inhibition of prostate specific antigen expression in human LNCAP cells at 1.25 to 10 uM in presence of fetal bovine serum
AID
482787
BioAssay type
Literature
Target
PubMed
20218717
Data Table
5
[SID
103337296
]
Active
Inhibition of prostate specific antigen expression in human LNCAP cells at 0.625 to 20 uM in presence of fetal bovine serum [AID
482784
, Type: Literature]
View
X
Row No.
5
Structure
Substance
SID
103337296
CID
197655
Outcome
Active
BioAssay
Inhibition of prostate specific antigen expression in human LNCAP cells at 0.625 to 20 uM in presence of fetal bovine serum
AID
482784
BioAssay type
Literature
Target
PubMed
20218717
Data Table
6
[SID
103337296
]
Unspecified
Inhibition of [3H]mibolerone binding to cytosolic androgen receptor of rat ventral prostrate [AID
239949
, Type: Literature]
View
X
Row No.
6
Structure
Substance
SID
103337296
CID
197655
Outcome
Unspecified
BioAssay
Inhibition of [3H]mibolerone binding to cytosolic androgen receptor of rat ventral prostrate
AID
239949
BioAssay type
Literature
Target
PubMed
15715462
Data Table