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BioActivity Data for Compound denatonium benzoate (CID 19518)

BioActivity Outcomes:
Active(4)
 
 
Inactive(798)
 
 
Inconclusive(29)
 
 
Unspecified(5)
 
 
Top Targets:
7tm 4(28)
 
 
NR LBD PPAR(21)
 
 
 
NR LBD AR(16)
 
 
NR LBD ER(16)
 
 
NR LBD VDR(13)
 
 
BioAssay Types:
Confirmatory(366)
 
 
 
 
 
Screening(313)
 
 
Literature(74)
 
 
 
 
Summary(48)
 
 
 
BioAssay Categories:
In vivo(2)
 
 
Biochemical(106)
 
 
Toxicity(27)
 
 
 
 
 
Cell-based(101)
 
 
Organism-base..(8)
 
 
BioActivity Types:
Potency(362)
 
 
 
 
 
IC50(11)
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 597    Data Row: 836   Total Pages: 42   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID11112959]
Potency 0.0079qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6 [AID891, Type: confirmatory]cytochrome P450 2D6 isoform 1 [Homo sapiens] [gi:40805836]
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2
[SID144211904]
Potency-Replicate_1 30.6379qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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3
[SID144211904]
Potency-Replicate_1 43.2771qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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4
[SID11112959]
Cytochrome panel assay with activity outcomes [AID1851_2, Type: other]cytochrome P450 2D6 isoform 2 [Homo sapiens] [gi:68509921]
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5
[SID26757851]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
View
6
[SID104171335]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
View
7
[SID11112959]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
View
8
[SID26757851]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
9
[SID56463089]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
10
[SID170464678]
Ac50 0.630957qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
View
11
[SID170464678]
Ac50 0.630957qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, blue channel [AID1117314, Type: confirmatory]
View
12
[SID11112959]
Potency 1.4125qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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13
[SID170464678]
Ac50 3.16228qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green channel [AID1117310, Type: confirmatory]
View
14
[SID144211904]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743215, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
15
[SID144211904]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743212, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
16
[SID170464678]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743215, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
17
[SID170464678]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743212, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
18
[SID170464678]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743226, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
19
[SID170464678]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
20
[SID144211904]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743226, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View