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AC1LZ0JG (CID 1911770) - Compound BioActivity Data
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BioActivity Outcomes:
Active(52)
 
 
Inactive(547)
 
 
Inconclusive(46)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(37)
 
 
 
G-alpha(8)
 
 
 
DUF3371(7)
 
 
 
Tryp SPc(7)
 
 
 
Esterase lipa..(7)
 
 
 
BioAssay Types:
Screening(431)
 
 
 
 
Confirmatory(196)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(132)
 
 
 
 
 
IC50(39)
 
 
 
 
AC50(10)
 
 
 
EC50(7)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 586    Data Row: 646   Total Pages: 33   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26726094]
Potency 1.8888qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
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2
[SID26726094]
Potency 2.9093qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID26726094]
AC50_uM 2.978Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Cancer Stem Cells [AID449748, Type: confirmatory]
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4
[SID26726094]
Potency 3.6626qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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5
[SID26726094]
AC50_uM 4.541Dose Response HTS Screen to Identify Cytotoxic Compounds of HMLE_sh_eGFP [AID463074, Type: confirmatory]
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6
[SID26726094]
Potency 5.6234VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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7
[SID26726094]
Potency 7.3078A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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8
[SID26726094]
Potency 7.9433qHTS for Inhibitors of Cell Surface uPA Generation [AID540303, Type: confirmatory]urokinase plasminogen activator surface receptor precursor [Mus musculus] [gi:7242179]
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9
[SID26726094]
Potency 7.9433qHTS for Inhibitors of Cell Surface uPA Generation [AID540303, Type: confirmatory]urokinase-type plasminogen activator precursor [Mus musculus] [gi:6679377]
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10
[SID26726094]
Potency 7.9433qHTS for Inhibitors of Cell Surface uPA Generation [AID540303, Type: confirmatory]plasminogen precursor [Mus musculus] [gi:257471003]
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11
[SID26726094]
Potency 11.2202qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins [AID485364, Type: confirmatory]thioredoxin glutathione reductase [Schistosoma mansoni] [gi:15149312]
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12
[SID26726094]
Potency 12.5893qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1468, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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13
[SID26726094]
Potency 17.7828qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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14
[SID26726094]
IC50_Mean 27.739Concentration-Response Confirmation Assays for HCS to Identify Inhibitors of Dynein Mediated Cargo Transport on Microtubules [AID463136, Type: confirmatory]
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15
[SID26726094]
Potency 35.4813qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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16
[SID26726094]
Potency 50.1187qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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17
[SID26726094]
Second counter screen for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4): Non-induced cells with the primary screen assay without carbachol activation [AID493001, Type: screening]regulator of G-protein signaling 4 isoform 2 [Homo sapiens] [gi:5032039]
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18
[SID26726094]
Confirmation assay for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID1053136, Type: screening]integrase, partial [Human immunodeficiency virus 1] [gi:2853980]
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19
[SID26726094]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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20
[SID26726094]
Confirmation assay for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID1053136, Type: screening]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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