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Adenine (CID 190) - Compound BioActivity Data
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BioActivity Outcomes:
Active(28)
 
 
Inactive(808)
 
 
Inconclusive(38)
 
 
Unspecified(76)
 
 
Top Targets:
7tm 4(28)
 
 
 
NR LBD PPAR(16)
 
 
 
NR LBD AR(14)
 
 
 
NR LBD ER(14)
 
 
 
NR LBD VDR(10)
 
 
 
BioAssay Types:
Confirmatory(354)
 
 
 
 
 
Screening(341)
 
 
 
Literature(171)
 
 
 
 
Summary(48)
 
 
 
 
BioActivity Types:
Potency(313)
 
 
 
 
 
IC50(20)
 
 
 
 
Kd(10)
 
 
Ki(6)
 
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 725    Data Row: 950   Total Pages: 48   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46393497]
Kd 0.001Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]
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2
[SID46393497]
Kd 0.001Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]
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3
[SID87557206]
Kd 0.00633Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of Active Ribosome Inactivating Protein From Maize (B-32), Complex With Adenine [gi:167744906]
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4
[SID87557206]
Kd 0.00633Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of Active Ribosome Inactivating Protein From Maize (B-32), Complex With Adenine [gi:167744906]
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5
[SID103517679]
Ki 0.0292Displacement of [3H]adenine from adenine 1 receptor in rat brain cortical membrane by liquid scintillation counting [AID445467, Type: Literature]
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6
[SID103517679]
Ki 0.0471Displacement of [3H]adenine from adenine 1 receptor in HEK293 cells by liquid scintillation counting [AID445471, Type: Literature]
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7
[SID103517679]
Ki 0.28Displacement of [2,8-3H]-adenosine from Trypanosoma brucei AT1/P2 expressed in bloodstream stage of Trypanosoma brucei brucei B48 [AID1065710, Type: Literature]
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8
[SID103517679]
IC50 8.29Agonist activity at rat adenine 1 receptor expressed in human 1321N1 cells assessed as inhibition of isoproterenol-induced [3H]cAMP formation by scintillation counting [AID445475, Type: Literature]
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9
[SID103517679]
IC50 10.89Inhibition of human xanthine oxidase [AID287937, Type: Literature]Xanthine dehydrogenase/oxidase [gi:2506326]
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10
[SID103517679]
IC50 12Potency against non nucleoside reverse transcriptor was determined in MT-4 cells [AID105205, Type: Literature]
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11
[SID47193680]
Potency 14.1254qHTS of TDP-43 Inhibitors [AID652104, Type: confirmatory]TAR DNA-binding protein 43 [gi:20140568]
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12
[SID170465950]
Ratio Potency (uM) 33.4889qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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13
[SID170483059]
Kd 180Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of Hpnmt In Complex Adohcy And Adenine [gi:307776418]
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14
[SID170483059]
Kd 180Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of Hpnmt In Complex Adohcy And Adenine [gi:307776418]
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15
[SID46392627]
Kd 260Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Complex Of [e160a-E189a] Trichosanthin And Adenine [gi:28374046]
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16
[SID46392627]
Kd 260Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Complex Of [e160a-E189a] Trichosanthin And Adenine [gi:28374046]
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17
[SID46392320]
Ki 300Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of E. Coli MtaADOHCY NUCLEOSIDASE [gi:24158768]
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18
[SID46392320]
Ki 300Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of E. Coli MtaADOHCY NUCLEOSIDASE [gi:24158768]
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19
[SID53812922]
Kd 700Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Ricin A-Chain (Recombinant) Complex With Adenine [gi:160877710]
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20
[SID53812922]
Kd 700Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Ricin A-Chain (Recombinant) Complex With Adenine [gi:160877710]
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