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Mannose (CID 18950) - Compound BioActivity Data
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BioActivity Outcomes:
Inactive(494)
 
 
Inconclusive(1)
 
 
Unspecified(26)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
7TM GPCR Srsx(15)
 
 
CAP ED(5)
 
 
CLECT DC-SIGN..(5)
 
 
TRP 2(5)
 
 
BioAssay Types:
Screening(353)
 
 
Confirmatory(134)
 
 
 
 
Literature(30)
 
 
 
BioActivity Types:
Potency(122)
 
 
 
 
IC50(15)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 475    Data Row: 521   Total Pages: 11   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103583168]
IC50 5300Inhibitory concentration against mannan binding relative to concanavalin A; Using QCM(quartz crystal microbalance) assay [AID241553, Type: Literature]
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2
[SID103583168]
IC50 10456Displacement of yeast mannan from Concanavalin A by Enzyme-linked lectin assay [AID596531, Type: Literature]
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3
[SID103583168]
IC50 20000Inhibitory activity against Mannosidase in jack bean (Canavalia ensiformis) [AID108106, Type: Literature]
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4
[SID103583168]
MIC 50000Anticryptosporidial activity against Cryptosporidium parvum GCH1 assessed as inhibition of rabbit erythrocytes hemagglutination [AID381592, Type: Literature]
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5
[SID103583168]
MIC 100000Anticryptosporidial activity against Cryptosporidium hominis TU502 assessed as inhibition of rabbit erythrocytes hemagglutination [AID381594, Type: Literature]
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6
[SID103583168]
IC50 500000Inhibition of Cryptosporidium parvum recombinant Galactose/N-acetylgalactosamine-specific lectin binding to Caco2A cells [AID381596, Type: Literature]
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7
[SID103583168]
Inhibition of Cryptosporidium parvum recombinant Galactose/N-acetylgalactosamine-specific lectin binding to Caco2A cells relative to galactose [AID381597, Type: Literature]
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8
[SID103583168]
Inhibition of Drosophila melanogaster GM2b at 5 mM by spectrophotometry [AID587707, Type: Literature]Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B [gi:45645028]
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9
[SID103583168]
Inhibition of Drosophila melanogaster LM408 at 5 mM by spectrophotometry [AID587709, Type: Literature]
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10
[SID103583168]
Ratio of methyl alpha-D-mannoside IC50 to compound IC50 for binding affinity to Concanavalin A [AID596530, Type: Literature]
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11
[SID103583168]
Ratio of Kcat to Km for Neisseria meningitidis lgtC [AID500279, Type: Literature]
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12
[SID103583168]
Ratio of methyl alpha-D-mannoside IC50 to compound IC50 for binding affinity to Concanavalin A per carbohydrate moiety [AID596532, Type: Literature]
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13
[SID103583168]
Displacement of biotinylated-TM PAA from Escherichia coli FimH expressed in Escherichia coli HM125 at 50 mM after 3 hrs by colorimetry [AID709926, Type: Literature]
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14
[SID103583168]
Anticryptosporidial activity against Cryptosporidium hominis TU502 assessed as inhibition of rabbit erythrocytes hemagglutination relative to galactose [AID381595, Type: Literature]
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15
[SID103583168]
Compound was tested for inhibition of Human acrosin by aldohexoses [AID30427, Type: Literature]
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16
[SID103583168]
Compound was tested for inhibition of Human acrosin by aldoses [AID30429, Type: Literature]
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17
[SID103583168]
Anticryptosporidial activity against Cryptosporidium parvum GCH1 assessed as inhibition of rabbit erythrocytes hemagglutination relative to galactose [AID381593, Type: Literature]
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18
[SID56323500]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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19
[SID103583168]
Displacement of biotinylated-TM PAA from human Dectin-2 at 50 mM after 3 hrs by colorimetry [AID709909, Type: Literature]C-type lectin domain family 6 member A [gi:59797926]
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20
[SID103583168]
Displacement of biotinylated-TM PAA from human DLEC at 50 mM after 3 hrs by colorimetry [AID709908, Type: Literature]C-type lectin domain family 4 member C [gi:59797957]
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21
[SID103583168]
Displacement of biotinylated-TM PAA from human DC-SIGNR at 50 mM after 3 hrs by colorimetry [AID709913, Type: Literature]C-type lectin domain family 4 member M [gi:46395990]
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22
[SID103583168]
Displacement of biotinylated-TM PAA from human DC-SIGN at 50 mM after 3 hrs by colorimetry [AID709914, Type: Literature]CD209 antigen [gi:46396012]
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23
[SID103583168]
Displacement of biotinylated-TM PAA from human langerin at 50 mM after 3 hrs by colorimetry [AID709910, Type: Literature]C-type lectin domain family 4 member K [gi:229784129]
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24
[SID103583168]
Displacement of biotinylated-TM PAA from human MBP at 50 mM after 3 hrs by colorimetry [AID709915, Type: Literature]Mannose-binding protein C [gi:126676]
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25
[SID103583168]
Displacement of biotinylated-TM PAA from human MMR at 50 mM after 3 hrs by colorimetry [AID709912, Type: Literature]Macrophage mannose receptor 1 [gi:126730]
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26
[SID103583168]
Displacement of biotinylated-TM PAA from human SP-D at 50 mM after 3 hrs by colorimetry [AID709911, Type: Literature]Pulmonary surfactant-associated protein D [gi:317373510]
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27
[SID29217866]
Potency 13.3714qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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28
[SID56323500]
Potency 18.526Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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29
[SID56323500]
Potency 100HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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30
[SID56323500]
Identification of agents that induce E-selectin on human endothelial cells Measured in Cell-Based System Using Imaging - 2152-01_Activator_SinglePoint_HTS_Activity [AID686992, Type: screening]E-selectin precursor [Homo sapiens] [gi:187960042]
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31
[SID56323500]
Potency qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter [AID463254, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
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32
[SID29217866]
Potency VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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33
[SID29217866]
Potency qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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34
[SID29217866]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
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35
[SID29217866]
Potency Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
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36
[SID56323500]
Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of TLR9-MyD88 binding. [AID504734, Type: screening]toll-like receptor 9 [Homo sapiens] [gi:194068499]
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37
[SID56323500]
Primary cell-based high-throughput screening for identification of compounds that activate MrgX1 receptor signaling [AID588627, Type: screening]MAS-related GPR member X1 [Homo sapiens] [gi:195969650]
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38
[SID56323500]
Primary cell-based high-throughput screening for identification of compounds that allosterically activate MrgX1 receptor signaling [AID588675, Type: screening]MAS-related GPR member X1 [Homo sapiens] [gi:195969650]
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39
[SID56323500]
Primary cell-based high-throughput screening for identification of compounds that antagonize MrgX1 receptor signaling [AID588676, Type: screening]MAS-related GPR member X1 [Homo sapiens] [gi:195969650]
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40
[SID56323500]
TR-FRET-based primary biochemical high throughput screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3). [AID2300, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
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41
[SID56323500]
Luminescence-based cell-based high throughput primary screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID602229, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
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42
[SID56323500]
Identification of inhibitors of RAD54 Measured in Biochemical System Using Plate Reader - 2159-01_Inhibitor_SinglePoint_HTS_Activity [AID602329, Type: screening]DNA repair and recombination protein RAD54-like [Homo sapiens] [gi:216548193]
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43
[SID56323500]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4) (1536 HTS) [AID485272, Type: screening]protein-arginine deiminase type-4 [Homo sapiens] [gi:216548487]
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44
[SID56323500]
Fluorescent Biochemical Primary HTS to Identify Inhibitors of P. aeruginosa PvdQ acylase Measured in Biochemical System Using Plate Reader and Imaging Combination - 2091-01_Inhibitor_SinglePoint_HTS_Activity [AID488965, Type: screening]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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45
[SID56323500]
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB) [AID504411, Type: screening]sn1-specific diacylglycerol lipase beta isoform 1 [Homo sapiens] [gi:218931251]
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46
[SID56323500]
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast [AID2825, Type: screening]NLRP3 protein [Homo sapiens] [gi:219518789]
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47
[SID56323500]
IC50 Primary and Confirmatory Screening for Flavivirus Genomic Capping Enzyme Inhibition [AID588689, Type: confirmatory]Chain A, Crystal Structure Of Dengue-2 Virus Methyltransferase Complexed With S-Adenosyl-L-Homocysteine [gi:219689243]
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48
[SID56323500]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the orexin 1 receptor (OX1R; HCRTR1) [AID434989, Type: screening]orexin receptor type 1 [Homo sapiens] [gi:222080095]
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49
[SID56323500]
FRET-based cell-based primary high throughput screening assay to identify antagonists of the orexin 1 receptor (OX1R; HCRTR1) [AID485270, Type: screening]orexin receptor type 1 [Homo sapiens] [gi:222080095]
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50
[SID56323500]
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1). [AID720700, Type: screening]Phospholipase C, gamma 1 [Homo sapiens] [gi:223459640]
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