CHEMBL427379
(CID
18614749
) -
BioAssay Data Summary for Compound
.
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BioActivity Outcomes:
Active(3)
Top Targets:
Neur chan LBD(
2
)
BioAssay Types:
Literature(
3
)
BioActivity Types:
IC50(
3
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 3 Data Row: 3 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
103483504
]
Active
IC50
0.004
Selectivity for housefly GABA receptor over mouse GABA receptor [AID
261982
, Type: Literature]
View
X
Row No.
1
Structure
Substance
SID
103483504
CID
18614749
Outcome
Active
IC50
0.004 [uM]
BioAssay
Selectivity for housefly GABA receptor over mouse GABA receptor
AID
261982
BioAssay type
Literature
Target
PubMed
16386419
Data Table
2
[SID
103483504
]
Active
IC50
0.074
Displacement of [3H]EBOB from housefly neuronal membrane GABA receptor [AID
261980
, Type: Literature]
Gamma-aminobutyric acid receptor subunit beta [gi:
74919269
]
View
X
Row No.
2
Structure
Substance
SID
103483504
CID
18614749
Outcome
Active
IC50
0.074 [uM]
BioAssay
Displacement of [3H]EBOB from housefly neuronal membrane GABA receptor
AID
261980
BioAssay type
Literature
Target
Gamma-aminobutyric acid receptor subunit beta [gi:
74919269
]
PubMed
16386419
Data Table
3
[SID
103483504
]
Active
IC50
0.3
Binding affinity to mouse brain GABA receptor [AID
261981
, Type: Literature]
Gamma-aminobutyric acid receptor subunit alpha-6 [gi:
341941084
]
View
X
Row No.
3
Structure
Substance
SID
103483504
CID
18614749
Outcome
Active
IC50
0.3 [uM]
BioAssay
Binding affinity to mouse brain GABA receptor
AID
261981
BioAssay type
Literature
Target
Gamma-aminobutyric acid receptor subunit alpha-6 [gi:
341941084
]
PubMed
16386419
Data Table