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SureCN7165042 (CID 18546352) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Unspecified(5)
 
 
Top Targets:
prostaglandin..(3)
 
 
Chemokine CXC(1)
 
 
BioAssay Types:
Literature(6)
 
 
 
BioActivity Types:
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 6   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103568331]
IC50 0.009Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]Interleukin-8 [gi:124359]
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2
[SID103568331]
Inhibition of ovine COX1 at 4 uM for 17 mins pre-incubated before addition of [1-14C]arachidonic acid [AID325051, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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3
[SID103568331]
Inhibition of mouse COX2 at 4 uM for 17 mins pre-incubated before addition of [1-14C]arachidonic acid [AID325052, Type: Literature]Prostaglandin G/H synthase 2 [gi:548483]
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4
[SID103568331]
Inhibition of human COX2 at 4 uM for 17 mins pre-incubated before addition of [1-14C]arachidonic acid [AID325053, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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5
[SID103568331]
Cytotoxicity against of human polymorphonuclear leukocytes assessed as cell viability by trypan blue dye exclusion assay [AID426393, Type: Literature]
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6
[SID103568331]
Cytotoxicity against mouse L1.2 cells assessed as cell viability by trypan blue dye exclusion assay [AID426478, Type: Literature]
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