SureCN7166134
(CID
18546323
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Unspecified(3)
Top Targets:
Chemokine CXC(
1
)
BioAssay Types:
Literature(
3
)
BioActivity Types:
IC50(
1
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 3 Data Row: 3 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
103688113
]
Unspecified
IC50
1
Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID
426392
, Type: Literature]
Interleukin-8 [gi:
124359
]
View
X
Row No.
1
Structure
Substance
SID
103688113
CID
18546323
Outcome
Unspecified
IC50
1 [uM]
BioAssay
Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay
AID
426392
BioAssay type
Literature
Target
Interleukin-8 [gi:
124359
]
PubMed
19560921
Data Table
2
[SID
103688113
]
Unspecified
IC50
1
Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID
426392
, Type: Literature]
Interleukin-8 [gi:
124359
]
View
X
Row No.
2
Structure
Substance
SID
103688113
CID
18546323
Outcome
Unspecified
IC50
1 [uM]
BioAssay
Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay
AID
426392
BioAssay type
Literature
Target
Interleukin-8 [gi:
124359
]
PubMed
19560921
Data Table
3
[SID
103688113
]
Unspecified
IC50
1
Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID
426392
, Type: Literature]
Interleukin-8 [gi:
124359
]
View
X
Row No.
3
Structure
Substance
SID
103688113
CID
18546323
Outcome
Unspecified
IC50
1 [uM]
BioAssay
Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay
AID
426392
BioAssay type
Literature
Target
Interleukin-8 [gi:
124359
]
PubMed
19560921
Data Table
4
[SID
103688113
]
Unspecified
Cytotoxicity against mouse L1.2 cells assessed as cell viability by trypan blue dye exclusion assay [AID
426478
, Type: Literature]
View
X
Row No.
4
Structure
Substance
SID
103688113
CID
18546323
Outcome
Unspecified
BioAssay
Cytotoxicity against mouse L1.2 cells assessed as cell viability by trypan blue dye exclusion assay
AID
426478
BioAssay type
Literature
Target
PubMed
19560921
Data Table
5
[SID
103688113
]
Unspecified
Cytotoxicity against of human polymorphonuclear leukocytes assessed as cell viability by trypan blue dye exclusion assay [AID
426393
, Type: Literature]
View
X
Row No.
5
Structure
Substance
SID
103688113
CID
18546323
Outcome
Unspecified
BioAssay
Cytotoxicity against of human polymorphonuclear leukocytes assessed as cell viability by trypan blue dye exclusion assay
AID
426393
BioAssay type
Literature
Target
PubMed
19560921
Data Table