Acetone (CID 180) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Inactive(232)
 
 
Inconclusive(10)
 
 
Unspecified(26)
 
 
Top Targets:
NR LBD PPAR(5)
 
 
NR LBD TR(4)
 
 
P53(3)
 
 
NR LBD VDR(3)
 
 
NR LBD ROR li..(3)
 
 
BioAssay Types:
Confirmatory(168)
 
 
 
Literature(88)
 
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(132)
 
 
 
IC50(1)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 201    Data Row: 270   Total Pages: 6   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103176148]
Ki 30Compound was tested for binding affinity against hydroxynitrile lyase [AID93047, Type: Literature]
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2
[SID48414925]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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3
[SID17389680]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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4
[SID103176148]
Toxicity determined using Golden Orfe Fish Test [AID101345, Type: Literature]
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5
[SID103176148]
Toxicity determined using Microtox Test [AID159270, Type: Literature]
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6
[SID103176148]
The toxicity of compound was determined using Konemann's Industrial Pollutants Toxicity Test [AID162230, Type: Literature]
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7
[SID103176148]
Eye irritation potential accessed using Draize in vivo rabbit eye irritation test [AID167125, Type: Literature]
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8
[SID103176148]
Inhibition of Rana pipiens muscle activity. [AID168703, Type: Literature]
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9
[SID103176148]
Toxicity determined using Tadpole Narcosis Test [AID212400, Type: Literature]
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10
[SID103176148]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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11
[SID103176148]
IC50 Inhibitory concentration of compound on nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages [AID248765, Type: Literature]
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12
[SID103176148]
Octanol-water partition coefficient, log P of the compound [AID343683, Type: Literature]
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13
[SID103176148]
Alkane-water partition coefficient, log P of the compound [AID343684, Type: Literature]
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14
[SID103176148]
Binding affinity to beta cyclodextrin [AID346025, Type: Literature]
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15
[SID103176148]
Partition coefficient (logP) (benzene) [AID23252, Type: Literature]
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16
[SID103176148]
Partition coefficient (logP) (carbon tetrachloride) [AID23253, Type: Literature]
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17
[SID103176148]
Partition coefficient (logP) (chloroform) [AID23254, Type: Literature]
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18
[SID103176148]
Partition coefficient (logP) [AID23251, Type: Literature]
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19
[SID103176148]
Partition coefficient (logP) (ether) [AID23255, Type: Literature]
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20
[SID103176148]
Partition coefficient (logP) (hexane) [AID23256, Type: Literature]
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21
[SID103176148]
Partition coefficient (logP) [AID23443, Type: Literature]
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22
[SID103176148]
logBB, log(C brain / C blood) [AID26047, Type: Literature]
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23
[SID17389680]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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24
[SID103176148]
Antifungal activity against Microbotryum violaceum assessed as zone of inhibition measured as radius at 50 ug by agar diffusion assay [AID592501, Type: Literature]
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25
[SID103176148]
Antibacterial activity against Legionella pneumophila Corby by microtiter plate assay [AID592502, Type: Literature]
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26
[SID103176148]
In-vitro air to lung partition coefficients of the compound, logK(lung) (human/rat) [AID603950, Type: Literature]
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27
[SID103176148]
In-vitro air to blood partition coefficients of the compound, logK(blood) (human/rat) [AID603951, Type: Literature]
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28
[SID103176148]
In-vitro blood to lung partition coefficients of the compound, logP(lung) (human/rat) [AID603952, Type: Literature]
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29
[SID17389680]
Potency qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 1 hr assay [AID651754, Type: confirmatory]
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30
[SID17389680]
Potency qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 5 hr assay [AID651755, Type: confirmatory]
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31
[SID17389680]
Potency qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
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32
[SID17389680]
Potency qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
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33
[SID17389680]
Potency qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
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34
[SID17389680]
Potency qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
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35
[SID17389680]
Potency qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
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36
[SID17389680]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_44, Type: Literature]
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37
[SID17389680]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_45, Type: Literature]
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38
[SID17389680]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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39
[SID17389680]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
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40
[SID17389680]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
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41
[SID17389680]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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42
[SID17389680]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_5, Type: other]
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43
[SID17389680]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
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44
[SID17389680]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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45
[SID17389680]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_8, Type: other]
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46
[SID144204647]
qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]
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47
[SID17389680]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_30, Type: Literature]
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48
[SID17389680]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_31, Type: Literature]
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49
[SID17389680]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_32, Type: Literature]
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50
[SID17389680]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_33, Type: Literature]
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