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Acetone (CID 180) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(379)
 
 
Inconclusive(21)
 
 
Unspecified(26)
 
 
Top Targets:
NR LBD ER(16)
 
 
NR LBD AR(16)
 
 
NR LBD PPAR(15)
 
 
 
NR LBD TR(10)
 
 
 
NR LBD GR(10)
 
 
 
BioAssay Types:
Confirmatory(287)
 
 
 
Literature(88)
 
 
 
 
 
Summary(39)
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(281)
 
 
 
Ki(1)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 295    Data Row: 428   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103176148]
Ki 30Compound was tested for binding affinity against hydroxynitrile lyase [AID93047, Type: Literature]
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2
[SID48414925]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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3
[SID103176148]
LC50 1.81552e+08Toxicity determined using Golden Orfe Fish Test [AID101345, Type: Literature]
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4
[SID103176148]
LC50 1.09648e+11The toxicity of compound was determined using Konemann's Industrial Pollutants Toxicity Test [AID162230, Type: Literature]
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5
[SID103176148]
Eye irritation potential accessed using Draize in vivo rabbit eye irritation test [AID167125, Type: Literature]
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6
[SID103176148]
Inhibition of Rana pipiens muscle activity. [AID168703, Type: Literature]
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7
[SID103176148]
Toxicity determined using Tadpole Narcosis Test [AID212400, Type: Literature]
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8
[SID103176148]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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9
[SID103176148]
IC50 Inhibitory concentration of compound on nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages [AID248765, Type: Literature]
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10
[SID103176148]
Octanol-water partition coefficient, log P of the compound [AID343683, Type: Literature]
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11
[SID103176148]
Alkane-water partition coefficient, log P of the compound [AID343684, Type: Literature]
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12
[SID103176148]
Binding affinity to beta cyclodextrin [AID346025, Type: Literature]
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13
[SID103176148]
Antifungal activity against Microbotryum violaceum assessed as zone of inhibition measured as radius at 50 ug by agar diffusion assay [AID592501, Type: Literature]
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14
[SID103176148]
Antibacterial activity against Legionella pneumophila Corby by microtiter plate assay [AID592502, Type: Literature]
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15
[SID103176148]
In-vitro air to lung partition coefficients of the compound, logK(lung) (human/rat) [AID603950, Type: Literature]
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16
[SID103176148]
In-vitro air to blood partition coefficients of the compound, logK(blood) (human/rat) [AID603951, Type: Literature]
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17
[SID103176148]
In-vitro blood to lung partition coefficients of the compound, logP(lung) (human/rat) [AID603952, Type: Literature]
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18
[SID17389680]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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19
[SID103176148]
Toxicity determined using Microtox Test [AID159270, Type: Literature]
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20
[SID103176148]
Partition coefficient (logP) [AID23251, Type: Literature]
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21
[SID103176148]
Partition coefficient (logP) (benzene) [AID23252, Type: Literature]
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22
[SID103176148]
Partition coefficient (logP) (carbon tetrachloride) [AID23253, Type: Literature]
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23
[SID103176148]
Partition coefficient (logP) (chloroform) [AID23254, Type: Literature]
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24
[SID103176148]
Partition coefficient (logP) (ether) [AID23255, Type: Literature]
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25
[SID103176148]
Partition coefficient (logP) (hexane) [AID23256, Type: Literature]
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26
[SID103176148]
Partition coefficient (logP) [AID23443, Type: Literature]
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27
[SID103176148]
logBB, log(C brain / C blood) [AID26047, Type: Literature]
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28
[SID17389680]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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29
[SID144209678]
Potency-Replicate_1 6.2704qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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30
[SID144209678]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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31
[SID144209678]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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32
[SID144204647]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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33
[SID144204647]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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34
[SID144209678]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743212, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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35
[SID144209678]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743226, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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36
[SID144209678]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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37
[SID144209678]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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38
[SID144204647]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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39
[SID144204647]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
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40
[SID144204647]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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41
[SID144204647]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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42
[SID144209678]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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43
[SID144209678]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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44
[SID17389680]
Potency Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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45
[SID144204647]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway [AID720692, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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46
[SID17389680]
Potency qHTS assay for small molecule agonists of glucocorticoid receptor signaling [AID588532, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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47
[SID17389680]
Potency qHTS assay for small molecule antagonists of glucocorticoid receptor signaling [AID588533, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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48
[SID17389680]
Potency qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2) [AID881, Type: confirmatory]Arachidonate 15-lipoxygenase B [gi:317373425]
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49
[SID17389680]
Potency qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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50
[SID17389680]
Potency qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling [AID588546, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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