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MLS000067505 (CID 1796110) - Compound BioActivity Data
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BioActivity Outcomes:
Active(142)
 
 
Inactive(598)
 
 
Inconclusive(52)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(42)
 
 
 
Bcl-2 like(13)
 
 
 
alkPPc(10)
 
 
Esterase lipa..(9)
 
 
 
Tryp SPc(8)
 
 
BioAssay Types:
Screening(514)
 
 
 
 
Confirmatory(248)
 
 
 
 
 
Literature(11)
 
 
 
BioActivity Types:
Potency(158)
 
 
 
 
 
IC50(52)
 
 
 
 
EC50(23)
 
 
 
AC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 721    Data Row: 793   Total Pages: 40   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14723512]
Absolute IC50 0.42Dose Response Confirmation for Small Molecule Inhibitors of Epstein-Barr Virus [AID1419, Type: confirmatory]BZLF2 [Human herpesvirus 4 type 2] [gi:139424501]
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2
[SID14723512]
EC50_uM 0.9401Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction [AID435023, Type: confirmatory]LANA [Human herpesvirus 8] [gi:139472804]
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3
[SID14723512]
AC50_uM 1.04Inhibitors of Mycobacterium tuberculosis UDP-galactopyranose mutase (UGM) enzyme Measured in Biochemical System Using Plate Reader - 2105-02_Inhibitor_Dose_CherryPick_Activity [AID540359, Type: confirmatory]UDP-galactopyranose mutase [Mycobacterium tuberculosis H37Rv] [gi:15610945]
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4
[SID14723512]
AC50_uM 1.13Fluorescence polarization to screen for inhibitors that disrupt the protein-protein interaction between Keap1 and Nrf2 Measured in Biochemical System Using Plate Reader - 2119-01_Inhibitor_Dose_CherryPick_Activity [AID588683, Type: confirmatory]kelch-like ECH-associated protein 1 [Homo sapiens] [gi:45269145]
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5
[SID14723512]
AC50_uM 1.13Fluorescence polarization to screen for inhibitors that disrupt the protein-protein interaction between Keap1 and Nrf2 Measured in Biochemical System Using Plate Reader - 2119-01_Inhibitor_Dose_CherryPick_Activity [AID588683, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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6
[SID14723512]
AC50_uM 2.255C-LANA Counter Screen: DNA intercalators Measured in Biochemical System Using Plate Reader - 2117-02_Inhibitor_Dose_CherryPick_Activity_Set2 [AID504727, Type: confirmatory]LANA [Human herpesvirus 8] [gi:312275222]
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7
[SID14723512]
Potency 2.3778qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
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8
[SID14723512]
IC50 4.281Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase [AID2755, Type: confirmatory]Beta lactamase [Pseudomonas aeruginosa] [gi:114881106]
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9
[SID14723512]
AC50_uM 4.985C-LANA FP assay Measured in Biochemical System Using Plate Reader - 2117-01_Inhibitor_Dose_CherryPick_Activity [AID504725, Type: confirmatory]LANA [Human herpesvirus 8] [gi:312275222]
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10
[SID14723512]
Potency 5.7988qHTS Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101: Hit Validation [AID651600, Type: confirmatory]tumor susceptibility gene 101 protein [Homo sapiens] [gi:5454140]
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11
[SID14723512]
Potency 5.8048A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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12
[SID14723512]
EC50 6.261Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity [AID1902, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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13
[SID14723512]
EC50 6.814Luminescence Microorganism-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to SK(-)GAS Group A Streptococcus [AID1900, Type: confirmatory]
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14
[SID14723512]
IC50 9.056Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) [AID588341, Type: confirmatory]Beta lactamase [Pseudomonas aeruginosa] [gi:114881106]
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15
[SID14723512]
Potency 16.3601qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504467, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
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16
[SID14723512]
Potency 18.3564qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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17
[SID14723512]
EC50 21.444Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression [AID1914, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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18
[SID14723512]
Potency 31.6228qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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19
[SID14723512]
EC50_MICROM 33Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically MEP2 based on MLPCN hits [AID2742, Type: confirmatory]MEP2 [Saccharomyces cerevisiae] [gi:1302091]
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20
[SID14723512]
EC50 35.374Luminescence Microorganism-Based Dose Response HTS to Identify Compounds Cytotoxic to Streptococcus [AID1915, Type: confirmatory]
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