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Chlorogenic Acid (CID 1794427) - Compound BioActivity Data
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BioActivity Outcomes:
Active(28)
 
 
Inactive(486)
 
 
Inconclusive(7)
 
 
Unspecified(92)
 
 
Top Targets:
7tm 4(35)
 
 
Esterase lipa..(5)
 
 
CAP ED(5)
 
 
Tryp SPc(5)
 
 
RasGEF(4)
 
 
 
BioAssay Types:
Screening(333)
 
 
 
 
Literature(143)
 
 
 
 
Confirmatory(116)
 
 
 
 
 
BioActivity Types:
Potency(100)
 
 
 
 
 
IC50(42)
 
 
 
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 566    Data Row: 613   Total Pages: 31   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103207024]
IC50 0.2Antihemorrhagic activity in ddY mouse assessed as inhibition of Protobothrops flavoviridis venom-induced hemorrhage incubated with compound for 10 mins measured after 24 hrs [AID592088, Type: Literature]
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2
[SID103207024]
IC50 0.3Inhibition of human recombinant N-terminus His6-tagged AKR1B1 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by spectrometric analysis [AID641085, Type: Literature]Aldose reductase [gi:113596]
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3
[SID103207024]
IC50 0.95Inhibition of Sprague-Dawley rat lens aldose reductase [AID654333, Type: Literature]Aldose reductase [gi:1168407]
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4
[SID103207024]
IC50 1.8Inhibition of human recombinant aldose reductase using D-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured for every 10 secs for 50 mins by spectrophotometry [AID639825, Type: Literature]Aldose reductase [gi:113596]
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5
[SID103207024]
IC50 7.9Inhibition of human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by spectrometric analysis [AID641086, Type: Literature]Aldo-keto reductase family 1 member B10 [gi:322510010]
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6
[SID56463713]
IC50 8.41A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag - Counter Screen [AID2501, Type: confirmatory]
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7
[SID56463713]
Potency 12.5893qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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8
[SID56463713]
IC50 14.67Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents [AID1903, Type: confirmatory]large T antigen [Simian virus 40] [gi:297591903]
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9
[SID56463713]
Potency 17.7828qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
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10
[SID103207024]
IC50 20Antioxidant activity assessed as DPPH free radical scavenging activity after 30 mins in dark by spectrophotometry [AID592361, Type: Literature]
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11
[SID103207024]
IC50 31.3Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 2 [AID93707, Type: Literature]Integrase [gi:82312013]
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12
[SID103207024]
IC50 39.5Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins [AID356132, Type: Literature]
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13
[SID103207024]
IC50 45.5Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins by microplate reader [AID736009, Type: Literature]
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14
[SID103207024]
IC50 45.8Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 1 [AID93705, Type: Literature]Integrase [gi:82312013]
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15
[SID103207024]
IC50 45.8Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transfer [AID91426, Type: Literature]Integrase [gi:82312013]
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16
[SID103207024]
IC50 375Inhibition of HDAC in human Hela cells nuclear extracts by fluorimetric assay [AID447579, Type: Literature]
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17
[SID103207024]
Antioxidant activity assessed as DPPH radical scavenging activity by UV-visible spectrophotometry [AID449328, Type: Literature]
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18
[SID103207024]
Immunomodulatory activity in phytochemagglutininin-stimulatedHMNC assessed as IFN-gamma production at 10 ug/mL after 3 days by EIA realtive to control [AID378768, Type: Literature]
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19
[SID103207024]
Growth inhibition of BALB/c mouse cloned 3T3/A31 cells at 100 ug/mL after 72 hrs by nigrosin assay [AID379093, Type: Literature]
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20
[SID103207024]
Antiobesity activity against high-fat diet fed ICR mouse assessed as decrease in plasma triglyceride level after 4 weeks relative to high-fat diet fed group [AID580004, Type: Literature]
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