Bookmark and Share
SMR001317659 (CID 17757146) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(57)
 
 
Inactive(398)
 
 
Inconclusive(22)
 
 
Unspecified(14)
 
 
Top Targets:
7tm 4(27)
 
 
ABCC CFTR1(4)
 
 
 
Troponin(4)
 
 
RasGEF(4)
 
 
Peptidase C48(4)
 
 
BioAssay Types:
Screening(292)
 
 
 
 
 
Confirmatory(150)
 
 
 
 
 
Literature(36)
 
 
 
 
BioActivity Types:
Potency(110)
 
 
 
 
 
IC50(21)
 
 
 
AC50(3)
 
 
 
EC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 420    Data Row: 491   Total Pages: 25   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103560882]
IC50 0.0067Inhibition of human PDE4A by IMAP fluorescence polarization technology [AID425676, Type: Literature]cAMP-specific 3',5'-cyclic phosphodiesterase 4A [gi:116242706]
View
2
[SID103560882]
IC50 0.0129Inhibition of PDE4A1A [AID425683, Type: Literature]
View
3
[SID165222633]
AbsAC35_uM 0.0163Luminescence cell-based Retest at Dose assay to determine EWS/Fli1 dependent A673 mammalian cell cytotoxity Measured in Cell-Based System Using Plate Reader - 7014-03_Inhibitor_Dose_DryPowder_Activity [AID743478, Type: confirmatory]
View
4
[SID103560882]
EC50 0.0187Inhibition of PDE4 expressed in HEK293 cells coexpressing G-protein coupled receptor and cyclic nucleotide gated ion channel by fluorescence assay [AID425694, Type: Literature]
View
5
[SID165222633]
AbsAC35_uM 0.0226Luminescence cell-based Retest at Dose assay to determine EWS/Fli1 dependent TC71 mammalian cell cytotoxity Measured in Cell-Based System Using Plate Reader - 7014-04_Inhibitor_Dose_DryPowder_Activity [AID743477, Type: confirmatory]
View
6
[SID164339422]
AbsAC35_uM 0.0235Luminescence cell-based Retest at Dose assay to determine EWS/Fli1 dependent A673 mammalian cell cytotoxity Measured in Cell-Based System Using Plate Reader - 7014-03_Inhibitor_Dose_DryPowder_Activity [AID743478, Type: confirmatory]
View
7
[SID164339422]
AbsAC35_uM 0.0276Luminescence cell-based Retest at Dose assay to determine EWS/Fli1 dependent TC71 mammalian cell cytotoxity Measured in Cell-Based System Using Plate Reader - 7014-04_Inhibitor_Dose_DryPowder_Activity [AID743477, Type: confirmatory]
View
8
[SID165222633]
AbsAC35_uM 0.0319Luminescence Cell-Based Primary HTS to identify inhibitors of the oncoprotein EWS/Fli transcriptional activity Measured in Cell-Based System Using Plate Reader - 7014-01_Inhibitor_Dose_DryPowder_Activity [AID743479, Type: confirmatory]
View
9
[SID103560882]
IC50 0.0372Inhibition of PDE4B2 [AID425685, Type: Literature]
View
10
[SID103560882]
IC50 0.0482Inhibition of PDE4B1 [AID425684, Type: Literature]
View
11
[SID103560882]
IC50 0.0492Inhibition of PDE4D2 [AID425687, Type: Literature]
View
12
[SID165222633]
AbsAC35_uM 0.123A549 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-06_Inhibitor_Dose_DryPowder_Activity_Set12 [AID743472, Type: confirmatory]
View
13
[SID164339422]
AbsAC35_uM 0.192A549 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-06_Inhibitor_Dose_DryPowder_Activity_Set12 [AID743472, Type: confirmatory]
View
14
[SID103560882]
IC50 0.452Inhibition of PDE4C1 [AID425686, Type: Literature]
View
15
[SID99495582]
AbsAC40_uM 0.564Luminescent GLuc Reporter Gene Assay Primary HTS to Identify Small Molecule Activator of Glucose Dependent Insulin Secretion Measured in Cell-Based System Using Plate Reader - 7055-01_Activator_Dose_CherryPick_Activity_Set2 [AID977607, Type: confirmatory]
View
16
[SID85146114]
IC50_Mean 0.65Dose response counterscreen of uHTS chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation in a HEK-293T cell line using a luminescence assay [AID489041, Type: confirmatory]
View
17
[SID103560882]
IC50 0.72Inhibition of PDE3B [AID425682, Type: Literature]
View
18
[SID103560882]
IC50 0.823Inhibition of PDE10A1 [AID425675, Type: Literature]
View
19
[SID85146114]
Potency 1.636qHTS of GLP-1 Receptor Agonists: Hit Validation [AID743262, Type: confirmatory]glp-1 receptor, partial [Homo sapiens] [gi:1724069]
View
20
[SID103560882]
IC50 1.7Inhibition of PDE3A [AID425681, Type: Literature]
View