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1,5-dideoxy-1,5-iminogalactitol (CID 176077) - Compound BioActivity Data
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BioActivity Outcomes:
Active(18)
 
 
Inactive(95)
 
 
Inconclusive(6)
 
 
Unspecified(50)
 
 
Top Targets:
p450(9)
 
 
PLN02808(8)
 
 
 
 
GH31 MGAM SI..(6)
 
 
 
 
HSD10-like SD..(4)
 
 
Glyco hydro 3..(3)
 
 
BioAssay Types:
Confirmatory(97)
 
 
 
 
 
Literature(61)
 
 
 
Screening(1)
 
 
BioActivity Types:
Potency(76)
 
 
 
 
IC50(17)
 
 
 
Ki(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 159    Data Row: 169   Total Pages: 9   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103329495]
IC50 0.003Inhibition of coffee bean alpha-galactosidase assessed as p-nitrophenol release at pH 6.5 by spectrometric analysis [AID488404, Type: Literature]Alpha-galactosidase [gi:2492782]
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2
[SID103329495]
IC50 0.003Inhibitory concentration against alpha-galactosidase of coffee bean [AID241236, Type: Literature]
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3
[SID103329495]
Ki 0.013Inhibition of alpha-galactosidase green coffee beans [AID489426, Type: Literature]Alpha-galactosidase [gi:2492782]
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4
[SID103329495]
IC50 0.07Inhibition of human lysosome alpha-galactosidase assessed as p-nitrophenol release by spectrometric analysis [AID488405, Type: Literature]Alpha-galactosidase A [gi:113499]
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5
[SID103329495]
IC50 0.07Inhibitory concentration against human alpha-galactosidase [AID240937, Type: Literature]Alpha-galactosidase A [gi:113499]
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6
[SID11114003]
Potency 0.0823qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen [AID2100, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
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7
[SID103329495]
IC50 0.26Inhibition of sucrase by HPLC [AID466667, Type: Literature]
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8
[SID11114003]
Potency 1.422qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease: Primary Screen Confirmation [AID2590, Type: confirmatory]glucocerebrosidase [Homo sapiens] [gi:496369]
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9
[SID11114003]
Potency 1.422qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease: Hit Validation [AID2671, Type: confirmatory]glucocerebrosidase [Homo sapiens] [gi:496369]
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10
[SID103329495]
IC50 1.5Inhibition of maltase by HPLC [AID466668, Type: Literature]
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11
[SID103329495]
IC50 1.8Inhibitory concentration against alpha-galactosidase of Aspergillus niger [AID241411, Type: Literature]Alpha-galactosidase C [gi:24636246]
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12
[SID11114003]
Potency 5.0119qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease [AID2101, Type: confirmatory]glucocerebrosidase [Homo sapiens] [gi:496369]
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13
[SID103329495]
IC50 6Inhibition of lysosomal alpha-glucosidase by HPLC [AID466672, Type: Literature]
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14
[SID103329495]
IC50 10Inhibition of glycogen glycogen de-branching enzyme by HPLC [AID466673, Type: Literature]
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15
[SID11114003]
Potency 10qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate [AID2112, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
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16
[SID103329495]
Ki 12.5Inhibition of Agrobacterium sp. beta-galactosidase [AID263088, Type: Literature]
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17
[SID103329495]
Ki 13Inhibition of Escherichia coli beta-galactosidase [AID489425, Type: Literature]
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18
[SID103329495]
IC50 24Inhibitory concentration against beta-galactosidase of rat [AID240929, Type: Literature]
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19
[SID103329495]
IC50 50Inhibition of lactase by HPLC [AID466669, Type: Literature]
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20
[SID103329495]
IC50 72Inhibition of rat intestinal lactase assessed as p-nitrophenol release by spectrometric analysis [AID488407, Type: Literature]Lactase-phlorizin hydrolase [gi:6648054]
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