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BioActivity Data for Compound Ethylene Glycol (CID 174)

BioActivity Outcomes:
Active(2)
 
 
Inactive(708)
 
 
Inconclusive(16)
 
 
Unspecified(384)
 
 
Top Targets:
7tm 4(58)
 
 
 
NR LBD PPAR(21)
 
 
 
NR LBD ER(18)
 
 
 
 
NR LBD AR(17)
 
 
 
 
p450(14)
 
 
 
BioAssay Types:
Confirmatory(485)
 
 
 
 
Screening(263)
 
 
 
Summary(48)
 
 
 
Literature(24)
 
 
 
BioAssay Categories:
In vitro(132)
 
 
In vivo(252)
 
 
 
 
Biochemical(220)
 
 
 
Toxicity(293)
 
 
 
 
ADME(6)
 
 
Cell-based(163)
 
 
 
 
Organism-base..(8)
 
 
BioActivity Types:
Potency(360)
 
 
 
 
IC50(123)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 967    Data Row: 1110   Total Pages: 56   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID91222]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Colon Carcinoma 38 (subcutaneous) in B6C3F1 mice [AID214, Type: other]
View
2
[SID85272555]
Identification of VIF Inhibitors Measured in Cell-Based System Using Imaging - 2108-01_Inhibitor_SinglePoint_HTS_Activity [AID602346, Type: screening]Vif [Human immunodeficiency virus 1] [gi:9629361]
View
3
[SID103601826]
CC50 221Cytotoxicity against human HL60 cells in presence of RPMI1640 containing 10% fetal bovine serum by trypan blue exclusion test [AID382489, Type: Literature]
View
4
[SID103601826]
CC50 385Cytotoxicity against human HSC4 cells by MTT method [AID382488, Type: Literature]
View
5
[SID103601826]
CC50 400Cytotoxicity against human gingival fibroblast by MTT method [AID382490, Type: Literature]
View
6
[SID103601826]
CC50 400Cytotoxicity against human pulp cells by MTT method [AID382491, Type: Literature]
View
7
[SID103601826]
CC50 400Cytotoxicity against human periodontal ligament fibroblast by MTT method [AID382492, Type: Literature]
View
8
[SID103601826]
CC50 400Cytotoxicity against human HSC2 by MTT method [AID382487, Type: Literature]
View
9
[SID103601826]
Binding affinity to beta cyclodextrin [AID346025, Type: Literature]
View
10
[SID103601826]
IC50 DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine) [AID625270, Type: confirmatory]Histamine H2 receptor [gi:123120]
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11
[SID103601826]
IC50 DRUGMATRIX: HMG-CoA Reductase enzyme inhibition (substrate: [14C]HMG-CoA) [AID625271, Type: confirmatory]3-hydroxy-3-methylglutaryl-coenzyme A reductase [gi:123343]
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12
[SID103601826]
IC50 DRUGMATRIX: Insulin radioligand binding (ligand: [125I] Insulin) [AID625273, Type: confirmatory]Insulin receptor [gi:124531]
View
13
[SID103601826]
IC50 DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625185, Type: confirmatory]Tyrosine-protein kinase Fyn [gi:125370]
View
14
[SID103601826]
IC50 DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625187, Type: confirmatory]Tyrosine-protein kinase Lck [gi:125474]
View
15
[SID103601826]
IC50 DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) [AID625146, Type: confirmatory]Arachidonate 15-lipoxygenase [gi:126397]
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16
[SID103601826]
IC50 DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P) [AID625226, Type: confirmatory]Substance-P receptor [gi:128359]
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17
[SID103601826]
IC50 DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55) [AID625207, Type: confirmatory]Sodium-dependent noradrenaline transporter [gi:128616]
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18
[SID103601826]
DRUGMATRIX: Neuropeptide Y Y1 radioligand binding (ligand: [125I] Peptide YY) [AID625156, Type: other]Neuropeptide Y receptor type 1 [gi:128997]
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19
[SID103601826]
IC50 DRUGMATRIX: Platelet Activating Factor (PAF) radioligand binding (ligand: [3H] PAF) [AID625168, Type: confirmatory]Platelet-activating factor receptor [gi:129557]
View
20
[SID103601826]
IC50 DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX) [AID625194, Type: confirmatory]Adenosine receptor A1 [gi:231473]
View