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BioActivity Data for Compound Ethylene Glycol (CID 174)

BioActivity Outcomes:
Active(2)
 
 
Inactive(739)
 
 
Inconclusive(17)
 
 
Unspecified(384)
 
 
Top Targets:
7tm 4(57)
 
 
 
NR LBD PPAR(21)
 
 
 
NR LBD ER(18)
 
 
 
 
NR LBD AR(17)
 
 
 
 
p450(14)
 
 
 
BioAssay Types:
Confirmatory(506)
 
 
 
 
Screening(263)
 
 
 
Summary(58)
 
 
 
Literature(24)
 
 
 
BioAssay Categories:
In vitro(132)
 
 
In vivo(252)
 
 
 
 
Biochemical(220)
 
 
 
Toxicity(293)
 
 
 
 
ADME(6)
 
 
Cell-based(163)
 
 
 
 
Organism-base..(8)
 
 
BioActivity Types:
Potency(391)
 
 
 
 
IC50(123)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 984    Data Row: 1142   Total Pages: 58   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID91222]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Colon Carcinoma 38 (subcutaneous) in B6C3F1 mice [AID214, Type: other]
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2
[SID85272555]
Identification of VIF Inhibitors Measured in Cell-Based System Using Imaging - 2108-01_Inhibitor_SinglePoint_HTS_Activity [AID602346, Type: screening]Vif [Human immunodeficiency virus 1] [gi:9629361]
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3
[SID103601826]
CC50 221Cytotoxicity against human HL60 cells in presence of RPMI1640 containing 10% fetal bovine serum by trypan blue exclusion test [AID382489, Type: Literature]
View
4
[SID103601826]
CC50 385Cytotoxicity against human HSC4 cells by MTT method [AID382488, Type: Literature]
View
5
[SID103601826]
CC50 400Cytotoxicity against human HSC2 by MTT method [AID382487, Type: Literature]
View
6
[SID103601826]
CC50 400Cytotoxicity against human gingival fibroblast by MTT method [AID382490, Type: Literature]
View
7
[SID103601826]
CC50 400Cytotoxicity against human pulp cells by MTT method [AID382491, Type: Literature]
View
8
[SID103601826]
CC50 400Cytotoxicity against human periodontal ligament fibroblast by MTT method [AID382492, Type: Literature]
View
9
[SID103601826]
IC50 DRUGMATRIX: Nicotinic Acetylcholine radioligand binding (ligand: [125I] Epibatidine) [AID625158, Type: confirmatory]
View
10
[SID103601826]
DRUGMATRIX: Phorbol Ester radioligand binding (ligand: [3H] PDBu) [AID625164, Type: other]
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11
[SID103601826]
IC50 DRUGMATRIX: Phosphodiesterase PDE3 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625165, Type: confirmatory]
View
12
[SID103601826]
Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset [AID588209, Type: Literature]
View
13
[SID103601826]
Human drug-induced liver injury (DILI) modelling dataset from Ekins et al [AID588210, Type: Literature]
View
14
[SID103601826]
Binding affinity to beta cyclodextrin [AID346025, Type: Literature]
View
15
[SID103601826]
DrugMatrix: Regimen: Daily Repeat; Time: 3 day; Dose: Low; Vehicle: 100 % water; Route: oral gavage | Dataset: Hematology; Assay: MONOLE (Monocytes/Leukocytes); Study_ID: S011211 [AID927585, Type: other]
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16
[SID103601826]
DrugMatrix: Regimen: Daily Repeat; Time: 3 day; Dose: Low; Vehicle: 100 % water; Route: oral gavage | Dataset: Hematology; Assay: RBCNUC (Nucleated Erythrocytes); Study_ID: S011211 [AID927586, Type: other]
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17
[SID103601826]
DrugMatrix: Regimen: Daily Repeat; Time: 3 day; Dose: Low; Vehicle: 100 % water; Route: oral gavage | Dataset: Hematology; Assay: MCV (Ery. Mean Corpuscular Volume); Study_ID: S011211 [AID927587, Type: other]
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18
[SID103601826]
DrugMatrix: Regimen: Daily Repeat; Time: 3 day; Dose: Low; Vehicle: 100 % water; Route: oral gavage | Dataset: Hematology; Assay: NEUTLE (Neutrophils/Leukocytes); Study_ID: S011211 [AID927588, Type: other]
View
19
[SID103601826]
DrugMatrix: Regimen: Daily Repeat; Time: 5 day; Dose: Low; Vehicle: 100 % water; Route: oral gavage | Dataset: Hematology; Assay: NEUTLE (Neutrophils/Leukocytes); Study_ID: S011211 [AID928985, Type: other]
View
20
[SID432587]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Nontumored Animals (Toxicity Test) in B6D2F1 (BDF1) mice [AID186, Type: other]
View