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Benzophenoneidum (CID 17170) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(151)
 
 
Inactive(139)
 
 
Inconclusive(216)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
 
NR LBD ER(16)
 
 
 
 
NR LBD AR(16)
 
 
 
 
NR LBD VDR(10)
 
 
 
 
NR LBD TR(10)
 
 
 
 
BioAssay Types:
Confirmatory(274)
 
 
 
 
Summary(48)
 
 
 
 
Literature(1)
 
 
BioActivity Types:
Potency(273)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 250    Data Row: 509   Total Pages: 11   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144213319]
AhR Potency (uM) 0.74035qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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2
[SID144213319]
Potency-Replicate_1 1.8764qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway [AID743223, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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3
[SID144209535]
Potency-Replicate_1 2.404qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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4
[SID144209535]
AhR Potency (uM) 3.39572qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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5
[SID144209535]
Potency-Replicate_1 3.8101qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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6
[SID144209535]
Potency-Replicate_1 4.275qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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7
[SID144209535]
Ratio Potency (uM) 4.98423qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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8
[SID17390034]
Potency 5.308qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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9
[SID144209535]
Potency-Replicate_1 5.3818qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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10
[SID144213319]
Potency-Replicate_1 5.8808qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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11
[SID144213319]
Ratio Potency (uM) 7.12476qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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12
[SID144213319]
Potency-Replicate_1 7.4035qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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13
[SID144213319]
Potency-Replicate_1 8.3069qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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14
[SID144209535]
TR Potency (uM) 9.57043qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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15
[SID144213319]
Potency-Replicate_1 11.7337qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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16
[SID144213319]
Potency-Replicate_1 11.7337qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
17
[SID17390034]
Potency 14.1254qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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18
[SID17390034]
Potency 14.1254qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway [AID651751, Type: confirmatory]pregnane X receptor [Rattus norvegicus] [gi:5702233]
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19
[SID144213319]
Potency-Replicate_1 14.7719qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
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20
[SID17390034]
Potency 15.8489qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
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21
[SID17390034]
Potency 15.8489MultiTox-Fluor Cytotoxicity Assay - LYMP1-002 - Dead Cells [AID960, Type: confirmatory]
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22
[SID144213319]
Potency-Replicate_1 23.4119qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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23
[SID17390034]
Potency 25.1189Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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24
[SID144213319]
Potency-Replicate_1 26.2686qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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25
[SID144213319]
Ratio Potency (uM) 26.5054qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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26
[SID144209535]
Potency-Replicate_1 26.9731qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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27
[SID144209535]
Potency-Replicate_1 30.2644qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
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28
[SID17390034]
Potency 31.6228Cell Viability - LYMP2-001 [AID921, Type: confirmatory]
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29
[SID144209535]
Potency-Replicate_1 34.2375qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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30
[SID144213319]
Potency-Replicate_1 37.4398qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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31
[SID144213319]
Potency-Replicate_1 37.4398qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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32
[SID17390034]
Potency 39.8107MultiTox-Fluor Cytotoxicity Assay - LYMP1-001 - Dead Cells [AID946, Type: confirmatory]
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33
[SID17390034]
Potency 39.8107Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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34
[SID17390034]
Potency 39.8107Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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35
[SID17390034]
Potency 39.8107Cell Viability - LYMP2-020 [AID986, Type: confirmatory]
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36
[SID17390034]
Potency 39.8107Cell Viability - LYMP2-012 [AID982, Type: confirmatory]
View
37
[SID17390034]
Potency 39.8107Cell Viability - LYMP2-014 [AID983, Type: confirmatory]
View
38
[SID144213319]
Potency-Replicate_1 42.0082qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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39
[SID144209535]
Ratio Potency (uM) 44.422qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
View
40
[SID144213319]
Potency-Replicate_1 46.7129qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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41
[SID144213319]
Potency-Replicate_1 46.7129qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
42
[SID144213319]
Ratio Potency (uM) 46.7129qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
View
43
[SID144213319]
Potency-Replicate_1 47.1339qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743215, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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44
[SID144209535]
Potency-Replicate_1 47.9658qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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45
[SID144209535]
Potency-Replicate_1 47.9658qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
View
46
[SID17390034]
Potency 50.1187MultiTox-Fluor Cytotoxicity Assay - LYMP1-003 - Dead Cells [AID961, Type: confirmatory]
View
47
[SID144213319]
Potency-Replicate_1 52.4127qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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48
[SID144209535]
Potency-Replicate_1 53.8185qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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49
[SID144209535]
Potency-Replicate_1 60.3853qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
View
50
[SID144213319]
Potency-Replicate_1 65.9837qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View