Benzophenoneidum (CID 17170) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(112)
 
 
Inactive(75)
 
 
Inconclusive(138)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(5)
 
 
 
 
NR LBD TR(4)
 
 
P53(3)
 
 
NR LBD ROR li..(3)
 
 
 
NR LBD VDR(2)
 
 
BioAssay Types:
Confirmatory(141)
 
 
 
 
Literature(1)
 
 
BioActivity Types:
Potency(105)
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 158    Data Row: 328   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17390034]
Potency 5.308qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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2
[SID17390034]
Potency 5.308qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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3
[SID17390034]
Potency 5.308qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View
4
[SID17390034]
Potency 5.308qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View
5
[SID17390034]
Potency 5.308qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View
6
[SID17390034]
Potency 14.1254qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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7
[SID17390034]
Potency 14.1254qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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8
[SID17390034]
Potency 14.1254qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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9
[SID17390034]
Potency 14.1254qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
10
[SID17390034]
Potency 14.1254qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway [AID651751, Type: confirmatory]pregnane X receptor [Rattus norvegicus] [gi:5702233]
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11
[SID17390034]
Potency 15.8489MultiTox-Fluor Cytotoxicity Assay - LYMP1-002 - Dead Cells [AID960, Type: confirmatory]
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12
[SID17390034]
Potency 15.8489qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
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13
[SID17390034]
Potency 15.8489qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
View
14
[SID17390034]
Potency 15.8489qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
View
15
[SID17390034]
Potency 15.8489qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
View
16
[SID17390034]
Potency 15.8489qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
View
17
[SID17390034]
Potency 25.1189Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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18
[SID17390034]
Potency 31.6228Cell Viability - LYMP2-001 [AID921, Type: confirmatory]
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19
[SID17390034]
Potency 39.8107Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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20
[SID17390034]
Potency 39.8107Cell Viability - LYMP2-012 [AID982, Type: confirmatory]
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21
[SID17390034]
Potency 39.8107Cell Viability - LYMP2-014 [AID983, Type: confirmatory]
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22
[SID17390034]
Potency 39.8107Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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23
[SID17390034]
Potency 39.8107Cell Viability - LYMP2-020 [AID986, Type: confirmatory]
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24
[SID17390034]
Potency 39.8107MultiTox-Fluor Cytotoxicity Assay - LYMP1-001 - Dead Cells [AID946, Type: confirmatory]
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25
[SID17390034]
Potency 50.1187MultiTox-Fluor Cytotoxicity Assay - LYMP1-003 - Dead Cells [AID961, Type: confirmatory]
View
26
[SID17390034]
Potency 66.8242qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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27
[SID17390034]
Potency 66.8242qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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28
[SID17390034]
Potency 66.8242qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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29
[SID17390034]
 Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_78, Type: other]
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30
[SID17390034]
 Cell Viability - HepG2 [AID433, Type: confirmatory]
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31
[SID17390034]
 Cell Viability - H-4-II-E [AID543, Type: confirmatory]
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32
[SID17390034]
 Cell Viability - SH-SY5Y [AID544, Type: confirmatory]
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33
[SID17390034]
 Cell Viability - N2a [AID540, Type: confirmatory]
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34
[SID48413243]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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35
[SID48413243]
 DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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36
[SID48413243]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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37
[SID48413243]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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38
[SID48413243]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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39
[SID17390034]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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40
[SID17390034]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
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41
[SID17390034]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
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42
[SID17390034]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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43
[SID17390034]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_5, Type: other]
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44
[SID17390034]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
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45
[SID17390034]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
View
46
[SID17390034]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_8, Type: other]
View
47
[SID17390034]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_11, Type: other]
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48
[SID17390034]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_14, Type: other]
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49
[SID17390034]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_23, Type: other]
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50
[SID17390034]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_24, Type: other]
View