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2-(allylamino)-3-chloronaphthoquinone (CID 1716436) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(89)
 
 
Inactive(661)
 
 
Inconclusive(30)
 
 
Unspecified(11)
 
 
Top Targets:
7TM GPCR Srx(24)
 
 
 
DUF3371(20)
 
 
 
7TM GPCR Srsx(20)
 
 
 
 
Peptidase C48(11)
 
 
 
Bcl-2 like(11)
 
 
BioAssay Types:
Screening(487)
 
 
 
 
 
Confirmatory(269)
 
 
 
 
 
Literature(21)
 
 
 
BioActivity Types:
Potency(150)
 
 
 
 
 
AC50(49)
 
 
 
IC50(46)
 
 
 
 
EC50(10)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 717    Data Row: 791   Total Pages: 40   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134418986]
AbsAC40_uM 0.276qPCR Assay for MITF Expression Measured in Cell-Based System Using RT-PCR - 2084-05_Inhibitor_Dose_DryPowder_Activity [AID651773, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
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2
[SID134418986]
AC50_uM 0.735MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set7 [AID624426, Type: confirmatory]
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3
[SID134418986]
AbsAC40_uM 0.764qPCR Assay for MLANA Expression Measured in Cell-Based System Using RT-PCR - 2084-13_Inhibitor_Dose_DryPowder_Activity [AID651795, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
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4
[SID134418986]
AC50_uM 0.799MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set5 [AID624363, Type: confirmatory]
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5
[SID121269797]
AC50_uM 0.905MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity [AID540348, Type: confirmatory]
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6
[SID134418986]
AbsAC40_uM 0.943qPCR Assay for TRPM1 Expression Measured in Cell-Based System Using RT-PCR - 2084-09_Inhibitor_Dose_DryPowder_Activity [AID651770, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
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7
[SID134418986]
AbsAC40_uM 1qPCR Assay for DCT Expression Measured in Cell-Based System Using RT-PCR - 2084-12_Inhibitor_Dose_DryPowder_Activity [AID651771, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
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8
[SID134418986]
AbsAC40_uM 1.46qPCR Assay for CDK2 Expression Measured in Cell-Based System Using RT-PCR - 2084-11_Inhibitor_Dose_DryPowder_Activity [AID651772, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
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9
[SID134418986]
AC50_uM 1.56MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set6 [AID624440, Type: confirmatory]
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10
[SID134418986]
AC50_uM 1.67MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set4 [AID624316, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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11
[SID134418986]
AC50_uM 1.7MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set5 [AID624427, Type: confirmatory]
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12
[SID134970398]
AC50_uM 1.88MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set5 [AID624363, Type: confirmatory]
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13
[SID134970398]
AC50_uM 1.94MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624290, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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14
[SID134970398]
AC50_uM 2.18MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set4 [AID624316, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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15
[SID134418986]
AC50_uM 2.22MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624290, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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16
[SID22416871]
Potency 2.9362Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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17
[SID22416871]
IC50_Mean 3.62Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay [AID488901, Type: confirmatory]caspase-3 preproprotein [Homo sapiens] [gi:14790119]
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18
[SID134418986]
AC50_uM 3.82MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set6 [AID624429, Type: confirmatory]
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19
[SID22416871]
AC50_uM 4.061MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_DoseNoFile_CherryPick_Activity_Set3 [AID493073, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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20
[SID22416871]
AC50_uM 4.061MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_DoseNoFile_CherryPick_Activity_Set4 [AID493102, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
View