thioflavin T (CID 16953) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(8)
 
 
Inactive(1)
 
 
Unspecified(11)
 
 
Top Targets:
APP N(2)
 
 
BioAssay Types:
Literature(14)
 
 
 
 
BioActivity Types:
Ki(6)
 
 
Kd(2)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 20    Data Row: 20   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103513493]
Kd 0.56Binding affinity to beta amyloid protein 1-40 by fluorescence titration [AID298192, Type: Literature]
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2
[SID103513493]
Kd 2.3Binding affinity to amyloid beta (1 to 40) [AID533777, Type: Literature]
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3
[SID540039]
 NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
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4
[SID540039]
 NCI Yeast Anticancer Drug Screen. Data for the bub3 strain [AID167, Type: other]
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5
[SID540039]
 NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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6
[SID540039]
 NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
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7
[SID540039]
 NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
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8
[SID540039]
 NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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9
[SID103513493]
Ki 1Displacement of [125I]6-iodo-4'-dimethyaminofl avone from beta amyloid (1-42) protein aggregates [AID282857, Type: Literature]Amyloid beta A4 protein [gi:112927]
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10
[SID103513493]
Ki 1Displacement of [125I]6-iodo-4'-dimethyaminofl avone from beta amyloid (1-42) protein aggregates [AID282857, Type: Literature]Amyloid beta A4 protein [gi:112927]
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11
[SID103513493]
Ki 1Displacement of [125I]6-iodo-4'-dimethyaminofl avone from beta amyloid (1-42) protein aggregates [AID282857, Type: Literature]Amyloid beta A4 protein [gi:112927]
View
12
[SID103513493]
Ki 1Displacement of [125I]6-iodo-4'-dimethyaminofl avone from beta amyloid (1-40) protein aggregates [AID282856, Type: Literature]Amyloid beta A4 protein [gi:112927]
View
13
[SID103513493]
Ki 1Displacement of [125I]6-iodo-4'-dimethyaminofl avone from beta amyloid (1-40) protein aggregates [AID282856, Type: Literature]Amyloid beta A4 protein [gi:112927]
View
14
[SID103513493]
Ki 1Displacement of [125I]6-iodo-4'-dimethyaminofl avone from beta amyloid (1-40) protein aggregates [AID282856, Type: Literature]Amyloid beta A4 protein [gi:112927]
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15
[SID103513493]
Ki 1Displacement of [125I-N-Methyl-4-(4-bromoanilino)phthalimide from beta-amyloid plaques isolated from Alzheimer's disease patient brain [AID459782, Type: Literature]
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16
[SID103513493]
Ki 1Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assay [AID445593, Type: Literature]
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17
[SID103513493]
Ki 10Displacement of [125I]DMIC from amyloid beta 1-42 aggregates [AID300748, Type: Literature]
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18
[SID103513493]
Ki 10Displacement of [125I](E)-3-(4-(Dimethylamino-phenyl)-1-(4-iodophenyl)prop-2-en-1-one from beta amyloid(1-42) aggregates [AID301579, Type: Literature]
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19
[SID103513493]
 Binding affinity to human beta amyloid protein 1-40 from Alzheimers disease patient [AID321392, Type: Literature]
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20
[SID103513493]
 Binding affinity to human beta amyloid protein 1-28 from Alzheimers disease patient [AID321393, Type: Literature]
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21
[SID103513493]
 Binding affinity to human insulin fibril by fluorescence intensity assay [AID634859, Type: Literature]
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22
[SID103513493]
 Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assay [AID634860, Type: Literature]
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23
[SID103513493]
 Binding affinity to human alpha-synphilin fibril by fluorescence intensity assay [AID634858, Type: Literature]
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24
[SID103513493]
 Binding affinity to amyloid beta plaque in mouse brain tissue by thioflavin staining-based fluorescence analysis [AID662425, Type: Literature]
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