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ethoxazene (CID 16837) - Compound BioActivity Data
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BioActivity Outcomes:
Active(19)
 
 
Inactive(96)
 
 
Inconclusive(46)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
 
NR LBD TR(5)
 
 
 
 
NR LBD GR(4)
 
 
 
Bromo ALL-1(3)
 
 
 
BioAssay Types:
Confirmatory(81)
 
 
 
 
Literature(65)
 
 
 
 
 
Summary(15)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(93)
 
 
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 101    Data Row: 164   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144205444]
Potency-Replicate_1 0.1679qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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2
[SID29216232]
Potency 0.2031Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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3
[SID144205444]
Potency-Replicate_1 0.2113qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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4
[SID144205444]
ATAD5 Potency (uM) 0.237101qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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5
[SID144205444]
Potency-Replicate_1 0.4731qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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6
[SID144205444]
Potency-Replicate_1 0.9439qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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7
[SID144205444]
AhR Potency (uM) 0.999848qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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8
[SID144205444]
Potency-Replicate_1 1.6785qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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9
[SID144205444]
Potency-Replicate_1 2.371qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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10
[SID144205444]
Ratio Potency (uM) 2.70015qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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11
[SID160687840]
EC50 4.76Inhibition of RML prion protein infected in mouse dividing ScN2a-cl3 cells expressing full length mouse PrP assessed as reduction of PrPsc level after 5 days by ELISA [AID1057862, Type: Literature]
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12
[SID29216232]
Potency 8.9125qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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13
[SID29216232]
Potency 10VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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14
[SID144205444]
Potency-Replicate_1 10.5909qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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15
[SID144205444]
Potency-Replicate_1 11.8832qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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16
[SID144205444]
Potency-Replicate_1 14.9601qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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17
[SID144205444]
Potency-Replicate_1 21.1317qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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18
[SID144205444]
Potency-Replicate_1 21.1317qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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19
[SID144205444]
Potency-Replicate_1 23.7101qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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20
[SID160687840]
LC50 10Cytotoxicity against mouse dividing ScN2a-cl3 cells assessed as cell viability after 5 days by calcein-AM staining-based fluorescence assay [AID1057863, Type: Literature]
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