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NCGC00095212-01 (CID 16757864) - Compound BioActivity Data
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BioActivity Outcomes:
Active(18)
 
 
Inactive(47)
 
 
Inconclusive(9)
 
 
Unspecified(1)
 
 
Top Targets:
PLDc mTdp1 2(3)
 
 
 
TUDOR(3)
 
 
 
HELICc(3)
 
 
 
GH27(2)
 
 
HSD10-like SD..(2)
 
 
BioAssay Types:
Confirmatory(74)
 
 
 
 
 
Screening(1)
 
 
BioActivity Types:
Potency(70)
 
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 71    Data Row: 75   Total Pages: 4   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26749131]
Potency 0.5805qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID26749131]
Potency 0.7943qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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3
[SID26749131]
Potency 0.8199qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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4
[SID26749131]
Potency 2.2387qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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5
[SID26749131]
Potency 4.4668VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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6
[SID26749131]
Potency 4.4668Counterscreen for RECQ1 Inhibitors: ADP Fluorescence Polarization Displacement Assay [AID2711, Type: confirmatory]
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7
[SID26749131]
Potency 4.4668Counterscreen for BLMA Inhibitors: ADP Fluorescence Polarization Displacement Assay [AID2712, Type: confirmatory]
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8
[SID26749131]
Potency 6.3096Quantitative High-Throughput Screen for Regulators of Epigenetic Control [AID1865, Type: confirmatory]
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9
[SID26749131]
Potency 6.3096qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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10
[SID26749131]
Potency 8.9125qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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11
[SID26749131]
Potency 10qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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12
[SID26749131]
Potency 14.1254qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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13
[SID26749131]
Potency 15.8489Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 locus [AID910, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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14
[SID26749131]
Potency 19.9526qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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15
[SID26749131]
Potency 31.6228Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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16
[SID26749131]
Potency 56.2341Inhibitors of USP1/UAF1: Pilot qHTS [AID504865, Type: confirmatory]USP1 protein, partial [Homo sapiens] [gi:118600387]
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17
[SID26749131]
Potency 112.202Confirmation qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2708, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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18
[SID26749131]
Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Modulation of SMN1 Expression [AID1739, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:4507091]
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19
[SID26749131]
Potency Confirmation Concentration-Response Assay for Enhancers of SMN2 Splice Variant Expression [AID1740, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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20
[SID26749131]
Potency 1.2589qHTS Assay for Compounds that Induce Erasure of Genomic Imprints [AID1948, Type: confirmatory]
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