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MLS000882762 (CID 16746500) - Compound BioActivity Data
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BioActivity Outcomes:
Active(7)
 
 
Inactive(565)
 
 
Inconclusive(17)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
7TM GPCR Srsx(12)
 
 
 
G-alpha(7)
 
 
 
Tryp SPc(7)
 
 
 
TRP 2(5)
 
 
BioAssay Types:
Screening(396)
 
 
 
 
Confirmatory(183)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(133)
 
 
 
 
 
IC50(39)
 
 
EC50(5)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 539    Data Row: 590   Total Pages: 12   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26732364]
Potency 10qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction [AID1461, Type: confirmatory]neuropeptide S receptor isoform A [Homo sapiens] [gi:46395496]
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2
[SID26732364]
Potency 14.581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID26732364]
Potency 14.581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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4
[SID26732364]
Potency 25.1189qHTS Assay for Activators of ClpP [AID651965, Type: confirmatory]ClpP [Bacillus subtilis] [gi:2668494]
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5
[SID26732364]
qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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6
[SID26732364]
Single concentration confirmation of chemical inhibitors of B-cell specific antigen receptor-induced NF-kB activation [AID449746, Type: screening]
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7
[SID26732364]
uHTS luminescence assay for the identification of chemical inhibitors of B-cell specific antigen receptor-induced NF-kB activation [AID435022, Type: screening]
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8
[SID26732364]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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9
[SID26732364]
Potency 7.9433qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
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10
[SID26732364]
IC50_Mean 35.7Dose Response selectivity of uHTS chemical inhibitors of B-cell specific antigen receptor-induced NF-kB activation in Jurkat cells using a luminescence assay [AID489006, Type: confirmatory]
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11
[SID26732364]
IC50_Mean 55.5Dose response counterscreen of uHTS chemical inhibitors of B-cell specific antigen receptor-induced NF-kB activation in a HEK-293T cell line using a luminescence assay [AID489022, Type: confirmatory]
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12
[SID26732364]
IC50_Mean 80Dose response confirmation of uHTS of chemical inhibitors of B-cell specific antigen receptor-induced NF-kB activation in a 697B cell line using a luminescence assay [AID489023, Type: confirmatory]
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13
[SID26732364]
IC50_Mean 80Dose response cytotoxicity of uHTS chemical inhibitors of B-cell specific antigen receptor-induced NF-kB activation in a HEK-293T cell line using a luminescence assay [AID489021, Type: confirmatory]
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14
[SID26732364]
Inhibitors of Prion Protein 5' UTR mRNA Measured in Cell-Based System Using Plate Reader - 2078-01_Inhibitor_SinglePoint_HTS_Activity [AID488862, Type: screening]
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15
[SID26732364]
IC50 Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosis [AID488890, Type: confirmatory]
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16
[SID26732364]
IC50 Primary and Confirmatory Screening for Inhibitors of Bacterial Capsule Biogenesis [AID488966, Type: confirmatory]
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17
[SID26732364]
Counterscreen for inhibitors of AddAB: absorbance-based bacterial cell-based high throughput screening assay to identify inhibitors of bacterial viability [AID449728, Type: screening]
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18
[SID26732364]
Potency qHTS Assay for Modulators of miRNAs and/or Inhibitors of miR-21 [AID2289, Type: confirmatory]
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19
[SID26732364]
uHTS identification of small molecules that induce b-cell replication in the MIN-6 cell line [AID2380, Type: screening]
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20
[SID26732364]
IC50 A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) [AID2391, Type: confirmatory]
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21
[SID26732364]
Potency qHTS Assay for Lipid Storage Modulators in Drosophila S3 Cells [AID2685, Type: confirmatory]
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22
[SID26732364]
A yeast HTS for caloric restriction mimetics that inhibit age-related superoxide [AID2690, Type: screening]
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23
[SID26732364]
Luminescence Microorganism Primary HTS to Identify Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301 [AID2716, Type: screening]
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24
[SID26732364]
Luminescence Cell-Based/Microorganism Primary HTS to Identify Inhibitors of T.Cruzi Replication [AID1885, Type: screening]
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25
[SID26732364]
Luminescence Cell-Based Primary HTS to Identify Transcriptional Activators of Hypoxia-Inducible Factor Pathway [AID1910, Type: screening]
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26
[SID26732364]
Conc @ Max Fold Increase A high-throughput screen to identify small molecule compounds that augment HSV replication [AID1956, Type: confirmatory]
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27
[SID26732364]
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity [AID2099, Type: screening]
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28
[SID26732364]
Fluorescence Cell-Free Homogeneous Primary HTS to Identify Inhibitors of the RanGTP-Importin-beta complex [AID2216, Type: screening]
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29
[SID26732364]
Potency qHTS Assay for Modulators of miRNAs and/orActivators of miR-21 [AID2288, Type: confirmatory]
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30
[SID26732364]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - inhibitors [AID1813, Type: screening]
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31
[SID26732364]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
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32
[SID26732364]
IC50 A small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID1850, Type: confirmatory]
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33
[SID26732364]
IC50 A small molecule screen for inhibitors of the PhoP regulon in Salmonella Typhimurium [AID1863, Type: confirmatory]
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34
[SID26732364]
Potency Quantitative High-Throughput Screen for Regulators of Epigenetic Control [AID1865, Type: confirmatory]
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35
[SID26732364]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Polyadenylation [AID1875, Type: screening]
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36
[SID26732364]
MLPCN Ras selective lethality-BJeLR viability [AID1554, Type: screening]
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37
[SID26732364]
IC50 A Cell Based Assay for the Identification of Lead Compounds with Anti-Viral Activity Against West Nile Virus [AID1621, Type: confirmatory]
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38
[SID26732364]
IC50 High Throughput Screen to Identify Inhibitors of Mycobacterium tuberculosis H37Rv [AID1626, Type: confirmatory]
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39
[SID26732364]
High Throughput Imaging Assay for Hepatic Lipid Droplet Formation [AID1656, Type: screening]
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40
[SID26732364]
MLPCN Platelet Activation -Dense Granule Release [AID1663, Type: screening]
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41
[SID26732364]
Profiling compound fluorescence on Avidin Beads with 488 nm excitation and 530 nm emission [AID1775, Type: other]
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42
[SID26732364]
Potency qHTS Assay to Find Inhibitors of Chronic Active B-Cell Receptor Signaling [AID493014, Type: confirmatory]
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43
[SID26732364]
Heat Shock Factor-1 (HSF-1) Measured in Cell-Based System Using Plate Reader - 2038-01_Activator_SinglePoint_HTS_Activity [AID504408, Type: screening]
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44
[SID26732364]
384-well Z-Lyte format Hck-Nef inhibitor HTS run at the PMLSC [AID463187, Type: screening]
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45
[SID26732364]
Phenotypic HTS multiplex for antifungal efflux pump inhibitors [AID485275, Type: screening]
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46
[SID26732364]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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47
[SID26732364]
qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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48
[SID26732364]
qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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49
[SID26732364]
Small Molecules that selectively kill Giardia lamblia: qHTS [AID540267, Type: screening]
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50
[SID26732364]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the GAA850 frataxin (FXN) promoter [AID540364, Type: screening] [geneid:2395]
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