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MLS000911607 (CID 16745791) - Compound BioActivity Data
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BioActivity Outcomes:
Active(26)
 
 
Inactive(566)
 
 
Inconclusive(22)
 
 
Unspecified(5)
 
 
Top Targets:
7tm 4(37)
 
 
G-alpha(8)
 
 
 
Esterase lipa..(8)
 
 
 
Tryp SPc(7)
 
 
Bcl-2 like(5)
 
 
BioAssay Types:
Screening(405)
 
 
 
 
Confirmatory(192)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(134)
 
 
 
 
 
IC50(44)
 
 
 
 
 
EC50(6)
 
 
AC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 551    Data Row: 619   Total Pages: 31   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49828085]
AC50_uM 0.435DiI Quencher Assay Measured in Biochemical System Using Plate Reader - 2085-08_Inhibitor_Dose_CherryPick_Activity [AID540326, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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2
[SID26725570]
IC50 0.954High Throughput Screen to Identify Inhibitors of Mycobacterium tuberculosis H37Rv [AID1626, Type: confirmatory]
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3
[SID26725570]
Potency 5.0119Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1463, Type: confirmatory]
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4
[SID49828085]
IC50_TAG_Mean 6.44Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630, Type: confirmatory]
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5
[SID49828085]
IC50_TAG_Mean 6.44Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630_1, Type: confirmatory]
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6
[SID49828085]
Potency 6.5131qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID26725570]
Potency 8.2753Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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8
[SID49828085]
Potency 9.2qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID26725570]
Potency 9.285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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10
[SID26725570]
Potency 10.3183qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504467, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
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11
[SID49828085]
Potency 19.9526qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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12
[SID49828085]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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13
[SID49828085]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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14
[SID49828085]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH) [AID463082, Type: screening]platelet-activating factor acetylhydrolase precursor [Homo sapiens] [gi:270133071]
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15
[SID26725570]
MLPCN Streptokinase Expression Inhibition [AID1662, Type: screening]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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16
[SID49828085]
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity [AID488896, Type: screening]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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17
[SID49828085]
Single concentration confirmation of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651629, Type: screening]
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18
[SID49828085]
uHTS identification of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651582, Type: screening]
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19
[SID113234704]
Late stage assay provider results from the probe development effort to identify inhibitors of Fam108b: gel-based activity-based protein profiling (ABPP) assay to assess HTS hit compound inhibition and selectivity against a recombinant soluble form of Fam108b in a complex proteome [AID588651, Type: other]
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20
[SID26725570]
IC50 HCS for Compounds that Down-Regulate Insulin Promoter Activity in MIN6 Cells [AID1628, Type: confirmatory]
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