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MLS001045906 (CID 16745609) - Compound BioActivity Data
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BioActivity Outcomes:
Active(9)
 
 
Inactive(611)
 
 
Inconclusive(27)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(37)
 
 
G-alpha(8)
 
 
 
Pyruvate Kina..(8)
 
 
RGS RGS4(7)
 
 
 
Tryp SPc(7)
 
 
BioAssay Types:
Screening(395)
 
 
 
 
Confirmatory(234)
 
 
 
 
 
Literature(13)
 
 
BioActivity Types:
Potency(179)
 
 
 
 
IC50(36)
 
 
 
EC50(10)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 557    Data Row: 648   Total Pages: 33   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26725387]
EC50 47.073Luminescence Cell-Based Dose Response HTS to Identify Compounds Cytotoxic to BJ-TERT RAS-Independent Fibroblast [AID1933, Type: confirmatory]
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2
[SID26725387]
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL). [AID2129, Type: screening]bcl-xL [Homo sapiens] [gi:510901]
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3
[SID26725387]
TRFRET-based biochemical primary high throughput screening assay to identify small molecules that bind to the HIV-1-gp120 binding antibody, PG9 [AID624416, Type: screening]Envelope surface glycoprotein gp160, precursor [Human immunodeficiency virus 1] [gi:9629363]
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4
[SID26725387]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of GLD-1 protein - TGE RNA interaction. [AID2280, Type: screening]Protein GLD-1 [Caenorhabditis elegans] [gi:17507875]
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5
[SID26725387]
Primary cell-based high-throughput screening assay for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4) [AID463165, Type: screening]regulator of G-protein signaling 4 isoform 2 [Homo sapiens] [gi:5032039]
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6
[SID26725387]
Validation assay for identification of compounds that inhibit the regulator of G-protein signaling 4 (RGS4) [AID492999, Type: screening]regulator of G-protein signaling 4 isoform 2 [Homo sapiens] [gi:5032039]
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7
[SID26725387]
Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput primary assay to identify inhibitors of Protein Phosphatase 1 (PP1). [AID2235, Type: screening]serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform 3 [Homo sapiens] [gi:56790945]
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8
[SID26725387]
TR-FRET-based primary biochemical high throughput screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3). [AID2300, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
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9
[SID26725387]
TR-FRET-based primary biochemical high-throughput screening assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization [AID1899, Type: screening]core protein, partial [Hepatitis C virus] [gi:83779224]
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10
[SID26725387]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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11
[SID26725387]
Potency 0.0037Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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12
[SID26756333]
Potency 6.3096qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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13
[SID26725387]
Potency 7.9433qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding [AID2675, Type: confirmatory]muscleblind-like protein 1 isoform a [Homo sapiens] [gi:41281591]
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14
[SID26725387]
Potency 7.9433qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
View
15
[SID26725387]
EC50 150Luminescence Cell-Based Dose Response HTS to Identify Compounds Cytotoxic to DRD Non-Viral Oncogenic Fibroblast [AID1934, Type: confirmatory]
View
16
[SID26725387]
EC50 150Luminescence Cell-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to BJeLR RAS-Dependent Fibroblast [AID1936, Type: confirmatory]
View
17
[SID26725387]
Conc @ Max Fold Increase A high-throughput screen to identify small molecule compounds that augment HSV replication [AID1956, Type: confirmatory]
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18
[SID26725387]
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity [AID2099, Type: screening]
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19
[SID26725387]
Fluorescence Cell-Free Homogeneous Primary HTS to Identify Inhibitors of the RanGTP-Importin-beta complex [AID2216, Type: screening]
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20
[SID26725387]
Potency qHTS Assay for Modulators of miRNAs and/orActivators of miR-21 [AID2288, Type: confirmatory]
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