TG101348 (CID 16722836) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(327)
 
 
Inactive(8)
 
 
Unspecified(119)
 
 
Top Targets:
PKc(55)
 
 
 
PKc like(34)
 
 
 
STKc AGC(24)
 
 
 
PTKc Abl(16)
 
 
PTKc EGFR(12)
 
 
 
BioAssay Types:
Literature(446)
 
 
 
Confirmatory(8)
 
 
BioActivity Types:
Kd(442)
 
 
 
Potency(8)
 
 
IC50(4)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 454    Data Row: 454   Total Pages: 10   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123089189]
Kd 0.0011Binding constant for GAK kinase domain [AID625012, Type: Literature]Cyclin-G-associated kinas [gi:17375734]
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2
[SID123089189]
Kd 0.0011Binding constant for GAK kinase domain [AID625012, Type: Literature]Cyclin-G-associated kinas [gi:17375734]
View
3
[SID123089189]
Kd 0.0011Binding constant for JAK2(JH1domain-catalytic) kinase domain [AID624973, Type: Literature]Tyrosine-protein kinase JAK2 [gi:12643404]
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4
[SID123089189]
Kd 0.0011Binding constant for JAK2(JH1domain-catalytic) kinase domain [AID624973, Type: Literature]Tyrosine-protein kinase JAK2 [gi:12643404]
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5
[SID123089189]
Kd 0.0011Binding constant for JAK2(JH1domain-catalytic) kinase domain [AID624973, Type: Literature]Tyrosine-protein kinase JAK2 [gi:12643404]
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6
[SID123089189]
Kd 0.0012Binding constant for DAPK3 kinase domain [AID624834, Type: Literature]Death-associated protein kinase 3 [gi:38604691]
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7
[SID123089189]
Kd 0.0012Binding constant for DAPK3 kinase domain [AID624834, Type: Literature]Death-associated protein kinase 3 [gi:38604691]
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8
[SID123089189]
IC50 0.003Inhibition of human recombinant JAK2 by TR-FRET assay [AID538224, Type: Literature]Tyrosine-protein kinase JAK2 [gi:12643404]
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9
[SID123089189]
IC50 0.003Inhibition of human recombinant JAK2 by TR-FRET assay [AID538224, Type: Literature]Tyrosine-protein kinase JAK2 [gi:12643404]
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10
[SID123089189]
IC50 0.003Inhibition of human recombinant JAK2 by TR-FRET assay [AID538224, Type: Literature]Tyrosine-protein kinase JAK2 [gi:12643404]
View
11
[SID123089189]
Kd 0.0049Binding constant for FLT3(D835H) kinase domain [AID624935, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
12
[SID123089189]
Kd 0.0049Binding constant for FLT3(D835H) kinase domain [AID624935, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
13
[SID123089189]
Kd 0.0049Binding constant for FLT3(D835H) kinase domain [AID624935, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
14
[SID123089189]
Kd 0.0064Binding constant for FLT3(D835Y) kinase domain [AID624936, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
15
[SID123089189]
Kd 0.0064Binding constant for FLT3(D835Y) kinase domain [AID624936, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
16
[SID123089189]
Kd 0.0064Binding constant for FLT3(D835Y) kinase domain [AID624936, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
17
[SID123089189]
Kd 0.0066Binding constant for STK16 kinase domain [AID624775, Type: Literature]Serine/threonine-protein kinase 16 [gi:46577677]
View
18
[SID123089189]
Kd 0.0066Binding constant for STK16 kinase domain [AID624775, Type: Literature]Serine/threonine-protein kinase 16 [gi:46577677]
View
19
[SID123089189]
Kd 0.0066Binding constant for STK16 kinase domain [AID624775, Type: Literature]Serine/threonine-protein kinase 16 [gi:46577677]
View
20
[SID123089189]
Kd 0.013Binding constant for DCAMKL3 kinase domain [AID624707, Type: Literature]Serine/threonine-protein kinase DCLK3 [gi:115502142]
View
21
[SID123089189]
Kd 0.013Binding constant for DCAMKL3 kinase domain [AID624707, Type: Literature]Serine/threonine-protein kinase DCLK3 [gi:115502142]
View
22
[SID123089189]
Kd 0.013Binding constant for FLT3(K663Q) kinase domain [AID624938, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
23
[SID123089189]
Kd 0.013Binding constant for FLT3(K663Q) kinase domain [AID624938, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
24
[SID123089189]
Kd 0.013Binding constant for FLT3(K663Q) kinase domain [AID624938, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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25
[SID123089189]
Kd 0.013Binding constant for FLT3 kinase domain [AID624934, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
26
[SID123089189]
Kd 0.013Binding constant for FLT3 kinase domain [AID624934, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
27
[SID123089189]
Kd 0.013Binding constant for FLT3 kinase domain [AID624934, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
28
[SID123089189]
Kd 0.016Binding constant for FLT3(ITD) kinase domain [AID624937, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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29
[SID123089189]
Kd 0.016Binding constant for FLT3(ITD) kinase domain [AID624937, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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30
[SID123089189]
Kd 0.016Binding constant for FLT3(ITD) kinase domain [AID624937, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
31
[SID123089189]
Kd 0.016Binding constant for DAPK1 kinase domain [AID624971, Type: Literature]Death-associated protein kinase 1 [gi:317373595]
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32
[SID123089189]
Kd 0.016Binding constant for DAPK1 kinase domain [AID624971, Type: Literature]Death-associated protein kinase 1 [gi:317373595]
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33
[SID123089189]
Kd 0.018Binding constant for JAK1(JH1domain-catalytic) kinase domain [AID624859, Type: Literature]Tyrosine-protein kinase JAK1 [gi:215274013]
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34
[SID123089189]
Kd 0.018Binding constant for JAK1(JH1domain-catalytic) kinase domain [AID624859, Type: Literature]Tyrosine-protein kinase JAK1 [gi:215274013]
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35
[SID123089189]
Kd 0.019Binding constant for YSK4 kinase domain [AID625136, Type: Literature]Mitogen-activated protein kinase kinase kinase 19 [gi:74755104]
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36
[SID123089189]
Kd 0.02Binding constant for FLT3(N841I) kinase domain [AID624939, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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37
[SID123089189]
Kd 0.02Binding constant for FLT3(N841I) kinase domain [AID624939, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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38
[SID123089189]
Kd 0.02Binding constant for FLT3(N841I) kinase domain [AID624939, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
39
[SID123089189]
Kd 0.021Binding constant for TYK2(JH1domain-catalytic) kinase domain [AID624912, Type: Literature]Non-receptor tyrosine-protein kinase TYK [gi:56405328]
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40
[SID123089189]
Kd 0.021Binding constant for TYK2(JH1domain-catalytic) kinase domain [AID624912, Type: Literature]Non-receptor tyrosine-protein kinase TYK [gi:56405328]
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41
[SID123089189]
Kd 0.021Binding constant for TYK2(JH1domain-catalytic) kinase domain [AID624912, Type: Literature]Non-receptor tyrosine-protein kinase TYK [gi:56405328]
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42
[SID123089189]
Kd 0.029Binding constant for FLT3(R834Q) kinase domain [AID624940, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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43
[SID123089189]
Kd 0.029Binding constant for FLT3(R834Q) kinase domain [AID624940, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
44
[SID123089189]
Kd 0.029Binding constant for FLT3(R834Q) kinase domain [AID624940, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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45
[SID123089189]
Kd 0.029Binding constant for DAPK2 kinase domain [AID625077, Type: Literature]Death-associated protein kinase 2 [gi:38605084]
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46
[SID123089189]
Kd 0.029Binding constant for DAPK2 kinase domain [AID625077, Type: Literature]Death-associated protein kinase 2 [gi:38605084]
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47
[SID123089189]
Kd 0.032Binding constant for BIKE kinase domain [AID625109, Type: Literature]BMP-2-inducible protein kinase [gi:34222653]
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48
[SID123089189]
Kd 0.032Binding constant for BIKE kinase domain [AID625109, Type: Literature]BMP-2-inducible protein kinase [gi:34222653]
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49
[SID123089189]
Kd 0.034Binding constant for ARK5 kinase domain [AID625088, Type: Literature]NUAK family SNF1-like kinase 1 [gi:14424095]
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50
[SID123089189]
Kd 0.034Binding constant for ARK5 kinase domain [AID625088, Type: Literature]NUAK family SNF1-like kinase 1 [gi:14424095]
View