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BioActivity Data for Compound phentin acetate (CID 16682804)

BioActivity Outcomes:
Active(59)
 
 
Inactive(43)
 
 
Inconclusive(48)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
 
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
NR LBD VDR(5)
 
 
 
NR LBD TR(5)
 
 
 
 
BioAssay Types:
Confirmatory(106)
 
 
 
 
Summary(28)
 
 
 
 
Screening(5)
 
 
BioAssay Categories:
In vivo(2)
 
 
Biochemical(2)
 
 
Toxicity(6)
 
 
 
 
Cell-based(2)
 
 
BioActivity Types:
Potency(128)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 146    Data Row: 150   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209798]
Potency-Replicate_1 0.0243qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID1159521, Type: confirmatory]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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2
[SID144209798]
Potency-Replicate_1 0.0344qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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3
[SID144209798]
Ratio Potency (uM) 0.0374263qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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4
[SID144209798]
Potency-Replicate_1 0.077qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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5
[SID144209798]
Potency-Replicate_1 0.077qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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6
[SID144209798]
Potency-Replicate_1 0.0871qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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7
[SID144209798]
Potency-Replicate_1 0.0969qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID1159520, Type: confirmatory]
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8
[SID144209798]
Potency-Replicate_1 0.0977qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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9
[SID144209798]
Potency-Replicate_1 0.0977qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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10
[SID144209798]
Ratio Potency (uM) 0.117379qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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11
[SID144209798]
Potency-Replicate_1 0.122qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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12
[SID144209798]
Potency-Replicate_1 0.122qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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13
[SID144209798]
Potency-Replicate_1 0.138qHTS assay to identify small molecule agonists of the RXR signaling pathway - cell viability counter screen [AID1159529, Type: confirmatory]
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14
[SID144209798]
Potency-Replicate_1 0.138qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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15
[SID144209798]
Potency-Replicate_1 0.138qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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16
[SID144209798]
Potency-Replicate_1 0.1723qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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17
[SID144209798]
Potency-Replicate_1 0.1723qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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18
[SID144209798]
Potency-Replicate_1 0.1723qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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19
[SID144209798]
Potency-Replicate_1 0.1949qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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20
[SID144209798]
Potency-Replicate_1 0.2187qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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