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Menthol (CID 16666) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(696)
 
 
Inconclusive(46)
 
 
Unspecified(23)
 
 
Top Targets:
NR LBD PPAR(47)
 
 
NR LBD ER(44)
 
 
 
NR LBD AR(44)
 
 
 
NR LBD GR(26)
 
 
 
NR LBD Fxr(22)
 
 
BioAssay Types:
Confirmatory(391)
 
 
 
Screening(145)
 
 
 
Summary(135)
 
 
 
Literature(30)
 
 
 
 
BioActivity Types:
Potency(494)
 
 
 
EC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 345    Data Row: 771   Total Pages: 39   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103582089]
EC50 23.4Agonist activity at TRPM8 in differentiated rat/mouse F11 cells assessed as increase in intracellular Ca2+ level measured after 20 seconds by Fura-2-AM based fluorescence assay [AID776517, Type: Literature]
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2
[SID99494953]
HTS for Bacterial rRNA inhibitors Measured in Microorganism-Based System Using Plate Reader - 7056-01_Inhibitor_SinglePoint_HTS_Activity [AID720706, Type: screening]
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3
[SID103582089]
Potentiation of acetone-induced cold allodynic response in Swiss CD-1 mouse chronic constriction injury model applied topically 20 mins prior to acetone-challenge measured for 7 to 9 mins post acetone-challenge [AID776502, Type: Literature]
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4
[SID103582089]
Agonist activity at TRPM8 in differentiated rat/mouse F11 cells assessed as increase in intracellular Ca2+ level at 1 to 300 uM measured after 1 to 15 seconds by Fura-2-AM based fluorescence assay [AID776516, Type: Literature]
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5
[SID8149920]
Screen for compounds that decrease glutamate induced motor neuron death measured by TUNEL staining for DNA degradation (MNGlu) [AID1594, Type: other]
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6
[SID48415372]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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7
[SID103582089]
EC50 100GRAC: human TRPA1 activator [AID540550, Type: Literature]Transient receptor potential cation channel subfamily A member 1 [gi:313104269]
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8
[SID103582089]
Specific activity of expressed human recombinant UGT2B15 [AID624616, Type: Literature]UDP-glucuronosyltransferase 2B15 [gi:332278237]
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9
[SID103582089]
Inhibition of COX2 at 100 uM by scintillation proximity assay [AID336478, Type: Literature]
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10
[SID103582089]
Inhibition of COX2 at 0.1 ug/mL [AID403629, Type: Literature]
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11
[SID103582089]
Specific activity of expressed human recombinant UGT1A9 [AID624612, Type: Literature]UDP-glucuronosyltransferase 1-9 [gi:29839451]
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12
[SID103582089]
Specific activity of expressed human recombinant UGT1A8 [AID624611, Type: Literature]UDP-glucuronosyltransferase 1-8 [gi:29839637]
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13
[SID103582089]
Specific activity of expressed human recombinant UGT1A6 [AID624609, Type: Literature]UDP-glucuronosyltransferase 1-6 [gi:29840832]
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14
[SID8149920]
Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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15
[SID8149920]
Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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16
[SID8149920]
Screening of compounds showing protective effect against cell death induced by familial amyotrophic lateral sclerosis (FALS)-linked mutantsuperoxide dismutase 1 (SOD1) (ALSOD1) [AID1605, Type: other]
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17
[SID8149920]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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18
[SID8149920]
Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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19
[SID8149920]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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20
[SID8149920]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubH) [AID1616, Type: other]
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