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BioActivity Data for Compound Menthol (CID 16666)

BioActivity Outcomes:
Active(7)
 
 
Inactive(751)
 
 
Inconclusive(46)
 
 
Unspecified(28)
 
 
Top Targets:
NR LBD PPAR(47)
 
 
NR LBD ER(44)
 
 
 
NR LBD AR(44)
 
 
 
NR LBD GR(26)
 
 
 
NR LBD TR(22)
 
 
 
BioAssay Types:
Confirmatory(431)
 
 
 
Summary(150)
 
 
 
Screening(145)
 
 
 
Literature(32)
 
 
 
 
BioAssay Categories:
In vitro(10)
 
 
 
In vivo(2)
 
 
Biochemical(54)
 
 
 
 
Toxicity(58)
 
 
 
 
 
ADME(9)
 
 
Cell-based(67)
 
 
 
 
 
Organism-base..(7)
 
 
 
 
BioActivity Types:
Potency(549)
 
 
 
EC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 362    Data Row: 832   Total Pages: 42   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103582089]
EC50 23.4Agonist activity at TRPM8 in differentiated rat/mouse F11 cells assessed as increase in intracellular Ca2+ level measured after 20 seconds by Fura-2-AM based fluorescence assay [AID776517, Type: Literature]
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2
[SID103582089]
Agonist activity at TRPM8 in differentiated rat/mouse F11 cells assessed as increase in intracellular Ca2+ level at 1 to 300 uM measured after 1 to 15 seconds by Fura-2-AM based fluorescence assay [AID776516, Type: Literature]
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3
[SID103582089]
Potentiation of acetone-induced cold allodynic response in Swiss CD-1 mouse chronic constriction injury model applied topically 20 mins prior to acetone-challenge measured for 7 to 9 mins post acetone-challenge [AID776502, Type: Literature]
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4
[SID103582089]
Contact insecticidal activity against cotton leafworm Spodoptera littoralis third-instar larvae exposed to 1 mg/larva compound application through dorsum of larvae followed by feeding on fresh castor bean leaves assessed as insect mortality after 24 hr [AID1108166, Type: other]
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5
[SID8149920]
Screen for compounds that decrease glutamate induced motor neuron death measured by TUNEL staining for DNA degradation (MNGlu) [AID1594, Type: other]
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6
[SID48415372]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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7
[SID99494953]
HTS for Bacterial rRNA inhibitors Measured in Microorganism-Based System Using Plate Reader - 7056-01_Inhibitor_SinglePoint_HTS_Activity [AID720706, Type: screening]
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8
[SID103582089]
EC50 100GRAC: human TRPA1 activator [AID540550, Type: Literature]Transient receptor potential cation channel subfamily A member 1 [gi:313104269]
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9
[SID103582089]
Specific activity of expressed human recombinant UGT2B15 [AID624616, Type: Literature]UDP-glucuronosyltransferase 2B15 [gi:332278237]
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10
[SID103582089]
Specific activity of expressed human recombinant UGT2A1 [AID624614, Type: Literature]UDP-glucuronosyltransferase 2A1 [gi:296452854]
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11
[SID26757664]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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12
[SID8149920]
Assay to identify inhibitors of polyglutamine-induced caspase-3 activation (CASP3) [AID1583, Type: other]
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13
[SID8149920]
Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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14
[SID8149920]
Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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15
[SID8149920]
Screening of compounds showing protective effect against cell death induced by familial amyotrophic lateral sclerosis (FALS)-linked mutantsuperoxide dismutase 1 (SOD1) (ALSOD1) [AID1605, Type: other]
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16
[SID8149920]
Screen for compounds that correct neuronal dysfunction without cell death as induced by the expression of polyglutamine-expanded, N-terminal huntingtin in C. elegans mechanosensory neurons (HDELENEU) [AID1599, Type: other]
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17
[SID103582089]
Contact molluscicidal activity against Theba pisana (white garden snail ) exposed to compound throgh application to surface of snail body inside shell assessed as compound level per snail causing snail mortality after 24 hr [AID1108169, Type: other]
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18
[SID103582089]
EC50 Fungitoxicity against Colletotrichum gloeosporioides assessed as mycelial growth inhibition by poisoned food technique [AID1102450, Type: Literature]
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19
[SID8149920]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubU) [AID1593, Type: other]
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20
[SID103582089]
Specific activity of expressed human recombinant UGT2B7 [AID624619, Type: Literature]UDP-glucuronosyltransferase 2B7 [gi:136727]
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