pyrrolidino-benzylphenoxyethanamine (CID 164472) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(6)
 
 
Unspecified(3)
 
 
BioAssay Types:
Literature(9)
 
 
 
BioActivity Types:
IC50(6)
 
 
SAR
Target summary
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 9    Data Row: 9   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103177330]
IC50 0.026In vitro inhibition of recombinant human leukotriene A4 hydrolase. [AID99748, Type: Literature]
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2
[SID103177330]
IC50 0.026Inhibition of leukotriene A4 hydrolase in human recombinant assay [AID99749, Type: Literature]
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3
[SID103177330]
IC50 0.026Inhibitory activity was determined against Leukotriene A4 hydrolase [AID99747, Type: Literature]
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4
[SID103177330]
IC50 0.12Inhibition of leukotriene B4 production in human whole blood [AID92878, Type: Literature]
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5
[SID103177330]
IC50 0.12Inhibition of LTB4 production from whole human blood. [AID92873, Type: Literature]
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6
[SID103177330]
IC50 0.12Inhibitory activity was determined for LTB4 production in human whole blood. [AID223081, Type: Literature]
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7
[SID103177330]
 Ex vivo inhibition of LTB4 production in mouse whole blood following 10 mg/kg p.o. administration. [AID116343, Type: Literature]
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8
[SID103177330]
 Ex vivo inhibition of LTB4 production in mouse whole blood at 10 mg/kg [AID138548, Type: Literature]
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9
[SID103177330]
 Percent inhibition was determined at a dose of 10 mg/Kg in mouse ex vivo assay [AID138599, Type: Literature]
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