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Pimozide (CID 16362) - Compound BioActivity Data
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BioActivity Outcomes:
Active(221)
 
 
Inactive(1421)
 
 
Inconclusive(282)
 
 
Unspecified(117)
 
 
Top Targets:
7TM GPCR Srx(38)
 
 
 
 
p450(35)
 
 
 
 
 
7TM GPCR Srsx(30)
 
 
 
 
NR LBD PPAR(27)
 
 
 
 
NR LBD TR(24)
 
 
 
 
BioAssay Types:
Confirmatory(973)
 
 
 
 
 
Screening(641)
 
 
 
 
Literature(242)
 
 
 
 
 
Summary(49)
 
 
 
 
BioActivity Types:
Potency(778)
 
 
 
 
 
IC50(88)
 
 
 
 
 
EC50(13)
 
 
 
Ki(7)
 
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1360    Data Row: 2041   Total Pages: 103   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103503415]
IC50 0.0004Inhibition of [3H]haloperidol binding to dopamine receptors in rat striatal membranes. [AID62722, Type: Literature]
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2
[SID103503415]
Ki 0.0005Binding affinity towards rat 5-hydroxytryptamine 7 receptor [AID6648, Type: Literature]
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3
[SID103503415]
Ki 0.0006Binding affinity of compound towards Dopamine receptor D2 using [3H]raclopride (1.2 nM) ligand in striatum bovine was determined [AID62330, Type: Literature]
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4
[SID103503415]
IC50 0.00302Inhibition of human ERG channel in HEK293 cells by voltage-clamp method [AID392051, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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5
[SID103503415]
Ki 0.012Binding affinity towards Dopamine receptor D2 [AID64143, Type: Literature]
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6
[SID103503415]
IC50 0.018K+ channel blocking activity in human embryonic kidney cells expressing HERG Kv11.1 [AID82355, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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7
[SID103503415]
IC50 0.018Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1 [AID161283, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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8
[SID103503415]
IC50 0.018Inhibitory activity against Potassium channel HERG [AID161284, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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9
[SID103503415]
IC50 0.0182Inhibition of human ERG in MCF7 cells [AID420668, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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10
[SID103503415]
Kd 0.029Inhibition of dopamine D2 receptor [AID499463, Type: Literature]
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11
[SID103503415]
Kd 0.04Inhibition of T-type alpha1G calcium channel [AID549672, Type: Literature]
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12
[SID103503415]
Ki 0.042Displacement of [3H]Astemizole from hERG expressed in HEK293 cells at 10 uM [AID274128, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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13
[SID103503415]
IC50 0.05012Inhibition of human Potassium channel HERG expressed in mammalian cells [AID161281, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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14
[SID103503415]
IC50 0.05012Inhibition of human ERG expressed in CHO cells by whole cell patch clamp technique [AID408340, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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15
[SID103503415]
IC50 0.05012Inhibitory concentration against potassium channel HERG [AID243151, Type: Literature]
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16
[SID103503415]
IC50 0.0546Inhibition of human ERG channel [AID397743, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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17
[SID103503415]
IC50 0.05495Inhibition of human ERG [AID576612, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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18
[SID50104653]
Potency 0.0562qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
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19
[SID50104653]
Potency 0.0562qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
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20
[SID103503415]
Ki 0.071Binding affinity towards human 5-hydroxytryptamine 6 receptor [AID6563, Type: Literature]
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