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MLS001233727 (CID 16330874) - Compound BioActivity Data
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BioActivity Outcomes:
Active(106)
 
 
Inactive(507)
 
 
Inconclusive(19)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
7TM GPCR Srsx(15)
 
 
alkPPc(10)
 
 
 
DSPc(9)
 
 
 
TRP 2(9)
 
 
 
BioAssay Types:
Screening(396)
 
 
 
 
Confirmatory(215)
 
 
 
 
 
Literature(14)
 
 
 
BioActivity Types:
Potency(135)
 
 
 
 
 
IC50(55)
 
 
 
 
EC50(13)
 
 
 
 
AC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 577    Data Row: 633   Total Pages: 32   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85176685]
IC50_Mean 0.05Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP [AID1077, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
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2
[SID85176685]
IC50_Mean 0.065SAR VHR1 Fluorescent Assay for In Vitro dose response studies [AID1957, Type: confirmatory]dual specificity protein phosphatase 3 [Homo sapiens] [gi:4758208]
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3
[SID85176685]
IC50_Mean 0.066MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds [AID2068, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
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4
[SID85176685]
IC50_Mean 0.0828SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 2 [AID2684, Type: confirmatory]dual specificity protein phosphatase 3 [Homo sapiens] [gi:4758208]
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5
[SID49680398]
Potency 0.1192qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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6
[SID85176685]
IC50_Mean 0.121SAR VHR1 absorbance Assay for In Vitro dose response studies. [AID1958, Type: confirmatory]dual specificity protein phosphatase 3 [Homo sapiens] [gi:4758208]
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7
[SID49680398]
Potency 0.1457qHTS for inhibitors of Phosphogylcerate Kinase: Hit Validation Screen [AID686980, Type: confirmatory]phosphoglycerate kinase [Trypanosoma brucei] [gi:115503961]
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8
[SID49680398]
Potency 0.2668qHTS for Inhibitors of Polymerase Kappa: Confirmatory Assay for Cherry-picked Compounds [AID720501, Type: Literature]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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9
[SID49680398]
Potency 0.271qHTS for Inhibitors of WRN Helicase: BLM Helicase Counterscreen for WRN Inhibitors [AID720503, Type: confirmatory]Bloom syndrome protein isoform 1 [Homo sapiens] [gi:4557365]
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10
[SID49680398]
Potency 0.3162qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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11
[SID49680398]
Potency 0.5406qHTS for Inhibitors of WRN Helicase: Confirmatory Assay for Cherry-picked Compounds. [AID720497, Type: confirmatory]WRN [Homo sapiens] [gi:3719421]
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12
[SID49680398]
Potency 0.5973qHTS for Inhibitors of Polymerase Iota: Confirmatory Assay for Cherry-picked Compounds [AID720496, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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13
[SID49680398]
Potency 0.6012qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds [AID720502, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
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14
[SID49680398]
IC50 0.763Dose response confirmation of uHTS RPN11 inhibitor hits in a Fluorescence Polarization assay [AID602368, Type: confirmatory]PSMD14 protein [Homo sapiens] [gi:16306916]
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15
[SID49680398]
Potency 0.7943qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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16
[SID49680398]
Potency 0.7943qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
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17
[SID49680398]
Potency 0.8437qHTS for Inhibitors of WRN Helicase [AID651768, Type: confirmatory]WRN [Homo sapiens] [gi:3719421]
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18
[SID49680398]
Potency 0.8913qHTS for Inhibitors of PI5P4K: Confirmation in Primary Assay [AID743286, Type: confirmatory]Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [gi:18266879]
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19
[SID49680398]
Potency 1qHTS Assay to Find Inhibitors of Phosphoglycerate Kinase [AID602233, Type: confirmatory]phosphoglycerate kinase [Trypanosoma brucei] [gi:115503961]
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20
[SID49680398]
Potency 1.2589qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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