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isovitexin (CID 162350) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Inactive(408)
 
 
Inconclusive(2)
 
 
Unspecified(17)
 
 
Top Targets:
7TM GPCR Srx(14)
 
 
7TM GPCR Srsx(12)
 
 
Peptidase C48(5)
 
 
 
RasGEF(4)
 
 
ABCC CFTR1(4)
 
 
BioAssay Types:
Screening(273)
 
 
 
Confirmatory(121)
 
 
 
 
Literature(30)
 
 
 
BioActivity Types:
Potency(112)
 
 
 
 
IC50(16)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 379    Data Row: 428   Total Pages: 22   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85148333]
uHTS Fluorescent Assay Using Nedd8 Protein Substrate for Identification of Inhibitors of Sentrin-Specific Protease 8 (SENP8) [AID602440, Type: screening]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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2
[SID103598746]
IC50 50Cytotoxicity against human HF19 cells assessed as cell viability after 24 hrs by MTT assay [AID721014, Type: Literature]
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3
[SID103598746]
IC50 50Cytotoxicity against human NB1RGB cells assessed as cell viability after 24 hrs by MTT assay [AID721015, Type: Literature]
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4
[SID103598746]
IC50 50Cytotoxicity against human HepG2 cells assessed as cell viability after 24 hrs by MTT assay [AID721016, Type: Literature]
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5
[SID103598746]
IC50 50Cytotoxicity against human HCT15 cells assessed as cell viability after 24 hrs by MTT assay [AID721017, Type: Literature]
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6
[SID103598746]
IC50 50Cytotoxicity against human KATO III cells assessed as cell viability after 24 hrs by MTT assay [AID721018, Type: Literature]
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7
[SID103598746]
IC50 50Cytotoxicity against human Jurkat cells assessed as cell viability after 24 hrs by MTT assay [AID721019, Type: Literature]
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8
[SID103598746]
IC50 50Cytotoxicity against human THP1 cells assessed as cell viability after 24 hrs by MTT assay [AID721020, Type: Literature]
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9
[SID103598746]
IC50 50Cytotoxicity against human U937 cells assessed as cell viability after 24 hrs by MTT assay [AID721021, Type: Literature]
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10
[SID103598746]
IC50 50Cytotoxicity against human HL60 cells assessed as cell viability after 24 hrs by MTT assay [AID721022, Type: Literature]
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11
[SID103598746]
Antioxidant activity assessed as trolox equivalent by TEAC assay [AID456317, Type: Literature]
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12
[SID103598746]
Inhibition of thrombin-induced platelet aggregation in rabbit plasma at 300 uM preincubated 3 mins before addition of thrombin by turbidimetric method [AID403582, Type: Literature]
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13
[SID103598746]
Inhibition of arachidonic acid-induced platelet aggregation in rabbit plasma at 300 uM preincubated 3 mins before addition of thrombin by turbidimetric method [AID403584, Type: Literature]
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14
[SID103598746]
Inhibition of collagen-induced platelet aggregation in rabbit plasma at 300 uM preincubated 3 mins before addition of thrombin by turbidimetric method [AID403591, Type: Literature]
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15
[SID103598746]
Inhibition of platelet activating factor-induced platelet aggregation in rabbit plasma at 300 uM preincubated 3 mins before addition of thrombin by turbidimetric method [AID403594, Type: Literature]
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16
[SID85148333]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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17
[SID103598746]
Inhibition of horse BChE at 2 mg/ml by Ellman's method [AID697853, Type: Literature]Cholinesterase [gi:21362409]
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18
[SID103598746]
Inhibition of electric eel AChE at 2 mg/ml by Ellman's method [AID697852, Type: Literature]Acetylcholinesterase [gi:14916521]
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19
[SID85148333]
Potency 1qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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20
[SID85148333]
Potency 4.4668qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624287, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
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