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MLS000419194 (CID 16195022) - Compound BioActivity Data
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BioActivity Outcomes:
Active(111)
 
 
Inactive(502)
 
 
Inconclusive(43)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(39)
 
 
 
Bcl-2 like(11)
 
 
 
alkPPc(10)
 
 
G-alpha(8)
 
 
 
ANK(7)
 
 
 
 
BioAssay Types:
Screening(408)
 
 
 
 
Confirmatory(226)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(156)
 
 
 
 
 
IC50(40)
 
 
 
 
EC50(14)
 
 
 
 
AC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 590    Data Row: 657   Total Pages: 33   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24816850]
CC50 9.92e-06Cytotoxicity counterscreen assay for transcriptional activators of heat shock protein 70 (Hsp70) [AID1259, Type: confirmatory]
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2
[SID24816850]
Potency 0.3162Confirmation screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504848, Type: confirmatory]
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3
[SID24816850]
EC50 1.132Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR) [AID463088, Type: confirmatory]aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003]
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4
[SID24816850]
AC50_uM 1.767Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis [AID449756, Type: confirmatory]
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5
[SID24816850]
EC50 2.209Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter [AID588504, Type: confirmatory] [geneid:2395]
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6
[SID24816850]
Potency 2.3109qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID24816850]
Potency 2.5119qHTS FP-Based Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2573, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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8
[SID24816850]
Potency 2.5929qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID24816850]
Potency 2.9362Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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10
[SID24816850]
CC50 2.941A Cell Based Secondary Assay To Explore Cytotoxicity of Compounds that Inhibit Mycobacterium Tuberculosis [AID435019, Type: confirmatory]
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11
[SID24816850]
CC50 3.05A Cell Based Secondary Assay to Explore Cytotoxicity in Vero E6 Cells of Compounds that Modulate Non-Replicating, Drug-tolerant Mycobacterium tuberculosis [AID492998, Type: confirmatory]
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12
[SID24816850]
AC50_uM 3.1Luminescence Cell-Based Counter Screen to Identify Inhibitors of Cytokine Induced Apoptosis [AID463206, Type: confirmatory]
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13
[SID24816850]
Potency 3.2643qHTS for inhibitors of Vif-A3F interactions: Cherry picks counterscreen [AID651815, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3F isoform a [Homo sapiens] [gi:22907044]
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14
[SID24816850]
Potency 3.5481qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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15
[SID24816850]
Potency 3.5481qHTS for Small Molecule Inhibitors of the ERG Ets/DNA interaction: HTRF assay against cherry picks [AID651804, Type: confirmatory]transcriptional regulator ERG isoform 3 [Homo sapiens] [gi:343478176]
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16
[SID24816850]
Potency 3.5481Confirmation qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2572, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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17
[SID24816850]
CC50 3.778A Cell Based Secondary Assay to Explore Cytotoxicity in THP-1 Cells of Compounds that Modulate Non-Replicating, Drug-tolerant Mycobacterium tuberculosis [AID489025, Type: confirmatory]
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18
[SID24816850]
Potency 3.9811Quantitative High-Throughput Screen for Regulators of Epigenetic Control [AID1865, Type: confirmatory]
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19
[SID24816850]
Potency 4.4668Confirmation screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504850, Type: confirmatory]
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20
[SID24816850]
AC50_uM 4.53Shn3: Cytotox assay Measured in Cell-Based System Using Plate Reader - 2134-03_Inhibitor_Dose_CherryPick_Activity [AID624134, Type: confirmatory]
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