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Ambcb30248503 (CID 16192040) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Inactive(663)
 
 
Inconclusive(8)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(22)
 
 
7TM GPCR Srsx(17)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(456)
 
 
 
 
Confirmatory(193)
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(145)
 
 
 
 
IC50(35)
 
 
EC50(7)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 611    Data Row: 673   Total Pages: 34   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24800371]
Counterscreen for inhibitors of 5-meCpG-binding domain protein 2 (MBD2): TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of binding of ubiquitin-like with PHD and ring finger domains 1 (UHRF1) to methylated oligonucleotide [AID687016, Type: screening]E3 ubiquitin-protein ligase UHRF1 isoform 1 [Homo sapiens] [gi:115430235]
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2
[SID24800371]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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3
[SID24800371]
Potency 1.9953qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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4
[SID24800371]
Potency 10qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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5
[SID24800371]
Potency 89.1251qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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6
[SID24800371]
uHTS Fluorescent assay for identification of inhibitors of Apaf-1 [AID489030, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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7
[SID24800371]
uHTS Fluorescent assay for identification of activators of Apaf-1 [AID489031, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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8
[SID24800371]
Potency VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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9
[SID24800371]
Potency qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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10
[SID24800371]
Screen for Chemicals that Inhibit the RAM Network [AID868, Type: screening]
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11
[SID24800371]
NIH Compound Library Profiling: Compound and DTT Dependent Redox Cycling H2O2 Generation. [AID878, Type: screening]
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12
[SID24800371]
Counter Screen for Luciferase-based Primary Inhibition Assays [AID1006, Type: screening]
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13
[SID24800371]
Counter Screen for Luciferase-based Primary Stimulation Assays [AID1027, Type: screening]
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14
[SID24800371]
Leishmania major promastigote HTS [AID1063, Type: screening]
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15
[SID24800371]
EC50 High Throughput Screen for Inhibitors of ER Stress-induced Cell Death in a 384 well format. [AID1222, Type: confirmatory]
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16
[SID24800371]
Anti-Viral Drugs Against Arbovirus Infections, a Primary Screen [AID1251, Type: screening]
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17
[SID24800371]
Chemical Genetic Screen to Identify Inhibitors of Mitochondrial Fusion - Primary Screen [AID1362, Type: screening]
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18
[SID24800371]
HTS to identify inhibitors of zVAD Induced Cell Death in L929 Cells. [AID1377, Type: screening]
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19
[SID24800371]
HCS to Identify Inhibitors of Dynein Mediated Cargo Transport on Microtubules. [AID1381, Type: screening]
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20
[SID24800371]
Potency Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1463, Type: confirmatory]
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