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CHEMBL1914587 (CID 16103465) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Inactive(1)
 
 
Unspecified(3)
 
 
BioAssay Types:
Literature(8)
 
 
 
 
BioActivity Types:
EC50(2)
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 8   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136931856]
EC50 6Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay [AID630439, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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2
[SID136931856]
IC50 6.07Agonist activity at GPR35 in human HT-29 cells assessed as desensitization of 1 uM zaprinast-induced DMR after 1 hr by dynamic mass redistribution assay [AID630382, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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3
[SID136931856]
Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay in presence of GPR35 antagonist SPB05142 [AID630441, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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4
[SID136931856]
Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay in presence of 64 uM GPR35 antagonist SPB05142 [AID630442, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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5
[SID136931856]
EC50 50Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcriptional activation after 5 hrs by tango beta-arrestin translocation reporter assay [AID630386, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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6
[SID136931856]
Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcriptional activation after 5 hrs by tango beta-arrestin translocation reporter assay relative to zaprinast [AID630387, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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7
[SID136931856]
Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay relative to zaprinast [AID630381, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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8
[SID136931856]
Induction of dynamic mass redistribution in human HT-29 cells transfected with receptor-targeting iRNA-based shRNA for GPR35 knock out at 10 uM [AID630385, Type: Literature]
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