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GSK248233A (CID 16099859) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(10)
 
 
Inconclusive(1)
 
 
Unspecified(465)
 
 
Top Targets:
PKc(42)
 
 
PKc like(42)
 
 
PTKc Abl(16)
 
 
STKc AGC(16)
 
 
PTKc Src like(11)
 
 
 
BioAssay Types:
Literature(14)
 
 
 
 
Confirmatory(5)
 
 
 
 
BioActivity Types:
Potency(7)
 
 
 
 
AC50(2)
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 479    Data Row: 479   Total Pages: 24   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103504607]
IC50 0.002Inhibition of human ROCK1 in Sf9 cells [AID275148, Type: Literature]Rho-associated protein kinase 1 [gi:47605999]
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2
[SID103504607]
IC50 0.106Relaxation of phenylephrine contracted Sprague-Dawley rat aortic rings [AID275154, Type: Literature]
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3
[SID124349910]
Potency 1.0312qHTS Assay for Inhibitors of Firefly Luciferase from the GSK Published Protein Kinase Inhibitor Set [AID652016, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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4
[SID103504607]
AC50 1.0312GSK_PKIS: Inhibition of Firefly Luciferase (Data from PubChem: AID 652016) [NIH NCATS] [AID720835, Type: Literature]Luciferin 4-monooxygenase [gi:126501]
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5
[SID103504607]
AC50 GSK_PKIS: Inhibition of Sea Pansy Luciferase (Data from PubChem: AID 652015) [NIH NCATS] [AID720834, Type: Literature]Renilla-luciferin 2-monooxygenase [gi:126502]
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6
[SID103504607]
GSK_PKIS: PDGFRB mean inhibition at 0.1 uM [Nanosyn] [AID651298, Type: other]Platelet-derived growth factor receptor beta [gi:129890]
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7
[SID103504607]
GSK_PKIS: PDGFRB mean inhibition at 1 uM [Nanosyn] [AID651299, Type: other]Platelet-derived growth factor receptor beta [gi:129890]
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8
[SID103504607]
GSK_PKIS: PDGFRA mean inhibition at 0.1 uM [Nanosyn] [AID651290, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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9
[SID103504607]
GSK_PKIS: PDGFRA mean inhibition at 1 uM [Nanosyn] [AID651291, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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10
[SID103504607]
GSK_PKIS: PDGFRA (D842V mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651292, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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11
[SID103504607]
GSK_PKIS: PDGFRA (D842V mutant) mean inhibition at 1 uM [Nanosyn] [AID651293, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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12
[SID103504607]
GSK_PKIS: PDGFRA (T674I mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651294, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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13
[SID103504607]
GSK_PKIS: PDGFRA (T674I mutant) mean inhibition at 1 uM [Nanosyn] [AID651295, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
View
14
[SID103504607]
GSK_PKIS: PDGFRA (V561D mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651296, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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15
[SID103504607]
GSK_PKIS: PDGFRA (V561D mutant) mean inhibition at 1 uM [Nanosyn] [AID651297, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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16
[SID103504607]
GSK_PKIS: CDK3/cyclinE mean inhibition at 0.1 uM [Nanosyn] [AID651168, Type: other]Cyclin-dependent kinase 3 [gi:231726]
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17
[SID103504607]
GSK_PKIS: CDK3/cyclinE mean inhibition at 1 uM [Nanosyn] [AID651169, Type: other]Cyclin-dependent kinase 3 [gi:231726]
View
18
[SID103504607]
GSK_PKIS: MAPK3 mean inhibition at 0.1 uM [Nanosyn] [AID651198, Type: other]Mitogen-activated protein kinase 3 [gi:232066]
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19
[SID103504607]
GSK_PKIS: MAPK3 mean inhibition at 1 uM [Nanosyn] [AID651199, Type: other]Mitogen-activated protein kinase 3 [gi:232066]
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20
[SID103504607]
GSK_PKIS: CDK6/cyclinD3 mean inhibition at 0.1 uM [Nanosyn] [AID651174, Type: other]Cyclin-dependent kinase 6 [gi:266423]
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