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GSK248233A (CID 16099859) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(11)
 
 
Inconclusive(1)
 
 
Unspecified(465)
 
 
Top Targets:
PTKc Abl(16)
 
 
PTKc EGFR(10)
 
 
PKc like(10)
 
 
STKc MARK(8)
 
 
PTKc PDGFR al..(8)
 
 
BioAssay Types:
Literature(14)
 
 
 
 
Confirmatory(5)
 
 
 
 
BioActivity Types:
Potency(7)
 
 
 
 
AC50(2)
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 480    Data Row: 480   Total Pages: 24   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103504607]
IC50 0.002Inhibition of human ROCK1 in Sf9 cells [AID275148, Type: Literature]Rho-associated protein kinase 1 [gi:47605999]
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2
[SID103504607]
IC50 0.106Relaxation of phenylephrine contracted Sprague-Dawley rat aortic rings [AID275154, Type: Literature]
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3
[SID124349910]
Potency 1.0312qHTS Assay for Inhibitors of Firefly Luciferase from the GSK Published Protein Kinase Inhibitor Set [AID652016, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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4
[SID103504607]
AC50 1.0312GSK_PKIS: Inhibition of Firefly Luciferase (Data from PubChem: AID 652016) [NIH NCATS] [AID720835, Type: Literature]Luciferin 4-monooxygenase [gi:126501]
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5
[SID103504607]
GSK_PKIS: CK1-g2 mean inhibition at 0.1 uM [Nanosyn] [AID651158, Type: other]Casein kinase I isoform gamma-2 [gi:3024060]
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6
[SID103504607]
GSK_PKIS: CK1-g2 mean inhibition at 1 uM [Nanosyn] [AID651159, Type: other]Casein kinase I isoform gamma-2 [gi:3024060]
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7
[SID103504607]
GSK_PKIS: AKT1 mean inhibition at 0.1 uM [Nanosyn] [AID651018, Type: other]RAC-alpha serine/threonine-protein kinase [gi:60391226]
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8
[SID103504607]
GSK_PKIS: AKT1 mean inhibition at 1 uM [Nanosyn] [AID651019, Type: other]RAC-alpha serine/threonine-protein kinase [gi:60391226]
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9
[SID103504607]
GSK_PKIS: MST4 mean inhibition at 0.1 uM [Nanosyn] [AID651358, Type: other]Serine/threonine-protein kinase 26 [gi:73621232]
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10
[SID103504607]
GSK_PKIS: MST4 mean inhibition at 1 uM [Nanosyn] [AID651359, Type: other]Serine/threonine-protein kinase 26 [gi:73621232]
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11
[SID103504607]
GSK_PKIS: CK1-g1 mean inhibition at 0.1 uM [Nanosyn] [AID651156, Type: other]Casein kinase I isoform gamma-1 [gi:18202957]
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12
[SID103504607]
GSK_PKIS: CK1-g1 mean inhibition at 1 uM [Nanosyn] [AID651157, Type: other]Casein kinase I isoform gamma-1 [gi:18202957]
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13
[SID103504607]
GSK_PKIS: EPHB4 mean inhibition at 0.1 uM [Nanosyn] [AID651422, Type: other]Ephrin type-B receptor 4 [gi:19860819]
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14
[SID103504607]
GSK_PKIS: EPHB4 mean inhibition at 1 uM [Nanosyn] [AID651423, Type: other]Ephrin type-B receptor 4 [gi:19860819]
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15
[SID103504607]
GSK_PKIS: PKC-beta1 (splice variant) mean inhibition at 0.1 uM [Nanosyn] [AID651044, Type: other]Protein kinase C beta type [gi:20141488]
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16
[SID103504607]
GSK_PKIS: PKC-beta1 (splice variant) mean inhibition at 1 uM [Nanosyn] [AID651045, Type: other]Protein kinase C beta type [gi:20141488]
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17
[SID103504607]
GSK_PKIS: PKC-beta2 (splice variant) mean inhibition at 0.1 uM [Nanosyn] [AID651054, Type: other]Protein kinase C beta type [gi:20141488]
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18
[SID103504607]
GSK_PKIS: PKC-beta2 (splice variant) mean inhibition at 1 uM [Nanosyn] [AID651055, Type: other]Protein kinase C beta type [gi:20141488]
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19
[SID103504607]
GSK_PKIS: FER mean inhibition at 0.1 uM [Nanosyn] [AID651428, Type: other]Tyrosine-protein kinase Fer [gi:97536202]
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20
[SID103504607]
GSK_PKIS: FER mean inhibition at 1 uM [Nanosyn] [AID651429, Type: other]Tyrosine-protein kinase Fer [gi:97536202]
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