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Dronabinol (CID 16078) - Compound BioActivity Data
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BioActivity Outcomes:
Active(75)
 
 
Inactive(44)
 
 
Inconclusive(25)
 
 
Unspecified(169)
 
 
Top Targets:
7tm 4(15)
 
 
 
 
NR LBD AR(7)
 
 
 
NR LBD ER(7)
 
 
 
NR LBD GR(4)
 
 
NR LBD TR(3)
 
 
 
BioAssay Types:
Literature(231)
 
 
 
 
 
Confirmatory(52)
 
 
 
 
Summary(15)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(62)
 
 
 
 
Ki(39)
 
 
IC50(10)
 
 
EC50(5)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 312    Data Row: 313   Total Pages: 16   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103167825]
EC50 0.0015Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assay [AID406792, Type: Literature]Cannabinoid receptor 2 [gi:461697]
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2
[SID103167825]
IC50 0.0028Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 mins [AID636834, Type: Literature]Cannabinoid receptor 1 [gi:115562]
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3
[SID103167825]
Ki 0.0029Displacement of [3H]CP-55940 from human CB1 receptor [AID406791, Type: Literature]Cannabinoid receptor 1 [gi:115562]
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4
[SID103167825]
Ki 0.0033Binding affinity to human CB2 receptor [AID299499, Type: Literature]Cannabinoid receptor 2 [gi:461697]
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5
[SID103167825]
Ki 0.00388Displacement of [3H]-CP55,940 from human CB1 receptor transfected in CHOK1 cells [AID750731, Type: Literature]Cannabinoid receptor 1 [gi:115562]
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6
[SID103167825]
IC50 0.004Concentration required to inhibit electrically induced contractions in isolated mouse vas deferens preparation in vitro [AID138344, Type: Literature]
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7
[SID103167825]
IC50 0.004In vitro inhibition of electrically induced contractions in isolated mouse vas deferens (MVD) preparations. [AID132488, Type: confirmatory]
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8
[SID103167825]
IC50 0.0058Compound was evaluated for the inhibition of [3H]WIN-55212-2 binding in rat cerebellum membranes [AID48997, Type: confirmatory]
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9
[SID103167825]
IC50 0.0058Concentration of compound required to inhibit 50% of [3H]WIN-55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes. [AID49481, Type: Literature]
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10
[SID103167825]
Ki 0.0092Binding affinity to mouse CB2 receptor [AID299503, Type: Literature]Cannabinoid receptor 2 [gi:1345700]
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11
[SID103167825]
IC50 0.0095Displacement of [3H]CP55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 mins [AID636835, Type: Literature]Cannabinoid receptor 2 [gi:461697]
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12
[SID103167825]
Ki 0.01Displacement of [3H]-CP55,940 from human CB1 receptor expressed in HEK293 cells [AID646621, Type: Literature]Cannabinoid receptor 1 [gi:115562]
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13
[SID103167825]
EC50 0.011Effective concentration for inhibition of Cannabinoid receptor 1-mediated adenylyl cyclase activity using African green monkey (COS-7) cells transfected with the cDNA of rat CB1 receptor [AID49474, Type: Literature]
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14
[SID103167825]
EC50 0.017Agonist activity at human CB1 receptor expressed in HEK293 EBNA cells by [35S]GTPgamma binding assay [AID646622, Type: Literature]Cannabinoid receptor 1 [gi:115562]
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15
[SID103167825]
Ki 0.017Binding affinity to human CB1 receptor [AID299500, Type: Literature]Cannabinoid receptor 1 [gi:115562]
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16
[SID103167825]
Ki 0.02Binding affinity for cannabinoid receptor 2 [AID238321, Type: Literature]
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17
[SID103167825]
Ki 0.024Binding affinity to human CB2 receptor [AID646624, Type: Literature]Cannabinoid receptor 2 [gi:461697]
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18
[SID103167825]
Ki 0.025Binding affinity towards Cannabinoid receptor 2 using CP-55940 as radioligand in HEK293 EBNA cells [AID49845, Type: Literature]
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19
[SID103167825]
Ki 0.0285Binding affinity towards Cannabinoid receptor 1 using CP-55940 as radioligand in HEK293 EBNA cells [AID49314, Type: Literature]
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20
[SID103167825]
Ki 0.0322Binding affinity to Cannabinoid receptor 2 using African green monkey (COS-7) cells Chinese hamster ovary(CHO) cells transfected with the cDNA of human CB2 [AID49843, Type: Literature]
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