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5-hydroxyindole (CID 16054) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(819)
 
 
Inconclusive(15)
 
 
Unspecified(12)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
 
7TM GPCR Srsx(21)
 
 
alkPPc(16)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
BioAssay Types:
Screening(553)
 
 
 
 
 
Confirmatory(260)
 
 
 
 
 
Literature(26)
 
 
 
 
 
BioActivity Types:
Potency(171)
 
 
 
 
 
IC50(62)
 
 
 
 
 
EC50(10)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 782    Data Row: 857   Total Pages: 43   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID865950]
IC50 2.23A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag - Counter Screen [AID2501, Type: confirmatory]
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2
[SID865950]
Potency 8.1995A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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3
[SID103578866]
IC50 13Antimelanogenic activity in mouse B16 cells assessed as inhibition of intracellular melanin accumulation after 2 days [AID428335, Type: Literature]
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4
[SID865950]
Potency 14.1254qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen [AID2100, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
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5
[SID865950]
IC50 80.22Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents [AID1903, Type: confirmatory]large T antigen [Simian virus 40] [gi:297591903]
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6
[SID170482140]
IC50 2000Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Leukotriene A4 Hydrolase In Complex With Fragment 5- Hydroxyindole And Bestatin [gi:254839302]
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7
[SID170482140]
IC50 2000Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Leukotriene A4 Hydrolase In Complex With Fragment 5- Hydroxyindole And Bestatin [gi:254839302]
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8
[SID865950]
Counter Screen for Glucose-6-Phosphate Dehydrogenase-based Primary Assay [AID1020, Type: screening]glucose-6-phosphate dehydrogenase [Leuconostoc mesenteroides] [gi:149631]
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9
[SID865950]
Leishmania major promastigote HTS [AID1063, Type: screening]
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10
[SID865950]
Antagonist of Human D 1 Dopamine Receptor: qHTS [AID504652, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
View
11
[SID865950]
qHTS Assay for Tau Filament Binding [AID596, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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12
[SID103578866]
IC50 68Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formation [AID428332, Type: Literature]Tyrosinase [gi:152060989]
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13
[SID103578866]
IC50 1000Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE [AID420374, Type: Literature]Leukotriene A-4 hydrolase [gi:126353]
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14
[SID103578866]
EC50 1000Activity at human alpha-7 nACh receptor expressed in Xenopus laevis oocyte assessed as increase in acetylcholine-induced current [AID321284, Type: Literature]Neuronal acetylcholine receptor subunit alpha-7 [gi:2506127]
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15
[SID103578866]
IC50 2000Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupole mass spectrometry [AID420375, Type: Literature]Leukotriene A-4 hydrolase [gi:126353]
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16
[SID103578866]
Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formation at 100 uM [AID428333, Type: Literature]Tyrosinase [gi:152060989]
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17
[SID103578866]
Inhibition of catecholase activity of tyrosinase in human HMVII cells assessed as dopachrome formation at 100 uM [AID428334, Type: Literature]Tyrosinase [gi:401235]
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18
[SID865950]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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19
[SID865950]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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20
[SID103578866]
Antioxidant activity assessed as inhibition of ABTS free radical generation at 9 uM after 20 mins by UV spectrophotometric analysis relative to control [AID763541, Type: Literature]
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