Bookmark and Share
vinorelbine (CID 16051941) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(20)
 
 
Inactive(43)
 
 
Inconclusive(32)
 
 
Unspecified(2)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
 
NR LBD Fxr(4)
 
 
 
 
NR LBD VDR(4)
 
 
 
BioAssay Types:
Confirmatory(67)
 
 
 
 
Summary(24)
 
 
 
 
Literature(4)
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(85)
 
 
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 97    Data Row: 97   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103690232]
IC50 0.009Cytotoxicity against human A549 cells by sulforhodamine B assay [AID430357, Type: Literature]
View
2
[SID103690232]
IC50 0.009Cytotoxicity against human HeLa cells by sulforhodamine B assay [AID430358, Type: Literature]
View
3
[SID144205824]
Potency 0.0531qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
4
[SID144205824]
Potency 0.0596qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
5
[SID144205824]
Potency-Replicate_1 0.075qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
6
[SID144205824]
Potency-Replicate_1 0.0841qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
7
[SID144205824]
Potency-Replicate_1 0.1059qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
View
8
[SID144205824]
Ratio Potency (uM) 0.105909qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
View
9
[SID144205824]
Potency-Replicate_1 0.1188qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
10
[SID144205824]
Ratio Potency (uM) 0.989298qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
11
[SID144205824]
Potency-Replicate_1 1.1883qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
View
12
[SID144205824]
Potency-Replicate_1 1.5089qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
13
[SID144205824]
Potency-Replicate_1 1.8834qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
14
[SID144205824]
Potency-Replicate_1 2.371qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
View
15
[SID144205824]
ATAD5 Potency (uM) 3.22305qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
View
16
[SID144205824]
Potency-Replicate_1 4.7308qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
View
17
[SID144205824]
Potency 11.2202qHTS Assay for Identifying Gametocytocidal Compounds [AID743244, Type: confirmatory]
View
18
[SID170465330]
Potency-Replicate_1 26.6011qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
View
19
[SID170465330]
Potency-Replicate_1 29.847qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
View
20
[SID170465330]
qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743240, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View