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AGN-PC-00RCC4 (CID 16010689) - Compound BioActivity Data
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BioActivity Outcomes:
Active(15)
 
 
Inactive(592)
 
 
Inconclusive(10)
 
 
Unspecified(4)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
7TM GPCR Srsx(20)
 
 
 
B zip1(6)
 
 
 
Pyr redox dim(6)
 
 
PLDc mTdp1 2(6)
 
 
 
BioAssay Types:
Screening(379)
 
 
 
Confirmatory(219)
 
 
 
 
 
Literature(16)
 
 
 
 
BioActivity Types:
Potency(179)
 
 
 
 
 
IC50(30)
 
 
 
EC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 512    Data Row: 621   Total Pages: 32   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49730988]
IC50 1.86A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) [AID2391, Type: confirmatory]
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2
[SID163336489]
EC50 5Antiviral activity against Respiratory syncytial virus Long infected in human Hep2 cells assessed as reduction in virus-induced cytopathogenicity by Cell Titer-Glo assay [AID701507, Type: Literature]
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3
[SID99309100]
Average IC50 12.6A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (8) [AID504820, Type: confirmatory]
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4
[SID99309100]
IC50 13.16A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using purified and synthesized compounds [AID488972, Type: confirmatory]
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5
[SID49730988]
Potency 16.3601qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID49730988]
Potency 16.3601qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID24387235]
Potency 18.3564qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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8
[SID24387235]
Potency 23.1093qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID163336489]
CC50 31.5Cytotoxicity against human Hep2 cells by Cell Titer-Glo assay [AID701508, Type: Literature]
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10
[SID99309100]
Average CC50 33.4An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (8) [AID504818, Type: confirmatory]
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11
[SID99309100]
CC50 40.51An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using purified and synethesized compounds [AID488976, Type: confirmatory]
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12
[SID49730988]
CC50 42.94An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) [AID2410, Type: confirmatory]
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13
[SID99309100]
A Plaque Reduction Assay to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) [AID504830, Type: other]
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14
[SID93616802]
A Titer Reduction Assay to evaluate Selected Compounds as new Inhibitors of Respiratory Syncytial Virus (RSV) [AID449732, Type: other]
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15
[SID49730988]
IC50 uHTS absorbance assay for the identification of compounds that inhibit PHOSPHO1 [AID1565, Type: confirmatory]phosphoethanolamine/phosphocholine phosphatase isoform 1 [Homo sapiens] [gi:219689097]
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16
[SID163336489]
Selectivity index, ratio of CC50 for human Hep2 cells to EC50 for Respiratory syncytial virus Long infected in human Hep2 cells [AID701509, Type: Literature]
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17
[SID163336489]
Antiviral activity against Respiratory syncytial virus Long infected in human Hep2 cells assessed as log reduction in virus titer at 25 uM by virus plaque reduction assay [AID701510, Type: Literature]
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18
[SID49730988]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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19
[SID24387235]
HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]D(2) dopamine receptor isoform long [Homo sapiens] [gi:4503385]
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20
[SID49730988]
Potency 2.5119qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
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