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AGN-PC-00RB5A (CID 16009147) - Compound BioActivity Data
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BioActivity Outcomes:
Active(36)
 
 
Inactive(731)
 
 
Inconclusive(41)
 
 
Unspecified(3)
 
 
Top Targets:
7TM GPCR Srx(28)
 
 
7TM GPCR Srsx(22)
 
 
 
NR LBD PPAR(12)
 
 
 
Bcl-2 like(11)
 
 
ANK(10)
 
 
 
BioAssay Types:
Screening(501)
 
 
 
 
 
Confirmatory(284)
 
 
 
 
 
Literature(12)
 
 
BioActivity Types:
Potency(220)
 
 
 
 
 
IC50(39)
 
 
 
EC50(15)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 656    Data Row: 811   Total Pages: 41   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24385480]
Potency 5.8048qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID24385480]
Potency 8.1995qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID24813715]
Potency 10qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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4
[SID24385480]
Potency 11.2202qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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5
[SID24385480]
Potency 11.2202qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
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6
[SID24813715]
AbsAC26_uM 11.39Luciferase Reporter Cell Based HTS to identify inhibitors of N-linked Glycosylation Measured in Cell-Based System Using Plate Reader - 2146-01_Inhibitor_Dose_CherryPick_Activity [AID624491, Type: confirmatory]
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7
[SID24385480]
Potency 12.5893qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature [AID904, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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8
[SID24813715]
EC50_uM 17.26Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) [AID435004, Type: confirmatory]Hsf1 protein [Mus musculus] [gi:62740231]
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9
[SID24385480]
Potency 19.8723HBEC Cell Viability Secondary Assay for qHTS Assay for Epigenetic Modulators [AID493066, Type: confirmatory]
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10
[SID24813715]
AbsAC40_uM 21.96Sustained Induction of HSF-1 Measured in Cell-Based System Using Plate Reader - 2038-07_Activator_Dose_CherryPick_Activity [AID602296, Type: confirmatory]Hsf1 protein [Mus musculus] [gi:62740231]
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11
[SID24813715]
Potency 22.3872qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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12
[SID24813715]
Potency 23.1093qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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13
[SID24813715]
Potency 23.1093qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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14
[SID24385480]
Potency 28.0703H358 Cell Viability Secondary Assay for qHTS Assay for Epigenetic Modulators: Round 2 [AID493074, Type: confirmatory]
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15
[SID24385480]
Potency 28.1838qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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16
[SID24813715]
Heat Shock Factor-1 (HSF-1) Measured in Cell-Based System Using Plate Reader - 2038-01_Activator_SinglePoint_HTS_Activity [AID504408, Type: screening]
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17
[SID24813715]
Leishmania major promastigote HTS [AID1063, Type: screening]
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18
[SID24813715]
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate regulator of G-protein signaling 4 (RGS4) [AID463111, Type: screening]regulator of G-protein signaling 4 isoform 2 [Homo sapiens] [gi:5032039]
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19
[SID24813715]
HTS Assay for Peg3 Promoter Inhibitors [AID588405, Type: screening]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
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20
[SID24813715]
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) [AID1032, Type: screening]NCOA2 protein [Homo sapiens] [gi:62201602]
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