homonojirimycin (CID 159496) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(13)
 
 
Unspecified(9)
 
 
Top Targets:
GH31 MGAM SI..(10)
 
 
AmyAc Glg deb..(1)
 
 
Glyco hydro 3..(1)
 
 
BioAssay Types:
Literature(22)
 
 
 
BioActivity Types:
IC50(13)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 22    Data Row: 22   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103617394]
IC50 0.04Inhibitory activity measured against alpha-glucosidase of rice by colorimetric assay using the D-glucose oxidase-peroxidase method [AID37260, Type: Literature]
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2
[SID103617394]
IC50 0.08Inhibition of rat intestinal brush border membrane maltase [AID342793, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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3
[SID103617394]
IC50 0.1Inhibition of maltase in human Caco-2 cell model system after 2 hrs [AID342811, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
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4
[SID103617394]
IC50 0.1Inhibition of maltase in human Caco-2 cell model system after 2 hrs [AID342811, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
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5
[SID103617394]
IC50 0.1Inhibition of maltase in human Caco-2 cell model system after 2 hrs [AID342811, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
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6
[SID103617394]
IC50 0.11Inhibition of rabbit muscle amylo-1,6-glucosidase [AID342805, Type: Literature]Glycogen debranching enzyme [gi:544379]
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7
[SID103617394]
IC50 0.17Inhibition of rat intestinal brush border membrane sucrase [AID342797, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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8
[SID103617394]
IC50 0.17Inhibitory activity measured against alpha-glucosidase of rat intestinal sucrase by colorimetric assay using the D-glucose oxidase-peroxidase method [AID37291, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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9
[SID103617394]
IC50 0.26Inhibitory activity measured against alpha-glucosidase of rat liver lysosomal by colorimetric assay using the D-glucose oxidase-peroxidase method [AID37396, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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10
[SID103617394]
IC50 0.34Inhibitory activity measured against alpha-glucosidase of rat intestinal maltase by colorimetric assay using the D-glucose oxidase-peroxidase method [AID37290, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
View
11
[SID103617394]
IC50 0.7Inhibition of rat intestinal brush border membrane isomaltase [AID342795, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
View
12
[SID103617394]
IC50 0.7Inhibitory activity measured against alpha-glucosidase of rat intestinal isomaltase by colorimetric assay using the D-glucose oxidase-peroxidase method [AID37289, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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13
[SID103617394]
IC50 1Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
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14
[SID103617394]
IC50 1Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
View
15
[SID103617394]
IC50 1Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
View
16
[SID103617394]
IC50 8.4Inhibitory activity measured against alpha-glucosidase of rat liver ER glucosidase II by colorimetric assay using the D-glucose oxidase-peroxidase method [AID37395, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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17
[SID103617394]
IC50 34Inhibitory activity measured against trehalase of porcine kidney by colorimetric assay using the D-glucose oxidase-peroxidase method [AID210964, Type: Literature]
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18
[SID103617394]
 Inhibitory activity measured against trehalase of porcine kidney by colorimetric assay using the D-glucose oxidase-peroxidase method at 1000 uM [AID210965, Type: Literature]
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19
[SID103617394]
 Inhibition of rabbit glycogen phosphorylase B at 400 uM [AID342804, Type: Literature]
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20
[SID103617394]
 Antihyperglycemic effect in STZ-diabetic ddY mouse assessed as reduction in blood glucose level at 150 umol/kg, ip by glucose oxidase method [AID400363, Type: Literature]
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21
[SID103617394]
 Inhibitory activity measured against alpha-L-fucosidase of rat epididymis by colorimetric assay using the D-glucose oxidase-peroxidase method at 1000 uM [AID36965, Type: Literature]
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22
[SID103617394]
 Inhibitory activity measured against alpha-L-fucosidase of bovine epididymis by colorimetric assay using the D-glucose oxidase-peroxidase method at 1000 uM [AID36824, Type: Literature]
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23
[SID103617394]
 Inhibitory activity measured against alpha-galactosidase of coffee bean by colorimetric assay using the D-glucose oxidase-peroxidase method at 1000 uM [AID73342, Type: Literature]
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24
[SID103617394]
 Inhibitory activity measured against beta-galactosidase of bovine liver by colorimetric assay using the D-glucose oxidase-peroxidase method at 1000 uM [AID73345, Type: Literature]
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25
[SID103617394]
 Inhibitory activity measured against beta-galactosidase of rat intestinal lactase by colorimetric assay using the D-glucose oxidase-peroxidase method at 1000 uM [AID73348, Type: Literature]
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26
[SID103617394]
 Inhibition of human lysosomal beta-glucosidase at 1000 uM [AID342802, Type: Literature]Glucosylceramidase [gi:55584151]
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27
[SID103617394]
 Inhibition of human lysosomal beta-glucosidase at 1000 uM [AID342802, Type: Literature]Glucosylceramidase [gi:55584151]
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