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14-benzoylacenaphtho[1',2':4,5]pyrido[2,1-b][1,3]benzothiazol-13-ium (CID 15944971) - Compound BioActivity Data
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BioActivity Outcomes:
Active(141)
 
 
Inactive(528)
 
 
Inconclusive(59)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
 
7TM GPCR Srsx(23)
 
 
 
G-alpha(14)
 
 
 
 
Bcl-2 like(13)
 
 
 
Tryp SPc(7)
 
 
BioAssay Types:
Screening(468)
 
 
 
 
 
Confirmatory(233)
 
 
 
 
 
Literature(11)
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(161)
 
 
 
 
 
IC50(48)
 
 
 
 
EC50(12)
 
 
 
 
AC50(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 655    Data Row: 730   Total Pages: 37   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID22404228]
EC50_MICROM 0.06Dose Response of inhibitors of GRK2 binding with RNA aptamer, Cherry Pick 1 [AID504500, Type: confirmatory]beta-adrenergic receptor kinase 1 [Homo sapiens] [gi:148539876]
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2
[SID22404228]
Potency 0.4654Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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3
[SID22404228]
DR_EC50uM_Run1 0.543Leishmania major promastigote EC50 determinations [AID2008, Type: confirmatory]
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4
[SID22404228]
Potency 0.9285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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5
[SID22404228]
EC50 1.28A cytotoxicity screen of small molecule inhibitors of the PhoP regulon in Salmonella typhimurium identified in the primary screen [AID2253, Type: confirmatory]
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6
[SID22404228]
EC50 1.36A cytotoxicity screen of small molecule inhibitors of the PhoP regulon in Salmonella typhi identified in the primary screen [AID2252, Type: confirmatory]
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7
[SID22404228]
AC50_uM 2.052Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis [AID449756, Type: confirmatory]
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8
[SID22404228]
AC50_uM 2.257ATP-based Luminescence in the Absence of Cytokines Measured in Cell-Based System Using Plate Reader - 2061-06_Inhibitor_Dose_CherryPick [AID463229, Type: confirmatory]
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9
[SID22404228]
Potency 2.3109qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID22404228]
IC50 2.808High Throughput Screen to Identify Inhibitors of Mycobacterium tuberculosis H37Rv [AID1626, Type: confirmatory]
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11
[SID22404228]
Potency 4.4668qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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12
[SID22404228]
Potency 4.6109qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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13
[SID22404228]
Potency 6.012qHTS Assay for the Inhibitors of FEN1: Confirmatory Assay for Cherry-picked Compounds [AID720498, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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14
[SID22404228]
Potency 6.3096qHTS for Inhibitors of Vif-A3G Interactions: qHTS [AID602310, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3G [Homo sapiens] [gi:13399304]
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15
[SID22404228]
Potency 6.3096qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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16
[SID22404228]
Potency 7.6365qHTS for Inhibitors of WRN Helicase: Confirmatory Assay for Cherry-picked Compounds. [AID720497, Type: confirmatory]WRN [Homo sapiens] [gi:3719421]
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17
[SID22404228]
Potency 7.9433qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP) [AID1688, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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18
[SID22404228]
Potency 10qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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19
[SID22404228]
Potency 10qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction [AID1461, Type: confirmatory]neuropeptide S receptor isoform A [Homo sapiens] [gi:46395496]
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20
[SID22404228]
Potency 10qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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