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Paraquat (CID 15938) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(1)
 
 
Unspecified(163)
 
 
Top Targets:
7TM GPCR Srx(16)
 
 
7TM GPCR Srsx(15)
 
 
p450(8)
 
 
SLC6sbd DAT1(3)
 
 
NR LBD ER(2)
 
 
BioAssay Types:
Confirmatory(116)
 
 
Literature(38)
 
 
 
 
BioActivity Types:
IC50(116)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 170    Data Row: 170   Total Pages: 9   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103630533]
Phospholipidosis-positive literature compound observed in mouse [AID540238, Type: Literature]
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2
[SID103630533]
Increase in ompX-lacZ expression in Escherichia coli deltaompX mutant assessed as increase in beta-galactosidase activity after 60 mins relative to control [AID369249, Type: Literature]
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3
[SID103630533]
Increase in ompX-lacZ expression in Escherichia coli JM109 assessed as ompX upregulation after 60 mins relative to control [AID369250, Type: Literature]
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4
[SID103630533]
Increase in ompX-lacZ expression in Escherichia coli JM109 assessed as increase in beta-galactosidase activity after 60 mins relative to control [AID369251, Type: Literature]
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5
[SID103630533]
Increase in ompX-lacZ expression in Enterobacter aerogenes ATCC 15038 assessed as ompX upregulation after 60 mins relative to control [AID369252, Type: Literature]
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6
[SID103630533]
Increase in ompX-lacZ expression in Enterobacter aerogenes ATCC 15038 assessed as increase in beta-galactosidase activity after 60 mins relative to control [AID369253, Type: Literature]
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7
[SID103630533]
Induction of ompX transcription in SoxS-positive Escherichia coli K12 relative to control [AID369625, Type: Literature]
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8
[SID103630533]
Antibacterial activity against Escherichia coli KAM32 harboring plasmid pUC18 by CLSI broth microdilution method [AID571882, Type: Literature]
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9
[SID103630533]
Antibacterial activity against Escherichia coli KAM32 harboring plasmid pUC18 by CLSI broth microdilution method in presence of 25 ug/ml efflux pump inhibitor CCCP [AID571883, Type: Literature]
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10
[SID103630533]
Antibacterial activity against Escherichia coli KAM32 harboring recombinant plasmid pVBS1 encoding Acinetobacter baumannii abeS gene by CLSI broth microdilution method [AID571884, Type: Literature]
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11
[SID103630533]
Antibacterial activity against Escherichia coli KAM32 harboring recombinant plasmid pVBS1 encoding Acinetobacter baumannii abeS gene by CLSI broth microdilution method in presence of 25 ug/ml efflux pump inhibitor CCCP [AID571885, Type: Literature]
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12
[SID103630533]
Ratio of MIC for Escherichia coli KAM32 harboring plasmid pUC18 to MIC for Escherichia coli KAM32 harboring recombinant plasmid pVBS1 encoding Acinetobacter baumannii abeS gene [AID572058, Type: Literature]
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13
[SID103630533]
Antibacterial activity against Acinetobacter baumannii AC0037 by CLSI broth microdilution method [AID572059, Type: Literature]
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14
[SID103630533]
Antibacterial activity against abeS-deficient Acinetobacter baumannii AC0037 by CLSI broth microdilution method [AID572060, Type: Literature]
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15
[SID103630533]
Ratio of MIC for Acinetobacter baumannii AC0037 to MIC for abeS-deficient Acinetobacter baumannii AC0037 [AID572061, Type: Literature]
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16
[SID103630533]
Antibacterial activity against abeS sigma abeS-deficient Acinetobacter baumannii AC0037 by CLSI broth microdilution method [AID572062, Type: Literature]
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17
[SID103630533]
Antimicrobial activity against AcrAB-deficient Escherichia coli AG100AX harboring pBADomeganorM plasmid containing Neisseria gonorrhoeae multidrug efflux pump NorM after 18 to 24 hrs by two fold dilution method [AID572147, Type: Literature]
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18
[SID103630533]
Antimicrobial activity against AcrAB-deficient Escherichia coli AG100AX harboring pBAD plasmid after 18 to 24 hrs by two fold dilution method [AID572150, Type: Literature]
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19
[SID103630533]
Antimicrobial activity against AcrAB-deficient Escherichia coli AG100AX harboring pBADomegaydhE plasmid containing Escherichia coli multidrug efflux pump YdhE after 18 to 24 hrs by two fold dilution method [AID572151, Type: Literature]
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20
[SID103630533]
Literature-mined public compounds from Lowe et al phospholipidosis modelling dataset [AID588208, Type: Literature]
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