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BioActivity Data for Compound Mercaptoethanol (CID 1567)

BioActivity Outcomes:
Active(1)
 
 
Inactive(9)
 
 
Inconclusive(24)
 
 
Unspecified(30)
 
 
Top Targets:
DNA pol B 3(1)
 
 
BioAssay Types:
Literature(21)
 
 
 
BioAssay Categories:
In vitro(1)
 
 
In vivo(3)
 
 
 
Biochemical(20)
 
 
 
Toxicity(9)
 
 
Cell-based(3)
 
 
 
Organism-base..(2)
 
 
BioActivity Types:
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 64    Data Row: 64   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103562101]
IC50 Inhibition of metallo-beta-lactamase IMP-1 (unknown origin) [AID1128913, Type: Literature]
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2
[SID103562101]
Inhibition of carbonic anhydrase 9 catalytic domain assessed as residual activity at 10 mM [AID314757, Type: Literature]
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3
[SID103562101]
Inhibition of carbonic anhydrase 9 assessed as residual activity at 10 mM [AID314758, Type: Literature]
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4
[SID103562101]
Dissociation constant, pKa of the compound [AID637281, Type: Literature]
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5
[SID103562101]
Binding affinity to Enterobacteria phage T4 lysozyme L99A/M102H double mutant expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 2 mM at pH 5.4 by circular dichroism analysis [AID728442, Type: Literature]
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6
[SID8150097]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubU) [AID1593, Type: other]
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7
[SID8150097]
Assay to identify inhibitors of polyglutamine-induced caspase-3 activation (CASP3) [AID1583, Type: other]
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8
[SID8150097]
Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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9
[SID8150097]
Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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10
[SID8150097]
Screening of compounds showing protective effect against cell death induced by familial amyotrophic lateral sclerosis (FALS)-linked mutantsuperoxide dismutase 1 (SOD1) (ALSOD1) [AID1605, Type: other]
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11
[SID8150097]
Screen for compounds that correct neuronal dysfunction without cell death as induced by the expression of polyglutamine-expanded, N-terminal huntingtin in C. elegans mechanosensory neurons (HDELENEU) [AID1599, Type: other]
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12
[SID8150097]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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13
[SID8150097]
Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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14
[SID8150097]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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15
[SID8150097]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubH) [AID1616, Type: other]
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16
[SID103562101]
Inhibition of carbonic anhydrase 2 assessed as residual activity at 0.001 mM [AID314741, Type: Literature]
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17
[SID103562101]
Inhibition of carbonic anhydrase 9 catalytic domain assessed as residual activity at 0.001 mM [AID314742, Type: Literature]
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18
[SID103562101]
Inhibition of carbonic anhydrase 9 assessed as residual activity at 0.001 mM [AID314743, Type: Literature]
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19
[SID103562101]
Inhibition of carbonic anhydrase 2 assessed as residual activity at 0.01 mM [AID314744, Type: Literature]
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20
[SID103562101]
Inhibition of carbonic anhydrase 9 catalytic domain assessed as residual activity at 0.01 mM [AID314745, Type: Literature]
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