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BIRB 796 (CID 156422) - Compound BioActivity Data
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BioActivity Outcomes:
Active(427)
 
 
Inactive(336)
 
 
Inconclusive(28)
 
 
Unspecified(1374)
 
 
Top Targets:
PKc(102)
 
 
 
 
PKc like(99)
 
 
 
 
STKc AGC(47)
 
 
 
PTKc Abl(38)
 
 
 
 
PTKc EGFR(28)
 
 
 
 
BioAssay Types:
Literature(1399)
 
 
 
 
Confirmatory(738)
 
 
 
 
 
Summary(24)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Kd(898)
 
 
 
 
IC50(784)
 
 
 
Potency(109)
 
 
 
 
EC50(6)
 
 
Ki(5)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1958    Data Row: 2165   Total Pages: 109   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103320031]
Kd 4.6e-05Kd value and murine Mitogen-activated protein kinase p38 alpha complex was calculated [AID127268, Type: Literature]
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2
[SID103320031]
Kd 4.6e-05Dissociation constant at Tref against human Mitogen-activated protein kinase p38 alpha [AID127252, Type: Literature]Mitogen-activated protein kinase 14 [gi:2499600]
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3
[SID103320031]
Kd 9.7e-05Binding affinity against human Mitogen-activated protein kinase p38 kinase evaluated by exchange curve [AID127075, Type: Literature]Mitogen-activated protein kinase 14 [gi:2499600]
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4
[SID103320031]
Ki 9.7e-05Inhibition of p38alpha [AID512564, Type: Literature]
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5
[SID103320031]
Kd 9.7e-05Binding affinity against human Mitogen-activated protein kinase p38 kinase evaluated by exchange curve [AID127075, Type: Literature]Mitogen-activated protein kinase 12 [gi:2851522]
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6
[SID103320031]
Kd 9.7e-05Binding affinity against human Mitogen-activated protein kinase p38 kinase evaluated by exchange curve [AID127075, Type: Literature]Mitogen-activated protein kinase 13 [gi:6685642]
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7
[SID103320031]
Kd 9.7e-05Binding affinity against human Mitogen-activated protein kinase p38 kinase evaluated by exchange curve [AID127075, Type: Literature]Mitogen-activated protein kinase 11 [gi:134047835]
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8
[SID103320031]
Kd 9.8e-05Binding affinity to full-length GST-tagged p38alpha by surface plasmon resonance assay [AID516348, Type: Literature]
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9
[SID103320031]
Kd 9.8e-05Binding affinity for Mitogen-activated protein kinase p38 alpha [AID127260, Type: Literature]
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10
[SID103320031]
Ki 0.0001Inhibition of p38V kinase stie 3 delta 296-301 mutant [AID513132, Type: Literature]
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11
[SID103320031]
Kd 0.0001Binding affinity to p38alpha by exchange curve binding kinetic analysis [AID353469, Type: Literature]
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12
[SID103320031]
Kd 0.0001Dissociation constant at Tm against human Mitogen-activated protein kinase p38 alpha (fluorescence exchange curve) [AID127251, Type: Literature]Mitogen-activated protein kinase 14 [gi:2499600]
View
13
[SID46392387]
Kd 0.0001Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Human P38 Map Kinase In Complex With Birb 796 [gi:20151072]
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14
[SID46392387]
Kd 0.0001Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Human P38 Map Kinase In Complex With Birb 796 [gi:20151072]
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15
[SID103320031]
Kd 0.00016Inhibition of p38alpha [AID501375, Type: Literature]
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16
[SID103320031]
Kd 0.00024Average Binding Constant for p38-alpha; NA=Not Active at 10 uM [AID256656, Type: Literature]Mitogen-activated protein kinase 14 [gi:2499600]
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17
[SID103320031]
Kd 0.00037Binding constant for full-length p38-alpha [AID435181, Type: Literature]Mitogen-activated protein kinase 14 [gi:2499600]
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18
[SID103320031]
Kd 0.00045Binding constant for p38-alpha kinase domain [AID624714, Type: Literature]Mitogen-activated protein kinase 14 [gi:2499600]
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19
[SID103320031]
Kd 0.001Binding affinity to p38alpha MAPK by surface plasmon resonance method [AID639673, Type: Literature]
View
20
[SID103320031]
Kd 0.0013Dissociation constant at Tm against human Mitogen-activated protein kinase p38 alpha [AID127249, Type: Literature]Mitogen-activated protein kinase 14 [gi:2499600]
View