Canertinib (CID 156414) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(322)
 
 
Inactive(166)
 
 
Inconclusive(3)
 
 
Unspecified(542)
 
 
Top Targets:
PKc(110)
 
 
 
 
PKc like(75)
 
 
 
 
STKc AGC(64)
 
 
 
 
PTKc Abl(40)
 
 
 
 
PTKc EGFR(35)
 
 
BioAssay Types:
Literature(922)
 
 
 
 
Confirmatory(103)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Kd(879)
 
 
 
 
IC50(24)
 
 
 
Potency(13)
 
 
 
 
EC50(2)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 941    Data Row: 1033   Total Pages: 21   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103202250]
Kd 0.0001Binding constant for EGFR(T790M) kinase domain [AID625007, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
2
[SID103202250]
Kd 0.0001Binding constant for EGFR(T790M) kinase domain [AID625007, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
3
[SID103202250]
Kd 0.0001Binding constant for EGFR(T790M) kinase domain [AID625007, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
4
[SID103202250]
Kd 0.00013Binding constant for EGFR(G719C) kinase domain [AID624998, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
5
[SID103202250]
Kd 0.00013Binding constant for EGFR(G719C) kinase domain [AID624998, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
6
[SID103202250]
Kd 0.00013Binding constant for EGFR(G719C) kinase domain [AID624998, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
7
[SID103202250]
Kd 0.00013Binding constant for EGFR(G719C) kinase domain [AID435157, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
8
[SID103202250]
Kd 0.00013Binding constant for EGFR(G719C) kinase domain [AID435157, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
9
[SID103202250]
Kd 0.00013Binding constant for EGFR(G719C) kinase domain [AID435157, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
10
[SID103202250]
Kd 0.00017Binding constant for EGFR(L747-E749del, A750P) kinase domain [AID435652, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
11
[SID103202250]
Kd 0.00017Binding constant for EGFR(L747-E749del, A750P) kinase domain [AID435652, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
12
[SID103202250]
Kd 0.00017Binding constant for EGFR(L747-E749del, A750P) kinase domain [AID435652, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
13
[SID103202250]
Kd 0.00017Binding constant for EGFR(L747-E749del, A750P) kinase domain [AID625000, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
14
[SID103202250]
Kd 0.00017Binding constant for EGFR(L747-E749del, A750P) kinase domain [AID625000, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
15
[SID103202250]
Kd 0.00017Binding constant for EGFR(L747-E749del, A750P) kinase domain [AID625000, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
16
[SID103202250]
Kd 0.00019Binding constant for EGFR kinase domain [AID624996, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
17
[SID103202250]
Kd 0.00019Binding constant for EGFR kinase domain [AID624996, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
18
[SID103202250]
Kd 0.00019Binding constant for EGFR kinase domain [AID624996, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
19
[SID103202250]
Kd 0.00019Binding constant for EGFR(S752-I759del) kinase domain [AID435792, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
20
[SID103202250]
Kd 0.00019Binding constant for EGFR(S752-I759del) kinase domain [AID435792, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
21
[SID103202250]
Kd 0.00019Binding constant for EGFR(S752-I759del) kinase domain [AID435792, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
22
[SID103202250]
Kd 0.00019Binding constant for EGFR kinase domain [AID435156, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
23
[SID103202250]
Kd 0.00019Binding constant for EGFR kinase domain [AID435156, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
24
[SID103202250]
Kd 0.00019Binding constant for EGFR kinase domain [AID435156, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
25
[SID103202250]
Kd 0.00019Binding constant for EGFR(G719S) kinase domain [AID624999, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
26
[SID103202250]
Kd 0.00019Binding constant for EGFR(G719S) kinase domain [AID624999, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
27
[SID103202250]
Kd 0.00019Binding constant for EGFR(G719S) kinase domain [AID624999, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
28
[SID103202250]
Kd 0.00019Binding constant for EGFR(G719S) kinase domain [AID435402, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
29
[SID103202250]
Kd 0.00019Binding constant for EGFR(G719S) kinase domain [AID435402, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
30
[SID103202250]
Kd 0.00019Binding constant for EGFR(G719S) kinase domain [AID435402, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
31
[SID103202250]
Kd 0.00019Binding constant for EGFR(S752-I759del) kinase domain [AID625006, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
32
[SID103202250]
Kd 0.00019Binding constant for EGFR(S752-I759del) kinase domain [AID625006, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
33
[SID103202250]
Kd 0.00019Binding constant for EGFR(S752-I759del) kinase domain [AID625006, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
34
[SID103202250]
Kd 0.00022Binding constant for EGFR(L861Q) kinase domain [AID625005, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
35
[SID103202250]
Kd 0.00022Binding constant for EGFR(L861Q) kinase domain [AID625005, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
36
[SID103202250]
Kd 0.00022Binding constant for EGFR(L861Q) kinase domain [AID625005, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
37
[SID103202250]
Kd 0.00022Binding constant for EGFR(L861Q) kinase domain [AID435907, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
38
[SID103202250]
Kd 0.00022Binding constant for EGFR(L861Q) kinase domain [AID435907, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
39
[SID103202250]
Kd 0.00022Binding constant for EGFR(L861Q) kinase domain [AID435907, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
40
[SID103202250]
Kd 0.00024Binding constant for EGFR(L858R) kinase domain [AID435525, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
41
[SID103202250]
Kd 0.00024Binding constant for EGFR(L858R) kinase domain [AID435525, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
42
[SID103202250]
Kd 0.00024Binding constant for EGFR(L858R) kinase domain [AID435525, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
43
[SID103202250]
Kd 0.00024Binding constant for EGFR(L858R) kinase domain [AID625003, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
44
[SID103202250]
Kd 0.00024Binding constant for EGFR(L858R) kinase domain [AID625003, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
45
[SID103202250]
Kd 0.00024Binding constant for EGFR(L858R) kinase domain [AID625003, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
46
[SID103202250]
Kd 0.00026Binding constant for EGFR(E746-A750del) kinase domain [AID435791, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
47
[SID103202250]
Kd 0.00026Binding constant for EGFR(E746-A750del) kinase domain [AID435791, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
48
[SID103202250]
Kd 0.00026Binding constant for EGFR(E746-A750del) kinase domain [AID435791, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
49
[SID103202250]
Kd 0.00026Binding constant for EGFR(L747-S752del, P753S) kinase domain [AID435653, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
50
[SID103202250]
Kd 0.00026Binding constant for EGFR(L747-S752del, P753S) kinase domain [AID435653, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View