Bookmark and Share
Capsaicin (CID 1548943) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(62)
 
 
Inactive(998)
 
 
Inconclusive(111)
 
 
Unspecified(318)
 
 
Top Targets:
7tm 4(69)
 
 
 
ANK(41)
 
 
 
 
 
NR LBD TR(22)
 
 
 
 
NR LBD AR(21)
 
 
 
 
NR LBD PPAR(20)
 
 
 
BioAssay Types:
Confirmatory(708)
 
 
 
 
 
Screening(336)
 
 
 
Literature(161)
 
 
 
 
 
Summary(39)
 
 
 
 
BioActivity Types:
Potency(559)
 
 
 
 
 
IC50(136)
 
 
 
 
 
EC50(21)
 
 
Ki(9)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1081    Data Row: 1489   Total Pages: 75   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103248360]
EC50 0.00251Agonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as increase in intracellular calcium levels by fluorimetric assay [AID478379, Type: Literature]Transient receptor potential cation channel subfamily V member 1 [gi:296452849]
View
2
[SID103248360]
EC50 0.0039Agonist activity at human TRPV1 ion channel expressed in HEK293 cells assessed as calcium influx by fluo-4-Am-based fluorimetry [AID644962, Type: Literature]Transient receptor potential cation channel subfamily V member 1 [gi:296452849]
View
3
[SID103248360]
Ki 0.006Binding affinity to human recombinant TRPV1 [AID538418, Type: Literature]Transient receptor potential cation channel subfamily V member 1 [gi:296452849]
View
4
[SID103248360]
IC50 0.019Binding affinity to rat TRPV1 [AID538419, Type: Literature]Transient receptor potential cation channel subfamily V member 1 [gi:71164787]
View
5
[SID103248360]
EC50 0.02Agonist activity at human recombinant TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level [AID353804, Type: Literature]Transient receptor potential cation channel subfamily V member 1 [gi:296452849]
View
6
[SID103248360]
EC50 0.03In vitro agonist activity, increased [Ca2+] influx, at vanilloid receptor of rat dorsal root ganglia [AID218163, Type: Literature]Transient receptor potential cation channel subfamily V member 1 [gi:71164787]
View
7
[SID103248360]
EC50 0.03In vitro agonist activity, increased [Ca2+] influx, at vanilloid receptor of rat dorsal root ganglia [AID218163, Type: Literature]Transient receptor potential cation channel subfamily V member 2 [gi:62901124]
View
8
[SID103248360]
EC50 0.03In vitro agonist activity, increased [Ca2+] influx, at vanilloid receptor of rat dorsal root ganglia [AID218163, Type: Literature]Transient receptor potential cation channel subfamily V member 4 [gi:62901120]
View
9
[SID103248360]
EC50 0.04Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level [AID452447, Type: Literature]Transient receptor potential cation channel subfamily V member 1 [gi:296452849]
View
10
[SID103248360]
EC50 0.04Agonist activity at human recombinant TRPV1 expressed in human HEK293 cells [AID292699, Type: Literature]Transient receptor potential cation channel subfamily V member 1 [gi:296452849]
View
11
[SID103248360]
EC50 0.0448In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells [AID218314, Type: Literature]Transient receptor potential cation channel subfamily V member 1 [gi:71164787]
View
12
[SID103248360]
EC50 0.0448Agonist activity at rat TRPV1 receptor expressed in CHO cells assessed as calcium uptake [AID345832, Type: Literature]Transient receptor potential cation channel subfamily V member 1 [gi:71164787]
View
13
[SID124890089]
Potency 0.0912qHTS Assay for Compounds that Act as Agonists of the Vanilloid Receptor 1: Hit Validation in Parental Cell Line Calcium Assay [AID623960, Type: confirmatory]transient receptor potential cation channel subfamily V member 1 [Homo sapiens] [gi:74315350]
View
14
[SID103248360]
EC50 0.26In vitro effective dose for contraction of guinea pig ileum [AID73731, Type: Literature]
View
15
[SID103248360]
EC50 0.26Effective concentration for guinea pig ileum contraction in an in vitro assay [AID73732, Type: Literature]
View
16
[SID103248360]
EC50 0.26In vitro contraction in guinea pig ileum equivalent to 50% capsaicin response [AID73895, Type: Literature]
View
17
[SID103248360]
EC50 0.3Compound tested in vitro for [Ca2+] influx into neonatal rat dorsal root ganglia (DRG) [AID175476, Type: Literature]
View
18
[SID103248360]
EC50 0.3In vitro agonist activity against [Ca2+] uptake in neonatal rat cultured spinal sensory neurons [AID175840, Type: Literature]
View
19
[SID103248360]
EC50 0.3In vitro effective concentration for [Ca2+] uptake and accumulation of [Ca2+] in neonatal rat cultured spinal sensory neurons [AID175843, Type: Literature]
View
20
[SID103248360]
EC50 0.3In vitro effective concentration for [Ca2+] uptake into dorsal root ganglia neurones in culture [AID175848, Type: Literature]
View