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Digoxigenin (CID 15478) - Compound BioActivity Data
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BioActivity Outcomes:
Active(81)
 
 
Inactive(430)
 
 
Inconclusive(11)
 
 
Unspecified(17)
 
 
Top Targets:
7tm 4(34)
 
 
 
Death TRAILR..(12)
 
 
 
 
Esterase lipa..(5)
 
 
ANK(5)
 
 
 
CAP ED(5)
 
 
BioAssay Types:
Screening(363)
 
 
 
 
Confirmatory(134)
 
 
 
 
 
Literature(33)
 
 
 
 
BioActivity Types:
Potency(100)
 
 
 
 
 
IC50(20)
 
 
 
 
AC50(7)
 
 
 
 
Kd(6)
 
 
Ki(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 481    Data Row: 539   Total Pages: 27   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID208013331]
Kd 0.006Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]
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2
[SID208013331]
Kd 0.006Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]
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3
[SID46392439]
Kd 0.0302Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Engineered Lipocalin Diga16 In Complex With Digoxigenin [gi:33357289]
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4
[SID46392439]
Kd 0.0302Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Engineered Lipocalin Diga16 In Complex With Digoxigenin [gi:33357289]
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5
[SID56463065]
IC50 0.05A Cell-Based Confirmatory Screen for Compounds that Inhibit VEEV, TC-83 [AID588727, Type: confirmatory]
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6
[SID208013528]
Kd 0.168Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]
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7
[SID208013528]
Kd 0.168Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]
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8
[SID103333480]
IC50 0.3175Cytotoxicity against human TK10 cells after 48 hrs by SRB assay [AID399010, Type: Literature]
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9
[SID56463065]
AbsAC35_uM 0.373HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_CherryPick_Activity_Set3 [AID720589, Type: confirmatory]
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10
[SID103333480]
IC50 0.4161Cytotoxicity against human UACC62 cells after 48 hrs by SRB assay [AID399012, Type: Literature]
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11
[SID56463065]
Potency 0.4611Nrf2 qHTS screen for inhibitors: Nrf2 A549 ARE-Fluc Confirmation Assay for Hit Validation [AID720524, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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12
[SID56463065]
Potency 0.4611Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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13
[SID103333480]
IC50 0.507Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay [AID399011, Type: Literature]
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14
[SID56463065]
Potency 0.5623qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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15
[SID56463065]
IC50_Mean 0.58Dose response counterscreen of uHTS chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation in a HEK-293T cell line using a luminescence assay [AID489041, Type: confirmatory]
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16
[SID56463065]
AC50_uM 0.654Dose Response HTS Screen to Identify Cytotoxic Compounds of HMLE_sh_eGFP [AID463074, Type: confirmatory]
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17
[SID56463065]
Potency 0.8199qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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18
[SID56463065]
AbsAC35_uM 1Luminescence Cell-Based Primary HTS to identify inhibitors of the oncoprotein EWS/Fli transcriptional activity Measured in Cell-Based System Using Plate Reader - 7014-01_Inhibitor_Dose_CherryPick_Activity [AID686920, Type: confirmatory]
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19
[SID56463065]
AbsAC35_uM 1.1Luminescence cell-based Retest at Dose assay to determine EWS/Fli1 dependent A673 mammalian cell cytotoxity Measured in Cell-Based System Using Plate Reader - 7014-03_Inhibitor_Dose_CherryPick_Activity [AID720587, Type: confirmatory]
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20
[SID56463065]
Potency 1.122qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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