tributyltin (CID 15096) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(66)
 
 
Inactive(10)
 
 
Inconclusive(15)
 
 
Unspecified(2)
 
 
Top Targets:
NR LBD PPAR(5)
 
 
 
NR LBD TR(4)
 
 
 
NR LBD AR(2)
 
 
NR LBD ER(2)
 
 
 
NR LBD Fxr(2)
 
 
 
BioAssay Types:
Confirmatory(80)
 
 
 
 
Literature(3)
 
 
 
BioActivity Types:
Potency(26)
 
 
 
 
IC50(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 85    Data Row: 93   Total Pages: 2   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103740007]
IC50 0.04Cytotoxicity against HEK293 cells after 24 hrs by MTT assay [AID468472, Type: Literature]
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2
[SID103740007]
MIC 0.38Antimicrobial activity against Candida albicans ATCC 18804 after 48 hrs [AID468471, Type: Literature]
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3
[SID26757603]
Potency 0.3981qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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4
[SID26757603]
Potency 0.3981qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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5
[SID26757603]
Potency 0.3981qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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6
[SID26757603]
Potency 24.3365qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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7
[SID26757603]
Potency 24.3365qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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8
[SID26757603]
Potency 24.3365qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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9
[SID26757603]
Potency 24.3365qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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10
[SID26757603]
Potency 35.4813qHTS assay for small molecule antagonists of farnesoid X receptor signaling [AID588526, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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11
[SID26757603]
Potency 35.4813qHTS assay for small molecule antagonists of farnesoid X receptor signaling [AID588526, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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12
[SID26757603]
Potency 35.4813qHTS assay for small molecule antagonists of farnesoid X receptor signaling [AID588526, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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13
[SID26757603]
Potency 35.4813qHTS assay for small molecule antagonists of farnesoid X receptor signaling [AID588526, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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14
[SID26757603]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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15
[SID26757603]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
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16
[SID26757603]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
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17
[SID26757603]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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18
[SID26757603]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_8, Type: other]
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19
[SID26757603]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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20
[SID26757603]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_5, Type: other]
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21
[SID26757603]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
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22
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the NCI-H460 Non-Small Cell Lung cell line [AID7, Type: confirmatory]
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23
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the HOP-62 Non-Small Cell Lung cell line [AID9, Type: confirmatory]
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24
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the NCI-H322M Non-Small Cell Lung cell line [AID5, Type: confirmatory]
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25
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the NCI-H226 Non-Small Cell Lung cell line [AID3, Type: confirmatory]
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26
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line [AID1, Type: confirmatory]
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27
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line [AID13, Type: confirmatory]
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28
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the EKVX Non-Small Cell Lung cell line [AID21, Type: confirmatory]
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29
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the LOX IMVI Melanoma cell line [AID23, Type: confirmatory]
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30
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the M14 Melanoma cell line [AID25, Type: confirmatory]
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31
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the M19-MEL Melanoma cell line [AID27, Type: confirmatory]
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32
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line [AID29, Type: confirmatory]
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33
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the UACC-62 Melanoma cell line [AID31, Type: confirmatory]
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34
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the UACC-257 Melanoma cell line [AID33, Type: confirmatory]
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35
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-2 Melanoma cell line [AID35, Type: confirmatory]
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36
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line [AID37, Type: confirmatory]
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37
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-28 Melanoma cell line [AID39, Type: confirmatory]
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38
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the SF-268 Central Nervous System cell line [AID45, Type: confirmatory]
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39
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the SF-295 Central Nervous System cell line [AID47, Type: confirmatory]
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40
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the XF 498 Central Nervous System cell line [AID51, Type: confirmatory]
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41
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the SNB-19 Central Nervous System cell line [AID53, Type: confirmatory]
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42
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the SNB-75 Central Nervous System cell line [AID55, Type: confirmatory]
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43
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the SNB-78 Central Nervous System cell line [AID57, Type: confirmatory]
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44
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the U251 Central Nervous System cell line [AID59, Type: confirmatory]
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45
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the DMS 114 Small Cell Lung cell line [AID63, Type: confirmatory]
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46
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the HT29 Colon cell line [AID65, Type: confirmatory]
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47
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the COLO 205 Colon cell line [AID67, Type: confirmatory]
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48
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the DLD-1 Colon cell line [AID69, Type: confirmatory]
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49
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the HCT-15 Colon cell line [AID71, Type: confirmatory]
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50
[SID84509]
 NCI human tumor cell line growth inhibition assay. Data for the KM12 Colon cell line [AID73, Type: confirmatory]
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