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2,4-Dinitrophenol (CID 1493) - Compound BioActivity Data
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BioActivity Outcomes:
Active(35)
 
 
Inactive(742)
 
 
Inconclusive(97)
 
 
Unspecified(983)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD AR(16)
 
 
 
 
NR LBD ER(16)
 
 
 
7TM GPCR Srx(14)
 
 
 
NR LBD TR(12)
 
 
 
BioAssay Types:
Confirmatory(418)
 
 
 
 
 
Screening(365)
 
 
 
 
Summary(48)
 
 
 
 
Literature(39)
 
 
 
 
BioActivity Types:
Potency(396)
 
 
 
 
 
IC50(18)
 
 
 
 
EC50(5)
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1686    Data Row: 1857   Total Pages: 93   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210350]
Potency-Replicate_1 0.5448qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144208660]
Potency-Replicate_1 0.6887qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
3
[SID144210350]
Ratio Potency (uM) 1.00676qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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4
[SID47193722]
Potency 2.3053qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation. [AID588397, Type: confirmatory]
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5
[SID144208660]
Ratio Potency (uM) 2.96043qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
View
6
[SID17389906]
Potency 6.6824qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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7
[SID144210350]
Potency-Replicate_1 10.8707qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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8
[SID144208660]
Potency-Replicate_1 10.915qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
View
9
[SID103173306]
IC50 15.851Cytotoxicity against human MIA PaCa2 cells after 4 hrs by MTT assay [AID303043, Type: Literature]
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10
[SID17389906]
Potency 21.1317qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 1 hr assay [AID651754, Type: confirmatory]
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11
[SID144210350]
Ratio Potency (uM) 21.6899qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
View
12
[SID103173306]
IC50 22.101Cytotoxicity against human MIA PaCa2 cells after 72 hrs by MTT assay [AID303044, Type: Literature]
View
13
[SID17389906]
Potency 22.3872VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
View
14
[SID144208660]
Potency-Replicate_1 24.4355qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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15
[SID144210350]
Potency-Replicate_1 27.306qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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16
[SID144208660]
Potency-Replicate_1 27.4171qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
View
17
[SID144210350]
Potency-Replicate_1 30.6379qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
View
18
[SID144208660]
Potency-Replicate_1 30.7625qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
View
19
[SID144208660]
Potency-Replicate_1 30.7625qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
View
20
[SID17389906]
Potency 37.578qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 5 hr assay [AID651755, Type: confirmatory]
View