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2,4-Dichlorophenoxyacetic Acid (CID 1486) - Compound BioActivity Data
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BioActivity Outcomes:
Inactive(830)
 
 
Inconclusive(49)
 
 
Unspecified(26)
 
 
Top Targets:
NR LBD PPAR(26)
 
 
 
NR LBD ER(18)
 
 
 
NR LBD AR(18)
 
 
 
NR LBD TR(16)
 
 
7TM GPCR Srx(14)
 
 
BioAssay Types:
Confirmatory(443)
 
 
 
 
Screening(351)
 
 
Summary(48)
 
 
 
Literature(25)
 
 
 
BioActivity Types:
Potency(427)
 
 
 
 
IC50(20)
 
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 702    Data Row: 905   Total Pages: 19   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103434332]
IC50 50Antagonist activity at human T1R2/T1R3 receptor expressed in HEK293E cells assessed as inhibition of sucralose-induced intracellular calcium mobilization [AID439612, Type: Literature]
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2
[SID103434332]
IC50 180Phytotoxicity against Amaranthus hypochondriacus assessed as inhibition of radicle elongation by petri dish bioassay [AID334616, Type: Literature]
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3
[SID103434332]
IC50 180Phytogrowth-inhibitory activity against Amaranthus hypochondriacus assessed as inhibition of seedling growth [AID377853, Type: Literature]
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4
[SID103434332]
IC50 180Phytotoxicity against Amaranthus hypochondriacus assessed as inhibition of radicle elongation [AID380384, Type: Literature]
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5
[SID103434332]
IC50 200Phytotoxicity against Amaranthus hypochondriacus seedlings assessed as inhibition of radical growth at 28 degC by petridish assay [AID355713, Type: Literature]
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6
[SID103434332]
IC50 220Phytotoxicity against Echinochloa crus-galli assessed as inhibition of radicle elongation by petri dish bioassay [AID334617, Type: Literature]
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7
[SID103434332]
IC50 230Phytogrowth-inhibitory activity against Echinochloa crusgalli assessed as inhibition of seedling germination [AID377854, Type: Literature]
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8
[SID103434332]
IC50 230Phytogrowth-inhibitory activity against Echinochloa crusgalli assessed as inhibition of seedling growth [AID377856, Type: Literature]
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9
[SID103434332]
IC50 880Phytotoxicity against Echinochloa crusgalli assessed as inhibition of radicle elongation [AID380385, Type: Literature]
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10
[SID103434332]
IC50 880Phytogrowth-inhibitory activity against Amaranthus hypochondriacus assessed as inhibition of seedling germination [AID377855, Type: Literature]
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11
[SID103434332]
Stimulation of Echinochloa crus-galli radicle growth at 1 ug/ml incubated in dark at 27 degC measured after 48 hrs relative to control [AID338476, Type: Literature]
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12
[SID103434332]
Stimulation of Amaranthus hypochondriacus radicle growth at 1 ug/ml incubated in dark at 27 degC measured after 24 hrs relative to control [AID338477, Type: Literature]
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13
[SID103434332]
Solubility of Deoxyhemoglobin S (dHbS) concentration after addition dithionite as control [AID21143, Type: Literature]
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14
[SID103434332]
Solubility of Haemoglobin S (HbS) concentration after addition of acid and dithionite [AID21145, Type: Literature]
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15
[SID103434332]
Solubility ratio ([HbS+drug (10 mM)]/[HbS-drug]) [AID22012, Type: Literature]
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16
[SID103434332]
Solubility ratio ([HbS+drug (20 mM)]/[HbS-drug] [AID22013, Type: Literature]
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17
[SID103434332]
Solubility ratio ([HbS+drug (40 mM)]/[HbS-drug]) [AID22148, Type: Literature]
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18
[SID103434332]
Solubility ratio ([HbS+drug (5 mM)]/[HbS-drug]) [AID22149, Type: Literature]
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19
[SID103434332]
Stimulation of hypocotyls elongation in rape after 3 days [AID307157, Type: Literature]
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20
[SID103434332]
Stimulation of cytyledon expansion in cucumber after 3 days [AID307158, Type: Literature]
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21
[SID103434332]
Stimulation of coleoptiles growth in common wheat after 18 to 20 hrs [AID307159, Type: Literature]
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22
[SID56314831]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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23
[SID103434332]
TP_TRANSPORTER: inhibition of PAH uptake (PAH: 50 uM, 2,4-D: 1000 uM) in Xenopus laevis oocytes [AID679399, Type: other]Solute carrier family 22 member 6 [gi:74762955]
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24
[SID103434332]
TP_TRANSPORTER: inhibition of (Ochratoxin A: 0.5uM) of 2,4-dichlorophenoxyacetic acid at a concentration of 100uM in Oat5-expressing oocytes [AID678848, Type: other]Putative organic anion transporter 5 [gi:81891297]
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25
[SID26752757]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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26
[SID17389928]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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27
[SID56314831]
Potency 1.122qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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28
[SID17389928]
Potency 3.5481qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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29
[SID144208949]
Potency-Replicate_1 15.3553qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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30
[SID56314831]
Potency 22.3872qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624287, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
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31
[SID144211207]
Potency-Replicate_1 61.6448qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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32
[SID144208949]
Potency-Replicate_1 61.6901qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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33
[SID144208949]
ER Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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34
[SID144208949]
Ratio Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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35
[SID144208949]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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36
[SID144208949]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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37
[SID144211207]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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38
[SID144211207]
ER Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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39
[SID144211207]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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40
[SID144211207]
Ratio Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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41
[SID144211207]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
42
[SID144211207]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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43
[SID56314831]
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors of ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ASAP1) [AID624377, Type: screening]arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform 2 [Homo sapiens] [gi:351542238]
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44
[SID56314831]
Mycobacterium tuberculosis BioA enzyme inhibitor Measured in Biochemical System Using Plate Reader - 2163-01_Inhibitor_SinglePoint_HTS_Activity [AID602481, Type: screening]bioA [Mycobacterium tuberculosis UT205] [gi:378544807]
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45
[SID144211207]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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46
[SID144211207]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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47
[SID144211207]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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48
[SID144208949]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743217, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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49
[SID144211207]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743239, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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50
[SID144211207]
qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743240, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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