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10K-362S (CID 1472225) - Compound BioActivity Data
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BioActivity Outcomes:
Active(124)
 
 
Inactive(524)
 
 
Inconclusive(25)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(38)
 
 
 
Bcl-2 like(12)
 
 
 
alkPPc(12)
 
 
KCNQ channel(8)
 
 
 
SWIB(6)
 
 
BioAssay Types:
Screening(477)
 
 
 
 
 
Confirmatory(176)
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(77)
 
 
 
 
IC50(61)
 
 
 
 
EC50(22)
 
 
 
 
AC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 613    Data Row: 674   Total Pages: 34   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14729216]
CC50 1.12e-06Cytotoxicity counterscreen assay for transcriptional activators of heat shock protein 70 (Hsp70) [AID1259, Type: confirmatory]
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2
[SID14729216]
IC50_Mean 0.16Dose Response selectivity of uHTS chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation in a 697B cell line using a luminescence assay [AID489033, Type: confirmatory]
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3
[SID14729216]
IC50 0.2A High Throughput Confirmatory Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in the absence of Glycerol [AID449764, Type: confirmatory]
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4
[SID14729216]
IC50 0.2High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media [AID449762, Type: confirmatory]
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5
[SID14729216]
IC50_Mean 0.32Dose response confirmation of uHTS chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation in a Jurkat cell line using a luminescence assay [AID489035, Type: confirmatory]
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6
[SID14729216]
IC50 0.396Fluorescence dose response cell-based high throughput screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4) [AID1692, Type: confirmatory]Sphingosine-1-phosphate receptor 4 [Homo sapiens] [gi:15929025]
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7
[SID14729216]
IC50 0.752Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA [AID856, Type: confirmatory]sphingosine 1-phosphate receptor 2 [Homo sapiens] [gi:134244587]
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8
[SID14729216]
Mean Mutant EC50 0.84E3 Ligase_Mutant_Dose Response [AID1442, Type: confirmatory]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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9
[SID14729216]
AC50_uM 0.8547Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis [AID449756, Type: confirmatory]
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10
[SID14729216]
IC50 0.87907Luminescence-based dose response cell-based high throughput screening assay for cytotoxic compounds using the IEC-6 intestinal epithelial cell line. [AID1972, Type: confirmatory]
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11
[SID14729216]
EC50 0.96E3 Ligase dose-response_384 [AID1394, Type: confirmatory]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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12
[SID14729216]
IC50 0.967Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor [AID851, Type: confirmatory]sphingosine 1-phosphate receptor 2 [Homo sapiens] [gi:134244587]
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13
[SID14729216]
Potency 1qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction [AID1461, Type: confirmatory]neuropeptide S receptor isoform A [Homo sapiens] [gi:46395496]
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14
[SID14729216]
AC50_uM 1.3ATP-based Luminescence in the Absence of Cytokines Measured in Cell-Based System Using Plate Reader - 2061-06_Inhibitor_Dose_CherryPick [AID463229, Type: confirmatory]
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15
[SID14729216]
Mean Wild-type EC50 1.73E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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16
[SID14729216]
CC50 2.129A Cell Based Secondary Assay To Explore Cytotoxicity of Compounds that Inhibit Mycobacterium Tuberculosis [AID435019, Type: confirmatory]
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17
[SID14729216]
Potency 2.2387Confirmation Concentration-Response Assay for Antagonists of the Neuropeptide S Receptor: Calcium Signal Transduction [AID1489, Type: confirmatory]neuropeptide S receptor isoform A [Homo sapiens] [gi:46395496]
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18
[SID14729216]
Potency 2.2387Confirmation Concentration-Response Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction [AID1491, Type: confirmatory]neuropeptide S receptor isoform A [Homo sapiens] [gi:46395496]
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19
[SID14729216]
IC50 2.255Dose Response screen for antagonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule antagonists hits of the APJ receptor [AID463214, Type: confirmatory]type-1 angiotensin II receptor isoform 1 [Homo sapiens] [gi:4501997]
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20
[SID14729216]
IC50 3.76uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay [AID1778, Type: confirmatory]kappa-type opioid receptor isoform 1 [Homo sapiens] [gi:39725940]
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